Navigation Links
Eating fish may explain very low levels of heart disease in Japan
Date:7/28/2008

PITTSBURGH, July 28 Consuming large quantities of fish loaded with omega-3 fatty acids may explain low levels of heart disease in Japan, according to a study led by the University of Pittsburgh Graduate School of Public Health slated for the Aug. 5 issue of the Journal of the American College of Cardiology and available online at 5 p.m. ET, today. The study also found that third- and fourth-generation Japanese Americans had similar or even higher levels of atherosclerosis, or hardening of the arteries a major risk factor for heart disease, compared to white Americans.

The very low rate of heart disease in Japan among developed countries has been puzzling. Death rates from coronary heart disease in Japan have been less than half of that in the U.S. This holds true even among Japanese men born after World War II who adopted a Western lifestyle since childhood, and despite the fact that among these same men, risk factors for coronary heart disease (serum levels of total cholesterol, blood pressure and rates of type 2 diabetes) are very similar among men in the U.S. Additionally, the rate of cigarette smoking, another major risk factor, has been infamously high in Japan.

The study was conducted at two universities and one research institute in the U.S. and Japan to compare serum levels of omega-3 fatty acids and atherosclerosis among Japanese, white American and Japanese American men. Based on data from 868 men between the ages of 40 and 49, Japanese men had the lowest levels of atherosclerosis and two times higher levels of omega-3 fatty acids than white Americans or Japanese Americans.

The differences in the levels of atherosclerosis between Japanese and white Americans remained after adjusting for other risk factors serum cholesterol, blood pressure, cigarette smoking, body mass index and diabetes.

"Our study suggests that very high levels of omega-3 fatty acids have strong properties that may help prevent the buildup of cholesterol in the arteries," said Akira Sekikawa, M.D., Ph.D., study lead author and assistant professor of epidemiology at the University of Pittsburgh Graduate School of Public Health. "Increasing fish intake to two times a week for healthy people is currently recommended in the U.S. Our study shows much higher intake of fish observed in the Japanese may have strong anti-atherogenic effect."

Fish consumption among the Japanese is one of the highest in the world. Japanese men consume an average of 100 grams, equivalent to about 3.75 ounces, of fish every day from early in life. Meanwhile, Americans typically eat fish less than two times a week.

"The Japanese eat a very high level of fish compared to other developed countries," said Dr. Sekikawa. "While we don't recommend Americans change their diets to eat fish at these quantities because of concerns about mercury levels in some fish, increasing intake of omega-3 fatty acids in the U.S. could have a very substantial impact on heart disease. Given the similar levels of atherosclerosis in Japanese Americans and white Americans, it also tells us that lower levels of heart disease among Japanese men are much more likely lifestyle related than a result of genetic differences," said Dr. Sekikawa.

Omega-3 fatty acids are a type of polyunsaturated fat found primarily in fish. The two most potent omega-3 fatty acids are known as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and are usually found in oily fishes, such as mackerel, salmon and tuna.


'/>"/>

Contact: Clare Collins
CollCX@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Related biology news :

1. Why eating less can help the environment
2. New guidelines for treating rheumatoid arthritis
3. Tumor-inhibiting protein could be effective in treating leukemia
4. Hebrew University develops novel approach for treating mitochondrial disorders
5. Cellular self-eating promotes pancreatitis
6. Treating chronic pain, migraine & muscle spasticity through inhibition of neurotransmitter glutamate
7. Body image program reduces onset of obesity and eating disorders
8. Why fruit-eating bats eat dirt
9. Argonne scientists develop techniques for creating molecular movies
10. Evidence now suggests eating soy foods in puberty protects against breast cancer
11. Where college students live can impact their weight, eating and exercise habits
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... 15, 2016  A new partnership announced today ... underwriting decisions in a fraction of the time ... and high-value life insurance policies to consumers without ... With Force Diagnostics, rapid testing (A1C, Cotinine and ... (blood pressure, weight, pulse, BMI, and activity data) ...
(Date:4/13/2016)... , April 13, 2016  IMPOWER physicians supporting Medicaid ... setting a new clinical standard in telehealth thanks to ... leveraging the higi platform, IMPOWER patients can routinely track ... and body mass index, and, when they opt in, ... convenient visit to a local retail location at no ...
(Date:3/29/2016)... LegacyXChange, Inc. (OTC: LEGX ... Protect are pleased to announce our successful effort to ... of writing instruments, ensuring athletes signatures against counterfeiting and ... athletes on LegacyXChange will be assured of ongoing proof ... Bill Bollander , CEO states, "By inserting ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... Despite the volatility that continues to envelop the ... research on ActiveWallSt.com directs the investor community,s focus on the ... ), Cerus Corp. (NASDAQ: CERS ), Arrowhead Pharmaceuticals ... Inc. (NASDAQ: FPRX ). Register with us today ... On Wednesday, shares in Massachusetts ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... FireflySci cuvettes are used in leading laboratories all over the globe. Their ... , In addition to manufacturing awesome cuvettes, FireflySci makes spectrophotometer calibration standards that ...
(Date:5/25/2016)... ... May 25, 2016 , ... The ... fracture-specific plating options designed to address fractures of the distal tibia and fibula. ... The Acumed Ankle Plating System 3 is composed of seven plate families that ...
(Date:5/25/2016)... ... ... at the University of Athens say they have evidence that the variety of different ... lead to one good one. Surviving Mesothelioma has just posted an article on the ... 98 mesothelioma patients who got a second kind of drug therapy after ...
Breaking Biology Technology: