Navigation Links
Early isolation linked to enhanced response to cocaine
Date:4/16/2009

NEW ORLEANSDrug addiction affects millions of people around the world, causing numerous problems ranging from emotional and psychological difficulties to physical and health issues. Initial drug use can be motivated by curiosity or peer pressure, but in some animals, such as rats, it can also be the result of a stressful early life event, such as social isolation. A new study examines the impact of social isolation on the animal's response to cocaine.

The study, Social Isolation During Perinatal Development Alters the Behavioral Response to Cocaine in Juvenile Rats, was conducted by Natasha Lugo-Escobar, Nicole Carreras and Annabell C. Segarra, University of Puerto Rico, School of Medicine, Rio Piedras, PR. The team will present its findings at the 122nd Annual Meeting of the American Physiological Society (APS; www.the-aps.org/press), which is part of the Experimental Biology 2009 scientific conference. The meeting will be held April 18-22, 2009 in New Orleans.

The Study

Drugs of abuse act on the reward centers of the brain. These areas are normally involved in mediating pleasure, and also regulate the psycho-stimulant effects of drugs such as cocaine. Stress is known to enhance drug seeking behavior, as well as the psychostimulant effects of cocaine. Since rats are social animals, isolation was used as a stressor to explore the association between stress during development and susceptibility to the psychostimulant effects of drugs of abuse, such as cocaine.

Rats were stressed: (1) as fetuses (by housing the pregnant mother alone), (2) as neonates (by isolating newborn rats for 1 hr daily during the first 9 days of life) or as adolescents (by housing each rat separately during days 21-35). Two additional groups: (4) isolated as fetuses, neonates and adolescents and (5) controls - not isolated during any developmental period, comprised the 5 groups studied. When rats reac
'/>"/>

Contact: Donna Krupa
dkrupa@the-aps.org
703-967-2751
American Physiological Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. Early administration of antiretroviral therapy can improve survival
2. Compendium of pancreatic cancer biomarkers established as strategic approach to early-detection
3. Novel lung cancer vaccine shows promise in fighting early-stage lung cancer
4. Early family ties: No sponge in the human family tree
5. Two innovative University of Texas at Austin biologists become HHMI Early Career Scientists
6. Two Hutchinson Center researchers named HHMI Early Career Scientists
7. Peter Baumann named Howard Hughes Medical Institute Early Career Scientist
8. Whitehead member Peter Reddien named HHMI Early Career Scientist
9. Deep-sea rocks point to early oxygen on Earth
10. No consistent advantage for planting soybean early
11. Study to evaluate success of parental involvement in early childhood education
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... nature as something that we enjoy when we visit a ... we think of ourselves as a part of nature? A ... a house? , The answers to these questions reflect ... our speech and in cultural artifacts. , A new Northwestern ... American Indian Center of Chicago and the Menominee tribe of ...
(Date:9/30/2014)... professor and Howard Hughes Medical Institute investigator, and ... recipients in the 2014 round of grants from ... BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative ... September 30, provides more than $3 million in ... , The BRAIN Initiative, launched last year, is ...
(Date:9/30/2014)... German . ... foods in the world. Because they grow underground, people use ... smell of truffles is not only of interest to gourmets. ... of the Goethe University Frankfurt have discovered that the smell ... are trapped inside truffle fruiting bodies. , White truffles from ...
Breaking Biology News(10 mins):The cultural side of science communication 2Salk scientists receive $3 million for BRAIN Initiative grant 2On the trail of the truffle flavor 2
... discovered in the open ocean may force scientists to rethink ... ecosystems. A paper describing the new findings appears in ... A research team led by Jonathan Zehr, a marine ... new microbe by analyzing its genetic material, even though researchers ...
... unveils new equipment to make cancer treatment safer ... National Physical Laboratory (NPL) today will help improve the ... electron linear accelerator (linac) will help ensure patients are ... treats cancer, by using ionising radiation such as high-energy ...
... lives in remarkable ways by providing food and water, ... they are experiencing loss and degradation on a massive ... water for long enough periods to support plants that ... wet year-round. The areas include marshes, swamps, bogs and ...
Cached Biology News:Mysterious microbe plays important role in ocean ecology 2Mysterious microbe plays important role in ocean ecology 3NPL unveils new equipment to make cancer treatment safer 2Value of satellites recognized for conserving wetlands 2Value of satellites recognized for conserving wetlands 3
(Date:10/1/2014)... , October 1, 2014 ... to software invited to engage around the theme, ,Commercial ...     Elsevier , ... products and services, will host a gathering of some ... issues and trends impacting healthcare today and in the ...
(Date:9/30/2014)... , Sept. 30, 2014 Pacific Northwest ... Summary Global Markets Direct,s, ,Pacific Northwest ... provides an overview of the Pacific Northwest Biotechnology, ... report provides comprehensive information on the current therapeutic ... with comparative analysis at various stages, therapeutics assessment ...
(Date:9/30/2014)... Proove Biosciences , the commercial ... announce a new genetic test built upon research from ... Test will provide physicians with an objective way ... levels are stratified between individuals. With this new test, ... has a genetic predisposition that will affect their pain ...
(Date:9/30/2014)... Genedata, a leading provider ... and related life science research, today announced ... Selector as its host-pathogen data analysis platform ... a European consortium dedicated to improving the ... anti-fungal drug therapies. Genedata Selector supports this ...
Breaking Biology Technology:Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 2Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 3Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 2Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 3Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 2FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 3
... DIEGO, Jan. 29 BioMed Realty Trust, Inc.,(NYSE: BMR ... quarter,and year ended December 31, 2007 after the market closes ... Chief Executive Officer, and Kent Griffin,Chief Financial Officer, will host ... February 29, 2008 to discuss the company,s,financial results and operations ...
... Jan. 29 QED International Associates, Inc,administrator ... 20 underlying,indexes for the HealthShares(TM) Exchange-Traded Funds, ... trading on Thursday January 31, 2008 KV,Pharmaceutical ... (Nasdaq: ARXT ) in the HealthShares(TM) ...
... to be Highlighted at Molecular Imaging Conference, ... Inc., (OTC Bulletin Board: IMDS) a pioneer in ... 2008, January 28 - 31,2008, in Dubai, United ... CD89., (Logo: http://www.newscom.com/cgi-bin/prnh/20040412/IMDSLOGO ), ...
Cached Biology Technology:BioMed Realty Trust To Report 2007 Fourth Quarter and Year-End Results 2QED International Associates Announces Changes to the HealthShares(TM) Composite and HealthShares(TM) Respiratory/Pulmonary Indexes 2Imaging Diagnostic Systems Exhibits at Major Middle East Health Conference 2Imaging Diagnostic Systems Exhibits at Major Middle East Health Conference 3
Mouse polyclonal antibody raised against a partial recombinant TSEN2. NCBI Entrez Gene ID = 80746...
Mouse polyclonal antibody raised against a partial recombinant AGTRAP. NCBI Entrez Gene ID = 57085...
Mouse monoclonal antibody raised against a partial recombinant RAB11B. NCBI Entrez Gene ID = RAB11B...
... Mouse polyclonal antibody raised against ... Immunogen: SF3B2 ... a.a) partial recombinant protein with ... Accession Number: NM_006842 ...
Biology Products: