Navigation Links
ESF EURYI award winner aims to stop cancer cells reading their own DNA
Date:8/13/2007

ents of the machinery are responsible for slicing and assembling the DNA itself. All of these are potential targets for anti-cancer therapy, providing it is possible to single out the tumor cells. Most existing chemotherapy targets all dividing cells, and the aim to find more sensitive techniques.

However Dekkers work is not just confined to cancer, having the broader goal within the ESF EURYI project of unraveling the underlying physical principles behind these molecular motors that operate at the nanometer scale to process and manipulate the information stored within the DNA and RNA of our cells. Dekker is exploiting a variety of new highly sensitive manipulation and imaging techniques capable of resolving single molecules. These include force spectroscopy, new forms of optical microscopy with greatly improved resolving power and field depth, as well as nanotechnologies. The research involves cross-disciplinary work among scientists in different fields with the long term goal of developing more precisely targeted molecular medicines for a variety of diseases involving disruption to normal cellular functions and not just cancer.

Dekkers work has already shown great promise, and she has been able to predict what effect certain antitumor drugs would have on the basis of her molecular insights, confirming her hypotheses in yeast cells. Indeed the work with antitumor drugs is, as far as I know, the first experiment in which single-molecule experiments have resulted in a prediction for a cellular effect, said Dekker.


'/>"/>

Contact: Thomas Lau
tlau@esf.org
33-388-762-158
European Science Foundation
Source:Eurekalert

Page: 1 2

Related biology news :

1. NJIT Presidential Award winner takes stem cell research another step
2. TGen awarded $7.1 million to accelerate brain disease research
3. Virtual microscopy project wins educational technology award
4. On a flys wing, scientists tally evolutions winners and losses
5. Viral DNA sequence a possible trigger for breast cancer
6. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
7. Jump-starting T Cells In Skin Cancer
8. Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
9. Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer
10. Its not all genetic: Common epigenetic problem doubles cancer risk in mice
11. Columbia research lifts major hurdle to gene therapy for cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... VIEW, Calif. , Feb. 3, 2015 /PRNewswire/ ... printer technology, demand from industries such as consumer ... global market for surface mount technology (SMT) screen ... equipment to automatic control will push the adoption ... dispensers will remain steady as glue dispensers are ...
(Date:1/22/2015)... , Jan. 9, 2015 Valid S.A. ("Company") (BM&FBOVESPA: VLID3 ... in general the State of Washington,s ... a new enrollment and central issuance system for driver,s licenses ... The project planning and development will start in January ...
(Date:1/22/2015)... , Jan. 13, 2015  Today, FreeWavz ( www.FreeWavz.com ... its crowdfunding campaign on Fundable, https://www.fundable.com/freewavz . ... of production capacity to meet customer demand. ... - http://photos.prnewswire.com/prnh/20150113/168790 Invented ...
Breaking Biology News(10 mins):End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3Valid USA Signs Contract For Washington Driver's License Issuance 2FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2
... release is available in Spanish . , Agricultural ... wheat straw into ethanol "gold," and learning more about the ... production. At the ARS National Center for Agricultural ... conducted a 5-year study that examined whether wheat straw--a crop ...
... WASHINGTON, DC Fascinating advances across the spectrum ... be featured and explained through engaging table-top exhibits ... 16th Annual Exhibition and Reception. The exhibition/reception will ... Wednesday, April 14, in Rooms B338-340 of the ...
... old excuse, "I am only overweight because of my ... more evidence that the way our bodies digest and ... for every person. The budding discipline of metabolomics strives ... scientists and food chemists at the Technische Universitaet Muenchen ...
Cached Biology News:Cellulosic ethanol: Expanding options, identifying obstacles 2Science returns to Capitol Hill spotlight at April 14 exhibition 2Science returns to Capitol Hill spotlight at April 14 exhibition 3Science returns to Capitol Hill spotlight at April 14 exhibition 4Metabolic fingerprints offer fresh clues and a new path toward personalized medicine 2Metabolic fingerprints offer fresh clues and a new path toward personalized medicine 3
(Date:2/26/2015)... IL (PRWEB) February 26, 2015 Already ... its gauging line by expanding its Length Gauge offerings ... ACANTO gauges. , Specifically, HEIDENHAIN’s pencil probe-style ... improved force specification. Two new 1Vpp, 12mm stroke ... lower force applications. One is a variant with a ...
(Date:2/26/2015)... February 26, 2015 According to a ... Biotechnology Market For Transgenic Crops (Corn, Soybean, Cotton and ... Analysis, Size, Share, Growth, Trends and Forecast, 2013 – ... 15,300 million in 2012 and is expected to reach ... of 9.5% from 2013 to 2019. , Demand ...
(Date:2/26/2015)... Feb. 26, 2015 Ceres, Inc . ... in Oracle PartnerNetwork. In attaining Gold Level membership, Ceres ... establish Oracle-related knowledge in delivering Ceres, Persephone genome visualization ... customers. Originally developed for in-house use by ... in and out of massive amounts of genetic data, ...
(Date:2/26/2015)... WOODLANDS, Texas , Feb. 26, 2015   Lexicon ... that Lexicon management will present at the Cowen 35 th ... at 8:40 a.m. EST in Boston . ... programs and milestones. A webcast of the presentation ... An archived version of the presentation will be available at ...
Breaking Biology Technology:Accuracy and Versatile Gauging Go Hand in Hand at HEIDENHAIN 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4Lexicon To Present At The Cowen 35th Annual Health Care Conference 2
... Motor Vehicles in Wisconsin plans to close all its offices ... upgrade. The new system, which has been in development for ... make searches faster and add newer programming languages. Employee training ... next day. , ,The existing system has been in place ...
... Wis. The city of Madison is asking for bids ... on Friday. , ,The vendor would be able to charge user ... including fees to the city, county and state for the right ... However, mayoral spokesperson George Twigg said plans and costs are still ...
... Madison, Wis. While the Madison chapter ... looking ahead for new social and technological developments, Scott Converse ... important if they want to see where the next big ... at the UW-Madison School of Business and founder of the ...
Cached Biology Technology:Madison asks for wireless bids; airport, downtown would be first 2Business-school IT director points to reasons for wireless trend 2