Navigation Links
Eating fish may explain very low levels of heart disease in Japan
Date:7/28/2008

PITTSBURGH, July 28 Consuming large quantities of fish loaded with omega-3 fatty acids may explain low levels of heart disease in Japan, according to a study led by the University of Pittsburgh Graduate School of Public Health slated for the Aug. 5 issue of the Journal of the American College of Cardiology and available online at 5 p.m. ET, today. The study also found that third- and fourth-generation Japanese Americans had similar or even higher levels of atherosclerosis, or hardening of the arteries a major risk factor for heart disease, compared to white Americans.

The very low rate of heart disease in Japan among developed countries has been puzzling. Death rates from coronary heart disease in Japan have been less than half of that in the U.S. This holds true even among Japanese men born after World War II who adopted a Western lifestyle since childhood, and despite the fact that among these same men, risk factors for coronary heart disease (serum levels of total cholesterol, blood pressure and rates of type 2 diabetes) are very similar among men in the U.S. Additionally, the rate of cigarette smoking, another major risk factor, has been infamously high in Japan.

The study was conducted at two universities and one research institute in the U.S. and Japan to compare serum levels of omega-3 fatty acids and atherosclerosis among Japanese, white American and Japanese American men. Based on data from 868 men between the ages of 40 and 49, Japanese men had the lowest levels of atherosclerosis and two times higher levels of omega-3 fatty acids than white Americans or Japanese Americans.

The differences in the levels of atherosclerosis between Japanese and white Americans remained after adjusting for other risk factors serum cholesterol, blood pressure, cigarette smoking, body mass index and diabetes.

"Our study suggests that very high levels of omega-3 fatty acids have strong properties that may help prevent the buildup of cholesterol in the arteries," said Akira Sekikawa, M.D., Ph.D., study lead author and assistant professor of epidemiology at the University of Pittsburgh Graduate School of Public Health. "Increasing fish intake to two times a week for healthy people is currently recommended in the U.S. Our study shows much higher intake of fish observed in the Japanese may have strong anti-atherogenic effect."

Fish consumption among the Japanese is one of the highest in the world. Japanese men consume an average of 100 grams, equivalent to about 3.75 ounces, of fish every day from early in life. Meanwhile, Americans typically eat fish less than two times a week.

"The Japanese eat a very high level of fish compared to other developed countries," said Dr. Sekikawa. "While we don't recommend Americans change their diets to eat fish at these quantities because of concerns about mercury levels in some fish, increasing intake of omega-3 fatty acids in the U.S. could have a very substantial impact on heart disease. Given the similar levels of atherosclerosis in Japanese Americans and white Americans, it also tells us that lower levels of heart disease among Japanese men are much more likely lifestyle related than a result of genetic differences," said Dr. Sekikawa.

Omega-3 fatty acids are a type of polyunsaturated fat found primarily in fish. The two most potent omega-3 fatty acids are known as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and are usually found in oily fishes, such as mackerel, salmon and tuna.


'/>"/>

Contact: Clare Collins
CollCX@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Related biology news :

1. Why eating less can help the environment
2. New guidelines for treating rheumatoid arthritis
3. Tumor-inhibiting protein could be effective in treating leukemia
4. Hebrew University develops novel approach for treating mitochondrial disorders
5. Cellular self-eating promotes pancreatitis
6. Treating chronic pain, migraine & muscle spasticity through inhibition of neurotransmitter glutamate
7. Body image program reduces onset of obesity and eating disorders
8. Why fruit-eating bats eat dirt
9. Argonne scientists develop techniques for creating molecular movies
10. Evidence now suggests eating soy foods in puberty protects against breast cancer
11. Where college students live can impact their weight, eating and exercise habits
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/21/2016)... March 22, 2016 Unique ... passcodes for superior security   ... provider of secure digital communications services, today announced it ... and offer enterprise customers, particularly those in the Financial ... and voice authentication within a mobile app, alongside, and ...
(Date:3/14/2016)... 2016 NXTD ) ("NXT-ID" or the ... announces the airing of a new series of commercials on ... March 21 st .  The commercials will air on Bloomberg ... on the Street show. --> NXTD ) ("NXT-ID" ... commerce market, announces the airing of a new series of ...
(Date:3/10/2016)...   Unisys Corporation (NYSE: UIS ) today ... is testing its biometric identity solution at the Otay Mesa ... help identify certain non-U.S. citizens leaving the country. ... help determine the efficiency and accuracy of using biometric technologies ... run until May 2016. --> the United ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... ... April 28, 2016 , ... As part of an ... experts, and expanding its LATAM network and logistics capabilities. Enhancements have been ... their clinical trial projects. , The expansion will provide unmatched clinical trial logistics ...
(Date:4/27/2016)... ... April 27, 2016 , ... ... mobile devices with fingerprint recognition for secure access, voice recognition for hands-free communication, ... ways consumers are interacting with biometrics technology today. But if they asked ...
(Date:4/27/2016)... ... April 27, 2016 , ... PathSensors, Inc., a leading ... Dr. Lamka will assist PathSensors in expanding the use of the company‚Äôs CANARY® ... CANARY® test platform for the detection of harmful pathogens, including a number of ...
(Date:4/27/2016)... April 27, 2016 ReportsnReports.com ... with specific focus on US, EU, ... , to the healthcare business intelligence collection of ... Complete report on the Flow Cytometry market ... supported with 282 tables and figures is now ...
Breaking Biology Technology: