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Early exposure to bisphenol A might damage the enamel of teeth
Date:6/10/2013

Analysis of the damage shows numerous characteristics that are common with a recently identified pathology of tooth enamel that affects roughly 18% of children between the ages of 6 and 8.

These results have been published in the American Journal of Pathology.

Bisphenol A (BPA) is a chemical compound used in the composition of plastics and resins. It is used for example to manufacture food containers such as bottles or babies' bottles. It is also used for the protective films inside drinks cans and food tins, or as developers on sales receipts. Significant amounts of BPA have also been found in human blood, urine, amniotic liquid and placentas. Recent studies have shown that this industrial compound has adverse effects on the reproduction, development and metabolism of laboratory animals. It is strongly suspected of having the same effects on humans.

As a precautionary measure, the manufacture and commercialisation of babies' bottles containing bisphenol A were prohibited in Europe in January 2011. The prohibition will be extended to all food containers in France as from July 2015.

So this study shows that teeth are the latest in an already long list of victims of BPA. The Inserm researchers have shown that the incisors of rats treated with low daily doses of BPA (5 microgrammes/kg/day) could be damaged by this. This effect has also been observed within a development window of no more than 30 days post-birth in rats, thus demonstrating a range of sensitivity to exposure.

Analysis of these teeth showed numerous characteristics that are common with a tooth enamel pathology known as MIH (Molar Incisor Hypomineralisation) that selectively affects first molars and permanent incisors. This enamel pathology is found in roughly 18% of children between the ages of 6 and 8. Children affected by this pathology present with teeth that are hypersensitive to pain and liable to cavities. It is interesting to note that the
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Contact: Sylvie Babajko
sylvie.babajko@crc.jussieu.fr
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert

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