Navigation Links
Early-life exposure of frogs to herbicide increases mortality from fungal disease
Date:10/23/2013

The combination of the herbicide atrazine and a fungal disease is particularly deadly to frogs, shows new research from a University of South Florida laboratory, which has been investigating the global demise of amphibian populations.

USF Biologist Jason Rohr said the new findings show that early-life exposure to atrazine increases frog mortality but only when the frogs were challenged with a chytrid fungus, a pathogen implicated in worldwide amphibian declines. The research is published in the new edition of Proceedings of the Royal Society B.

"Understanding how stressors cause enduring health effects is important because these stressors might then be avoided or mitigated during formative developmental stages to prevent lasting increases in disease susceptibility," Rohr said.

The study was conducted by Rohr and Lynn Martin, Associate Professors of USF's Department of Integrative Biology; USF researchers Taegan McMahon and Neal Halstead; and colleagues at the University of Florida, Oakland University, and Archbold Biological Station.

Their experiments showed that a six-day exposure to environmentally relevant concentrations of atrazine, one of the most common herbicides in the world, increased frog mortality 46 days after the atrazine exposure, but only when frogs were challenged with the chytrid fungus. This increase in mortality was driven by a reduction in the frogs' tolerance of the infection.

Moreover, the researchers found no evidence of recovery from the atrazine exposure and the atrazine-induced increase in disease susceptibility was independent of when the atrazine exposure occurred during tadpole development.

"These findings are important because they suggest that amphibians might need to be exposed only to atrazine briefly as larvae for atrazine to cause persistent increases in their risk of chytri-induced mortality," Rohr said. "Our findings suggest that reducing early-life exposure of amphibians to atrazine could reduce lasting increases in the risk of mortality from a disease associated with worldwide amphibian declines."

Until this study, scientists knew little about how early-life exposure to stressors affected the risk of infectious diseases for amphibians later in life.

"Identifying which, when, and how stressors cause enduring effects on disease risk could facilitate disease prevention in wildlife and humans, an approach that is often more cost-effective and efficient than reactive medicine," Rohr said.

The findings are also the latest chapter in research Rohr and his lab has conducted on the impact of atrazine on amphibians. These findings are consistent with earlier studies that concluded that, while the chemical typically does not directly kill amphibians and fish, there is consistent scientific evidence that it negatively impacts their biology by affecting their growth and immune and endocrine systems.


'/>"/>

Contact: Vickie Chachere
vchachere@usf.edu
813-974-6251
University of South Florida (USF Health)
Source:Eurekalert

Related biology news :

1. NIH awards UCI $10 million to study early-life origins of adolescent mental disorders
2. Flame retardant ban reduces exposures in pregnant women
3. Study reveals link between oil spill exposure and hematologic and hepatic toxicity
4. 1 pill can kill: Effects of unintentional opioid exposure in young children
5. Answering crucial questions about anthrax exposure
6. Early exposure to insecticides gives amphibians higher tolerance later
7. Research reveals low exposure of excellent work by female scientists
8. Exposure to high pollution levels during pregnancy may increase risk of having child with autism
9. Dads life stress exposure can affect offspring brain development, Penn Study finds
10. Fetal neuromaturation associated with mothers exposure to ddt and other environmental contaminants
11. Posttraumatic stress disorder treatment: Genetic predictor of response to exposure therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/19/2016)... , Nov. 18, 2016 Securus Technologies, ... solutions for public safety, investigation, corrections and monitoring, announced ... smaller competitor, ICSolutions, to have an independent technology judge ... the most modern high tech/sophisticated telephone calling platform, and ... customers that they do most of what we do ...
(Date:11/15/2016)...  Synthetic Biologics, Inc. (NYSE MKT: SYN), a ... gut microbiome, today announced the pricing of an ... common stock and warrants to purchase 50,000,000 shares ... the public of $1.00 per share and accompanying ... offering, excluding the proceeds, if any from the ...
(Date:6/27/2016)... Research and Markets has announced the addition of the ... The report forecasts the biometrics ... a CAGR of 12.28% during the period 2016-2020. ... with inputs from industry experts. The report covers the market landscape ... includes a discussion of the key vendors operating in this market. ...
Breaking Biology News(10 mins):
(Date:11/30/2016)... ... November 30, 2016 , ... BEI Kimco, a brand of ... flexure design that ensures high alignment accuracy by preventing unwanted shaft rotation. The ... where extreme precision is required, such as in medical equipment, laboratory instrumentation, clean ...
(Date:11/30/2016)... , Nov. 30, 2016  The Allen ... Cell Collection: the first publicly available collection of ... cells that target key cellular structures with unprecedented ... Research, these powerful tools are a crucial first ... to better understand what makes human cells healthy ...
(Date:11/30/2016)... 2016 Part of 5m$ Investment in ... ... Aptuit, LLC today announced that it had successfully completed the ... compounds have increased the Screening Collection to over 400,000. The ... capabilities of the company. This expansion, complemented by new robotics ...
(Date:11/30/2016)... Research Triangle Park, North Carolina (PRWEB) , ... November 30, 2016 ... ... Chemistry (IUPAC) approved the names and symbols for four elements: nihonium (Nh), moscovium ... , Following a 5-month period of public review, the names earlier proposed by the ...
Breaking Biology Technology: