Navigation Links
Early exposure to insecticides gives amphibians higher tolerance later
Date:7/29/2013

PITTSBURGH -- Amphibians exposed to insecticides early in lifeeven those not yet hatchedhave a higher tolerance to those same insecticides later in life, according to a recent University of Pittsburgh study.

Published in Evolutionary Applications, the Pitt study found that wood frog populations residing farther from agricultural fields are not very tolerant to a particular type of insecticide, but they can become more tolerant with early exposure.

"This is the first study to show that tadpole tolerance to insecticides can be influenced by exposure to insecticides extremely early on in lifein this case, as early as the embryonic stage," said study principal investigator Rick Relyea, Pitt professor of biological sciences within the Kenneth P. Dietrich School of Arts and Sciences and director of the University's Pymatuning Laboratory of Ecology.

"Amphibian populations are declining worldwide, and pesticides and insecticides are one hypothesized cause," said Jessica Hua, lead author of the paper and a PhD candidate studying biological sciences in Relyea's laboratory. "So this discovery has promising implications for the persistence of amphibian populations."

The Pitt teamwhich also included Nathan Morehouse, Pitt assistant professor of biological sciencesexamined three potential factors that might allow larval wood frogs to have a high tolerance to the insecticide: the concentration of the initial insecticide exposure, the timing of the exposure, and the population's history of exposure. They chose to work with carbaryl, a popular household insecticide that also is used for malaria prevention.

The researchers conducted experiments with both embryos and hatchlings that were collected as newly laid eggs from four Pennsylvania pondstwo near agricultural fields and two farther away. Both embryos and hatchlings from all four environs were first exposed to a low, nonlethal concentration of the insecticide. Later, they exposed the same individuals to a lethal concentration of the insecticide at the tadpole stage and measured the tadpoles' mortality rates over the course of several weeks.

Next, the team wanted to observe whether insecticide tolerance played a role in the frogs' acetylcholinesterase (AChE), a key enzyme in the nervous system of animals. Carbaryl is known to bind itself to this AChE enzyme in frogs, causing their nervous systems to slow. The Pitt team measured the concentration of total tadpole AChE in a sample of tadpole bodies, finding that low exposure levels of carbaryl stimulated the tadpoles to produce greater amounts of the enzymemaking them more tolerant to the insecticide later in life.

The team is now examining whether exposure to an insecticide early in life can make amphibians more tolerant to other insecticides.

"In other words, we are asking if a tolerance to one insecticide can convey cross tolerance to other insecticides that affect the nervous system similarly," said Hua.


'/>"/>

Contact: B. Rose Huber
rhuber@pitt.edu
412-624-4356
University of Pittsburgh
Source:Eurekalert

Related biology news :

1. Antiepileptic drug use while pregnant impacts early child development
2. Early life and in utero factors found to influence testicular function in adulthood
3. Light and nanoprobes detect early signs of infection
4. New data on islet autoantibodies in young children defines early type 1 diabetes development
5. Pearly perfection
6. Herbal extract boosts fruit fly lifespan by nearly 25 percent, UCI study finds
7. NIH awards UCI $10 million to study early-life origins of adolescent mental disorders
8. Early exposure to bisphenol A might damage the enamel of teeth
9. Autism discovery paves way for early blood test and therapeutic options
10. Turning point for early human diets occurred 3.5 million years ago
11. JCI early table of contents for May 24, 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/6/2017)... -- Forecasts by Product Type (EAC), Biometrics, ... (Transportation & Logistics, Government & Public Sector, Utilities / ... Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), Hospitality ... looking for a definitive report on the $27.9bn Access ... ...
(Date:4/4/2017)... YORK , April 4, 2017   EyeLock ... today announced that the United States Patent and Trademark ... patent broadly covers the linking of an iris image ... same transaction) and represents the company,s 45 th ... latest patent is very timely given the multi-modal biometric ...
(Date:3/30/2017)... 30, 2017 Trends, opportunities and forecast in ... by technology (fingerprint, AFIS, iris recognition, facial recognition, hand ... by end use industry (government and law enforcement, commercial ... banking, and others), and by region ( North ... Asia Pacific , and the Rest of ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... multicenter, prospective clinical study that demonstrates the accuracy of the FebriDx® test, ... clinically significant acute bacterial and viral respiratory tract infections by testing the ...
(Date:10/12/2017)... ... ... AMRI, a global contract research, development and manufacturing organization ... quality of life, will now be offering its impurity solutions as a stand-alone ... for all new drug products, including the finalization of ICH M7 earlier this ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO and ... Labs ), Inc. has been selected for membership in ARCS Alumni Hall ...
(Date:10/11/2017)... ... ... eye wash is a basic first aid supply for any work environment, but most personal ... rinse first if a dangerous substance enters both eyes? It’s one less decision, and likely ... dual eye piece. , “Whether its dirt and debris, or an acid or alkali, getting ...
Breaking Biology Technology: