Navigation Links
Eating broccoli could guard against arthritis
Date:9/15/2010

Scientists at the University of East Anglia (UEA) are launching a groundbreaking new project to investigate the benefits of broccoli in the fight against osteoarthritis.

Initial laboratory research at UEA has found that a compound in broccoli called sulforaphane blocks the enzymes that cause joint destruction in osteoarthritis the most common form of arthritis.

Broccoli has previously been associated with reduced cancer risk but this is the first major study into its effects on joint health.

With funding from both Arthritis Research UK and the Diet and Health Research Industry Club (DRINC), the 650,000 project will explore how sulforaphane may act to slow or prevent the development of osteoarthritis. It will prepare the way for the first patient trials and could lead to safe new ways of preventing and treating this painful disease.

Sulforaphane is a bioactive compound found in cruciferous vegetables, particularly broccoli. Eating broccoli leads to a high level of sulforaphane in the blood, but scientists don't yet know if the sulforaphane gets into joints in sufficient amounts to be effective. This is one of the things that the UEA team hopes to discover.

Osteoarthritis is the leading cause of disability in the UK where it affects around six million people. It is a degenerative joint disease which gradually destroys the cartilage in the joints, particularly in the hands, feet, spine, hips and knees of older people. There is currently no effective treatment other than pain relief or joint replacement.

Prof Ian Clark, of UEA's School of Biological Sciences, who is leading the research said: "The UK has an aging population and developing new strategies for combating age-related diseases such as osteoarthritis is vital to improve the quality of life for sufferers but also to reduce the economic burden on society."

As part of the three-year project, the UEA team will also investigate the effects of other dietary compounds on osteoarthritis, including diallyl disulphide which is found in high amounts in garlic and also appears to slow the destruction of cartilage in laboratory models.


'/>"/>

Contact: Cat Bartman
c.bartman@uea.ac.uk
44-016-035-93007
University of East Anglia
Source:Eurekalert

Related biology news :

1. Antibacterial peptide could aid in treating soldiers burn wound infections
2. Scientists discover oldest evidence of human stone tool use and meat-eating
3. Oil-eating bacteria may determine environmental impact of Gulf oil
4. New research: Sugar substitutes help reduce caloric intake without overeating or hunger
5. Treating tongue tie could help more babies breastfeed
6. Birds reduce their heating bills in cold climates
7. Genetically modified cell procedure may prove useful in treating kidney failure
8. Delineating primary and secondary organic carbon in neoproterozoic glacial sediments
9. Grinding mouth, wrinkle eye: Penn graduate student describes new species of plant-eating dinosaur
10. Scripps Research scientists break barrier to creating potential therapeutic molecules
11. A new effective strategy for treating tobacco addiction was developed by researchers from the CAS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... LONDON , April 26, 2016 ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... a partnership to integrate the Onegini mobile security ... (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ) The ... enhanced security to access and transact across channels. ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:4/15/2016)... , April 15, 2016 ... the,  "Global Gait Biometrics Market 2016-2020,"  report to ... http://photos.prnewswire.com/prnh/20160330/349511LOGO ) , ,The global gait biometrics ... of 13.98% during the period 2016-2020. ... angles, which can be used to compute factors ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... discussions on a range of subjects including policies, debt and ... Poloz. Speaking at a lecture to the Canadian ... to the country,s inflation target, which is set by both ... "In certain areas there needs to be ... why not sit down and address strategy together?" ...
(Date:6/24/2016)... ... ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension of 8.5 ... end machines that use the more unconventional z-dimension of 20mm. Z-dimension or ... the cuvette holder. , FireflySci has developed several Agilent flow cell product lines ...
(Date:6/23/2016)... ... June 23, 2016 , ... Mosio, ... second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced clinical ... eBook by providing practical tips, tools, and strategies for clinical researchers. , “The ...
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
Breaking Biology Technology: