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Early administration of antiretroviral therapy can improve survival
Date:4/9/2009

inalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum" target="_blank">NEJM) published identical results this month, obtained by a North American study that also involved many cohorts (NA-ACCORD). The findings of these studies will be key to helping doctors throughout the world to decide on the best time to begin antiretroviral treatment.

The Catalan and Balearic cohort PISCIS (Project for the Computerization and Clinical Epidemiological Monitoring of HIV Infection and AIDS) was created in 1998 and is currently monitoring more than 10,000 patients. Nine Catalan hospitals are taking part: Hospital Clnic, Barcelona; Hospital Universitari Germans Trias i Pujol; Hospital de Bellvitge; Corporaci Parc Taul de Sabadell; Hospital de Matar; Hospital General de Vic; Hospital de Palams; Hospital General de l'Hospitalet; and Hospital Alt Peneds de Vilafranca. A Balearic hospital, the Son Dureta hospital in Mallorca, is also taking part and the CEEISCAT is acting as the coordinating center.

The PISCIS project, which is funded by the Department of Health and the FIPSE, has already provided important local responses to questions such as survival of infected patients, effectiveness of antiretroviral therapies and the best time to begin treatment. The study published in The Lancet confirms the findings that PISCIS had already published based on Catalan and Balearic data in the journal JAIDS (J Acquir Immune Defic Syndr. 2008; 47(2):212-20), suggesting that the minimum CD4 count for beginning treatment is at the threshold of 350 cells/L. The Department of Health aims to potentiate this project so that it covers the largest possible number of Catalan hospitals and serves not only for clinical
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Contact: lex Argem
aargemi@clini.ub.es
34-932-275-700
IDIBAPS - Institut d'Investigacions Biomdiques August Pi i Sunyer
Source:Eurekalert

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