Navigation Links
Effectiveness of progesterone in reducing preterm births may be altered by genetic predisposition
Date:1/29/2009

re more or less likely to respond to 17P for the prevention of recurrent spontaneous preterm birth.

All patients had at least one prior spontaneous preterm birth. The study extracted DNA from the saliva of 389 patients, and then genotyped 20 SNPs in the region of the progesterone receptor gene. Two hundred and fifty-eight (66 percent) of the study participants received 17P and 131 (34 percent) were controls and received a placebo.

Spontaneous preterm birth was less common among women who received 17P. However, after controlling for factors known to be associated with recurrent prematurity, including smoking, number of prior preterm deliveries, and pre-pregnancy body mass index, two SNPs were identified among African-American patients to be predictive of response to progesterone treatment. There was also an interaction between progesterone treatment and genotype of 3 additional polymorphisms for non-African-American women delivering very preterm (less than 32 weeks gestation).

Today's award-winning study, The Relationship Between Polymorphisms in the Human Progesterone Receptor and Clinical Response to 17 Alpha-Hydroxyprogesterone Caproate for the Prevention of Recurrent Spontaneous Preterm Birth, is the sixth study by SMFM members to be honored by the March of Dimes for innovative research focused on preventing premature births. The March of Dimes is conducting a multi-year, multi-million dollar campaign aimed at using research and awareness to reduce the growing rate of premature birth.


'/>"/>

Contact: Elizabeth Lynch
elynch@marchofdimes.com
914-997-4286
March of Dimes Foundation
Source:Eurekalert

1

GOOD

Page: 1 2

Related biology news :

1. UC health news: molecular pathway may predict chemotherapy effectiveness
2. Socioeconomic position associated with effectiveness of HIV drugs
3. MIT model could improve some drugs effectiveness
4. Trial seeks genetic fingerprint for predicting drug effectiveness
5. Quantitative PET imaging finds early determination of effectiveness of cancer treatment
6. Poll Shows Strong Doubts About Effectiveness of Federal Employment Verification System
7. New studies on the Mediterranean diet confirm its effectiveness for chronic disease prevention
8. RNA molecules, delivery system improve vaccine responses, effectiveness
9. New Study Reveals the Emotional Impact and Effectiveness of Negative Campaigning
10. Research shows cells inactive state is critical for effectiveness of cancer treatment
11. Corazonas Foods and Brandeis University partner to create cholesterol-reducing snacks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/16/2009)... DigitalPersona, Inc., a leader in ... an agreement with IBM to deploy a ... technology on IBM SurePOS 500 retail systems. ... applications to more easily and quickly identify ... linked to the individuals who perform them. ...
(Date:12/16/2009)... -- BIO-key International, Inc. (OTC Bulletin Board: ... and finger-based biometric identification solutions, announced that ... Special Shareholder Meeting held today approved the ... to Interact911 Mobile Systems Inc. Of the ... and 1.2% were opposed. ,, (Logo: ...
(Date:12/16/2009)... Texas, Dec. 8, 2009 National ... in industrial measurement and control, and DENSO ... automation using robotics technology, today announced their ... technology with DENSO robotic arms. The collaboration ... research and flexible manufacturing applications. In today,s ...
Breaking Biology News(10 mins):DigitalPersona Fingerprint Sensor Technology Ships on IBM SurePOS 500 Retail Systems 2BIO-key(R) Shareholders Overwhelmingly Approve Sale of Law Enforcement Division 2BIO-key(R) Shareholders Overwhelmingly Approve Sale of Law Enforcement Division 3National Instruments and DENSO Robotics Collaborate to Address New Applications in Industrial Robotics 2National Instruments and DENSO Robotics Collaborate to Address New Applications in Industrial Robotics 3National Instruments and DENSO Robotics Collaborate to Address New Applications in Industrial Robotics 4National Instruments and DENSO Robotics Collaborate to Address New Applications in Industrial Robotics 5Healthcare Providers Rank CSC First in ERP Implementations 54329 1Healthcare Providers Rank CSC First in ERP Implementations 54329 2Healthcare Providers Rank CSC First in ERP Implementations 54329 3Preferred Health Technology Announces Support for MGMAs Project SwipeIT 54325 1Preferred Health Technology Announces Support for MGMAs Project SwipeIT 54325 2Dwayne Johnson Novo Nordisk and the Entertainment Industry Foundation Educate Families about Healthy Living and Diabetes 54321 1Dwayne Johnson Novo Nordisk and the Entertainment Industry Foundation Educate Families about Healthy Living and Diabetes 54321 2Dwayne Johnson Novo Nordisk and the Entertainment Industry Foundation Educate Families about Healthy Living and Diabetes 54321 3
... to direct chemical modifications to specific sites on recombinant ... the pharmaceutical industry has been developed by Carolyn ... Energy,s Lawrence Berkeley National Laboratory and the University of ... for diabetes, can be made in bacterial systems like ...
... year, many people seek emergency treatment for unexplained chest ... Gothenburg, Sweden, indicates several common factors among those affected, ... lifestyle. , Chest pain is a common reason for ... patients are diagnosed with unexplained chest pain, which means ...
... small Georgian town of Reepham in Norfolk are taking part ... East Anglia (UEA). , Like two million homes across ... for warmth and hot water, and the aim of the ... is a viable option. , The renewable fuel being used ...
Other Biology News:Tailor-made recombinant proteins in mammals 2Tailor-made recombinant proteins in mammals 3Tailor-made recombinant proteins in mammals 4Unexplained chest pain can be due to stress 2Trailblazing rural community shows green heating oil a viable option 2
(Date:12/16/2009)... Separations Society will hold its 23rd Annual Technical Conference & Exhibition ... Antonio, Texas. To further impact the separation society and reach out ... announce that the 2010 AFS Annual Technical Conference will be co-located ... ... Minneapolis, MN (PRWEB) December 16, 2009 -- The American Filtration ...
(Date:12/15/2009)... three Department of Energy (DOE) bio-energy research centers, has ... valuable intellectual property. , ... ... Surety, LLC , the leading provider of ... Joint BioEnergy Institute (JBEI), one of three Department of ...
(Date:12/15/2009)... Sky One,Medical, Inc. ("China Sky One Medical" or ... integrated pharmaceutical company developing and producing,over-the-counter drugs in ... the Company has 30 medicines that will be ... Medical Insurance, Industrial Injury Insurance,and Maternity Insurance Medicine ... medicines treat a variety of common ailments and ...
(Date:12/15/2009)... Medical, Inc. (OTC Bulletin Board : AEMD) announced ... Comper have joined the Science Advisory ... Schorey and Dr. Comper are leading researchers in ... of Aethlon Medical, was recently formed to leverage ... being advanced as an adjunct therapy for Hepatitis-C ...
Breaking Biology Technology:American Filtration and Separations Society to Hold 23nd Annual Technical Conference 2American Filtration and Separations Society to Hold 23nd Annual Technical Conference 3American Filtration and Separations Society to Hold 23nd Annual Technical Conference 4Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 2Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 3Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 4Joint BioEnergy Institute Selects Surety's AbsoluteProof to Protect the Integrity and Legally Defend the Authenticity of its Scientific Intellectual Property 5China Sky Medical, Inc. Has 30 Medicines that will Be Included in China's National Insurance Directory 2China Sky Medical, Inc. Has 30 Medicines that will Be Included in China's National Insurance Directory 3Aethlon Medical Appoints Jeff Schorey and Wayne Comper to Exosome Sciences Advisory Board 2Aethlon Medical Appoints Jeff Schorey and Wayne Comper to Exosome Sciences Advisory Board 3Aethlon Medical Appoints Jeff Schorey and Wayne Comper to Exosome Sciences Advisory Board 4Aethlon Medical Appoints Jeff Schorey and Wayne Comper to Exosome Sciences Advisory Board 5
... Trials of Carfilzomib in Relapsed/Refractory Multiple Myeloma and Advanced ... 15 Proteolix, Inc. today announced that data from ... solid tumors will be presented at the 2009 Annual ... being held May 29 - June 2, 2009 in ...
... May 15 PRA International, a leading ... annual meeting for the International Society for Pharmacoeconomics and ... Experts from PRA,s Late Phase Services group will be ... capabilities. PRA,s Late Phase Services group supports global ...
... -- China,Biologic Products, Inc. (OTC Bulletin Board: CBPO) ... plasma-based pharmaceutical companies in the,People,s Republic of China ... at the upcoming China Rising Conference hosted by ... 18, 2009 and the 3rd Annual China,Dragon Call ...
Other Biology Technology:Proteolix to Present Carfilzomib Clinical Data During the 2009 ASCO Annual Meeting 2Proteolix to Present Carfilzomib Clinical Data During the 2009 ASCO Annual Meeting 3PRA International Participating in Pharmacoeconomics and Outcomes Research Conference 2China Biologic Products to Present at CCG IR's China Rising Conference and Oppenheimer's China Dragon Call Conference in New York 2China Biologic Products to Present at CCG IR's China Rising Conference and Oppenheimer's China Dragon Call Conference in New York 3China Biologic Products to Present at CCG IR's China Rising Conference and Oppenheimer's China Dragon Call Conference in New York 4
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
... Product Goat polyclonal to Cholesterol Oxidase ... Reactivity / Specificity Cross-reacts with bacteria. ... Background Information Cholesterol oxidases exist as ... and are implicated in bacterial pathogenesis. In ...
Phospho-PERK (Thr980) Antibody...
Goat polyclonal to BACE1 ( Abpromise for all tested applications). entrezGeneID: 23621 SwissProtID: P56817...
Biology Products: