Navigation Links
Early light refines the brain's circuitry for vision
Date:6/5/2011

assess the effect of light on retinal waves, Renna used electrodes to record the activity of cells in the inner retinas of newborn mice, first recording in the dark, then in the light, and then again in the dark. In every case retinas experienced waves, but when the retinas were exposed to light, the waves lasted about 50 percent longer.

Renna then tested whether the light-sensitive cells were really creating this wave-lengthening effect by repeating the study in "knock-out" mice in which the ability of the ipRGCs to sense light had been genetically abolished. With the cells disabled, exposure to light no longer made any difference in the duration of the waves.

Finally, to assess the effect of light on the left-right sorting process in the dLGN, Renna examined the tissues from normal mice and the mice whose ipRGCs couldn't sense light. In each case he fluorescently labeled the nerve endings from one eye red and the other green. A computer comparison of the tissues showed that the normal mice developed a higher degree of segregation between red and green than the knockout mice. In other words, the ability of ipRGCs to sense light improved sorting out one eye from another in the dLGN.

Twinkling tadpoles

In his study, Aizenman collaborated with Arto Nurmikko, professor of engineering and physics, to investigate the function of in the optic tectum of tadpole brains. They flooded the tectal neurons in live tadpoles with a molecule that makes calcium ions fluoresce. As whole networks of neurons became active, they'd take in the ions and glow. The researchers recorded the tadpoles with a high-resolution, high-speed camera that could capture the millisecond-to-millisecond activity of the neurons.

Led in the lab by engineering graduate student Heng Xu, the lead author, and postdoctoral researcher Arseny Khakhalin, the team reared some young tadpoles under normal conditions of 12 hours of light and 12 hours of darkness durin
'/>"/>

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Harvard scientists see the early cellular cause of dry eye disease for the first time
2. Women who start prenatal vitamins early are less likely to have children with autism
3. Targeted adalimumab treatment can optimize long-term outcomes for patients with early RA
4. JGIs Susannah Tringe receives prestigious $2.5M DOE Early Career Research Award
5. A tale of 2 lakes: One gives early warning signal for ecosystem collapse
6. Early cancer treatment successes lead to CAREER Award for Rafael Davalos
7. Protein adaptation shows that life on early earth lived in a hot, acidic environment
8. Public forum: Japan and early lessons for the nuclear industry
9. Pancreatic Cancer Action Network-AACR Pathway to Leadership Grants awarded to early-career investigators
10. Nearly 1 in 4 postmenopausal women with fractures is obese
11. New technology to improve early detection and prognosis of cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... 31 de julio de 2015 La 10 th ... celebrará por medio de BGI del 22 al 25 de octubre ... Este año, la conferencia celebra su décimo aniversario. ... convertido en una de las reuniones anuales más influyentes del ... las reuniones más dinámicas, entusiastas y mejores a nivel científico. ...
(Date:7/27/2015)... 27, 2015  Synaptics Inc. (NASDAQ: SYNA ... today announced that Huawei has selected the Synaptics ... its stylish smartwatch. Huawei chose the state-of-the-art ClearPad ... power and highly responsive human interface qualities such ... also required a classic round watch face and ...
(Date:7/21/2015)... , July 21, 2015  NXT-ID, Inc. ... a biometric authentication company focused on the growing ... smart wallet, announces that it has filed provisional ... and Method. This invention highlights ... only authorizes an account, but also the user ...
Breaking Biology News(10 mins):La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 2NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 4
... OAK RIDGE, Tenn., Jan. 17, 2008 -- Oak ... work for the automotive supplier industry initiated through ... Technologies, or USAutoPARTs collaborative announced today at the ... Made up of a consortium of federal and ...
... Troy, N.Y. - Two theoretical physicists at Rensselaer ... the long-sought-after pathway that an HIV peptide takes ... years of biocomputation and simulation to uncover a ... penetrates the cell membrane. The discovery could help ...
... federal fishery agencies, regional management councils, universities, conservation groups, ... the Cocoanut Grove conference center in Santa Cruz, Calif., ... Groundfish Conference. The Western Groundfish Conference is ... Mary Yoklavich, research biologist with NOAA Fisheries Service. It ...
Cached Biology News:Oak Ridge to lead auto supplier R&D partnership 2Oak Ridge to lead auto supplier R&D partnership 3Researchers reveal HIV peptide's possible pathway into the cell 2Researchers reveal HIV peptide's possible pathway into the cell 3
(Date:7/30/2015)... over 60,000 customers across the globe, ISN improves the efficiency and effectiveness of contractor ... 60,000 safe and reliable contractors in over 80 countries. ... ... Over 60,000 Worldwide Customers In More Than ... Headquartered in Dallas, TX , ISN has additional offices in ...
(Date:7/30/2015)... ... July 30, 2015 , ... ... applications and designed for continuous operation up to 1500 bar. The sanitary design ... efficiency, and preventing toxic contamination. , The Pony™ NS2006L homogenizer is an ideal ...
(Date:7/29/2015)... Japan (Q2 2015: +14% CER / 20% of sales) ... in China , as well as solid contributions from Korea, ... Europe / Middle East / ... in Germany , Turkey and the ... 49% of sales) grew 11%, excluding U.S. HPV sales, on demand across all ...
(Date:7/29/2015)... 29, 2015 Research ... addition of the "Global Biosimilars Market, 2015 ... The Global Biosimilars Market, 2015 - 2025, ... growing biosimilars market. With the blockbuster biologics losing ... costs, biosimilars are being viewed as viable substitutes ...
Breaking Biology Technology:ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2QIAGEN Reports Results for Second Quarter and First Half of 2015 2QIAGEN Reports Results for Second Quarter and First Half of 2015 3QIAGEN Reports Results for Second Quarter and First Half of 2015 4QIAGEN Reports Results for Second Quarter and First Half of 2015 5QIAGEN Reports Results for Second Quarter and First Half of 2015 6QIAGEN Reports Results for Second Quarter and First Half of 2015 7QIAGEN Reports Results for Second Quarter and First Half of 2015 8QIAGEN Reports Results for Second Quarter and First Half of 2015 9QIAGEN Reports Results for Second Quarter and First Half of 2015 10Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 3
... ... Protection Agency will allow farmers the ability to improve upon the environmental benefits from biotechnology ... weed control platform in corn, to 5 percent in the northern Corn Belt and 20 ... ...
... , NEWARK, N.J., July 21 ... specialty chemical technology based Life Science Company announced today ... testing, BioNeutral,s Ygiene(TM) Hospital Grade Antimicrobial passed the difficult ... 5.4 million spores of Clostridium difficile (C.diff) ...
... Calif., July 21, Varian, Inc. (NasdaqGS: VARI) plans to release its financial ... p.m. Pacific Time (PT) on Wednesday, July 29, 2009. A live webcast ... results is scheduled to follow at 2:00 p.m. PT that same day. ... accessed from Varian, Inc.,s Web site at www.varianinc.com . ...
Cached Biology Technology:EPA Refuge Determination Positive for the Environment 2BioNeutral's Ygiene(TM) Hospital Grade Achieves a 100% Total Kill (Pass) Against the Life Threatening Clostridium Difficile (C.diff) Spores in Independent EPA Required Protocol Testing. 2BioNeutral's Ygiene(TM) Hospital Grade Achieves a 100% Total Kill (Pass) Against the Life Threatening Clostridium Difficile (C.diff) Spores in Independent EPA Required Protocol Testing. 3
Improve inventory management with stainless steel red cell canisters; ensure product safety with CO2 or LN2 backup systems. A complete solution for your blood banking needs....
The mini vertical flow workbench is designed to perform PCR protocols in a particle-free environment. The built-in UV light ensures the elimination of any nucleic acid to avoid cross-contamination....
Request Info...
... Electroporator is a simple, easy to ... in bacterial and yeast applications. ... two voltages and either one mm, ... On pressing the pulse button the ...
Biology Products: