Navigation Links
Effect of 6 mT SMF on phagocytosis depends on macrophage differentiation degree
Date:12/3/2010

tic cells is the cause of several diseases."

The research team studied the effects of 6 mT SMF on the phagocytosis process of differentiating macrophages by using human Kupffer cells, Raw 264,7 macrophages and 12-O-tetradecanoylphorbol-13-acetate [TPA]-differentiated THP-1 monocytes and U937 promonocytes. Indeed, macrophage phagocytosis is the basis of innate immunity and the exposure to Static Magnetic Fields could interfere with a correct immunoresponse. In particular, with this study, the researchers aimed to verify the effect of 6 mT SMF on the phagocytosis mechanism and to compare these effects with those on other internalization processes, like endocytosis.

For many years this research team has focused its interest on the study of the biological effects of SMFs, in particular, moderate intensity (ranging from1 mT to 1 T) SMF that represents the lowest intensity able to interfere with the apoptotic process in relation to apoptotic cell death. Results obtained indicating that [1] SMF significantly influences the phagocytosis of apoptotic cells and latex beads, and to a lesser extent, fluid phase endocytosis and that [2] the effect of SMF is dependent on the degree of macrophage differentiation, validate that the primary site of action of SMF is at the plasma membrane. Indeed, the plasma membrane has a pivotal role in the recognition of apoptotic cells and for their engulfment through connection with the cytoskeleton. 6 mT SMF is able to modify cell surface morphology, distribution of plasma membrane proteins, receptors and sugar residues, and disarrange the cytoskeleton.

Dr Dini said "On the basis of the results obtained in this study in human primary macrophages, even if it is not yet possible to foresee application in medicine, it follows that it is better to avoid exposure of patients bearing a wound, inflammatory foci or abnormal production of apoptotic cells to machinery (including medical equipment) producing moderate intensity
'/>"/>

Contact: Dr. Luciana Dini
Luciana.dini@unisalento.it
Society for Experimental Biology and Medicine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Long-term study shows effect of climate change on animal diversity
2. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
3. Prolonged effects of a warming anomaly on grasslands
4. Cholesterol-lowering drugs and the effect on muscle repair and regeneration
5. Commercial aquatic plants offer cost-effective method for treating wastewater
6. Effects of anthropogenic sound on marine mammals -- a research strategy
7. UC Riverside biochemists devise method for bypassing aluminum toxicity effects in plants
8. How to build crops that can beat aluminums toxic effects
9. RNA molecules, delivery system improve vaccine responses, effectiveness
10. Ripple effect: Water snails offer new propulsion possibilities
11. Cost-effective farm waste-to-energy technology focus of research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/24/2015)... TOWN, South Africa , August 24, 2015 ... Germany ,s largest biometrics manufacturer DERMALOG and ... with the "2015 African Biometrics Company of the Year ... in Nigeria .   -Cross ... and http://www.presseportal.de/nr/8896 - On Thursday evening, ...
(Date:8/20/2015)... , Aug. 20, 2015   Sensory, ... on improving the user experience and security of ... technologies, today announced that its TrulySecure™ ... authentication software to be FIDO Certified™. ... for compliance with the FIDO UAF (Universal Authentication ...
(Date:8/18/2015)... 2015  Navitas today announced that it ... Submission Content Management webinar scheduled on August ... to the Implementation of Regulatory Submission Standards ... industry, vendors, health authorities, consultants and the ... a standard method of implementing electronic submission ...
Breaking Biology News(10 mins):Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 2Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3
... CAMBRIDGE, Mass. -- Clinical trials using patients, own immune cells ... usually works only if the patients also receive large doses ... those drugs have life-threatening side effects. Now a team ... necessary drugs by smuggling them on the backs of the ...
... Researchers at North Carolina State University have developed ... with biological systems including the human body. Their ... environmental safety in the handling of nanomaterials, as well ... Dr. Jim Riviere, Burroughs Wellcome Distinguished Professor of ...
... July 26 Aware, Inc. (Nasdaq: www.aware.com/ir . ... 719-457-2621 and referencing the confirmation number 5684541.  A replay ... after the call. About Aware ... for the telecommunications and biometrics industries. Aware has pioneered ...
Cached Biology News:Drugs encased in nanoparticles travel to tumors on the surface of immune-system cells 2Drugs encased in nanoparticles travel to tumors on the surface of immune-system cells 3Probing the nanoparticle: Predicting how nanoparticles will react in the human body 2Aware, Inc. Reports Second Quarter 2010 Financial Results 2Aware, Inc. Reports Second Quarter 2010 Financial Results 3Aware, Inc. Reports Second Quarter 2010 Financial Results 4Aware, Inc. Reports Second Quarter 2010 Financial Results 5Aware, Inc. Reports Second Quarter 2010 Financial Results 6Aware, Inc. Reports Second Quarter 2010 Financial Results 7Aware, Inc. Reports Second Quarter 2010 Financial Results 8Aware, Inc. Reports Second Quarter 2010 Financial Results 9Aware, Inc. Reports Second Quarter 2010 Financial Results 10Aware, Inc. Reports Second Quarter 2010 Financial Results 11Aware, Inc. Reports Second Quarter 2010 Financial Results 12Aware, Inc. Reports Second Quarter 2010 Financial Results 13Aware, Inc. Reports Second Quarter 2010 Financial Results 14Aware, Inc. Reports Second Quarter 2010 Financial Results 15Aware, Inc. Reports Second Quarter 2010 Financial Results 16Aware, Inc. Reports Second Quarter 2010 Financial Results 17Aware, Inc. Reports Second Quarter 2010 Financial Results 18Aware, Inc. Reports Second Quarter 2010 Financial Results 19Aware, Inc. Reports Second Quarter 2010 Financial Results 20Aware, Inc. Reports Second Quarter 2010 Financial Results 21Aware, Inc. Reports Second Quarter 2010 Financial Results 22
(Date:8/27/2015)... , Aug. 27, 2015  Asterias Biotherapeutics, Inc. (NYSE ... field of regenerative medicine, today announced that executives from ... the month of September.  , ... Rodman & Renshaw,s 17th Annual Global Investment Conference on ... the St. Regis Hotel in New York ...
(Date:8/27/2015)... -- HUYA Bioscience International (HUYA) today announced the sponsorship of ... HTLV-1, held this week at the University of Tokyo ... is to promote research on HTLV-1 and HTLV-1-associated diseases, ... research related to these fields to advance science, the ... to support this prestigious conference," said Mireille Gillings ...
(Date:8/27/2015)... ... August 27, 2015 , ... Inc. Magazine released its annual ... Solutions as number 1,361 in growth for the three years through 2014. Being named ... fastest-growing privately held organizations in the country. , “We are thrilled to make ...
(Date:8/27/2015)... Aug. 27, 2015 In response to ... UPS and The US Postal Service to no ... as ,select agents, by the CDC, Marken reaffirmed ... these sensitive shipments. Marken uses its ... trained and certified personnel to ensure the safe ...
Breaking Biology Technology:Asterias Biotherapeutics to Present at Upcoming Investor Conferences 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 4iLab Solutions Named to 2015 Inc. 5000 List 2iLab Solutions Named to 2015 Inc. 5000 List 3Marken Ensures Safe Transportation Of Select Agents And Toxins 2
... PharmSource Lead Sheet upgrades database resources to help companies serving ... , ... Springfield, VA (PRWEB) November ... Information Services, Inc. (PharmSource) announces the expansion of its PharmSource ...
... quantum computing is that it will dramatically outshine traditional ... factoring large numbers, creating uncrackable codes and simulating the ... that direction, if you,ll pardon the pun, has been ... a paper published in the journal Nature . ...
... ARBOR, Mich., Nov. 21 MichBio, the association ... service providers to its fourth annual Expo on ... Financial ShowPlace in Novi, MI. The MichBio ... industry professionals.,In addition, this year,s event attracted 56 ...
Cached Biology Technology:PharmSource Introduces Proprietary Resource for Identifying New Business Opportunities in Bio/Pharma 2Stanford: Quantum computing spins closer 2MichBio Expo Draws Nearly 500 Professionals; Career Day Raises Profile 2MichBio Expo Draws Nearly 500 Professionals; Career Day Raises Profile 3
... Cell Transformation Detection Assay is an anchorage-independent ... considered the most stringent assay for detecting ... assay, cells (pre-treated with carcinogens or carcinogen ... soft agar medium for 21-28 days. ...
The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver une...
... EZ DNA Methylation Kit uses a simplified ... DNA methylation analysis. The kit is based ... place between cytosine and sodium bisulfite where ... DNA Methylation Kits innovative in-column desulphonation reaction ...
... Gels easier and more efficient by providing ... types of pre-cut pre-assembled membrane/filter paper sandwiches ... cm E-PAGE Gels*. The available nitrocellulose and ... transfer of proteins (Figure 1 Table 1). ...
Biology Products: