Navigation Links
ERC Starting Grant for the researcher of kidney diseases
Date:9/11/2009

The European Research Council (ERC) expects to fund some 240 top researchers in its second prestigious ERC Starting Grant competition. This new wave of grantees follows the 299 researchers who received grants in the first Starting Grant competition in 2007.

In total, 2503 proposals were submitted to the second Starting Grant call.

Sanna Lehtonen's research group is studying the kidney glomerular ultrafiltration in both health and under pathological conditions, concentrating especially on studying the development of albuminuria that is an indicator of kidney disease. "Specifically, we are interested in the pathophysiological mechanisms leading to the development of diabetic nephropathy, a serious complication of diabetes", Lehtonen says.

Up to one third of diabetic patients develop nephropathy. Microalbuminuria is the earliest sign of the complication, which may ultimately develop into end-stage renal disease requiring dialysis or a kidney transplant. Insulin resistance has been associated with an increased risk for diabetic nephropathy. "Interestingly, glomerular epithelial cells or podocytes have recently been found to be insulin responsive and to increase their glucose uptake upon insulin stimulation. It has also been shown that intact filamentous actin cytoskeleton is required for the insulin response. Our studies concentrate on analyzing the role of insulin signaling and glucose transport and the regulation of actin cytoskeleton in podocytes thereby aiming to define the mechanisms leading to perturbations in the kidney ultrafiltration function and development of albuminuria", Lehtonen tells.

The aim of Lehtonen's ERC project called DiaDrug is to clarify the mechanisms leading to the development of insulin resistance in podocytes and to study the association between insulin resistance and the development of albuminuria. The researchers will develop transgenic zebrafish and mouse models to study the role of proteins assoc
'/>"/>

Contact: Sanna Lehtonen
sanna.h.lehtonen@helsinki.fi
358-503-410-036
University of Helsinki
Source:Eurekalert

Page: 1 2

Related biology news :

1. IGC scientist awarded prestigious European Research Council Starting grant
2. Urea tanks on diesel trucks -- thats the law in the United States starting in 2010
3. Starting university may be hazardous to your health: study
4. Barrow scientist awarded $400,000 grant to study cell associated with intuition and autism
5. UC Riverside research on barley genome gets boost from $1 million USDA grant
6. NC State receives NSF grant to discover plant switchboards
7. UTs Valentin Dragoi gets $1.2 million grant for groundbreaking approach to brain research
8. Idaho researchers win grant to explore DNA frontier
9. USDA grant to educate AIDS patients about food safety
10. Iowa State faculty attract $4.8 million in American Recovery and Reinvestment Act grants
11. UOG scientists successfully compete for research grants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/18/2015)... As mobile payments become more prevalent ... and apps continue to be introduced into the market place ... payment industry in focus today are:  NXT-ID, Inc. (NASDAQ: ... BABA ), Apple Inc. (NASDAQ: AAPL ), Google ... FB ) NXT-ID, Inc. (NASDAQ: ...
(Date:3/16/2015)... , March 16, 2015 ... GmbH will present groundbreaking innovations in biometric identification ... Germany .      (Photo: ... biometric innovation is well at the forefront: the ... e-gate made in Germany . ...
(Date:3/12/2015)... , March 12, 2015 WHEN:Tuesday, March ... Registration here: http://bit.ly/1G7Os0L . SPEAKERS: , Frost ... SeshagiriPhoto - http://photos.prnewswire.com/prnh/20150311/181111 Biometric ... to compete in several different markets and industries. ... currently witnessing an uptrend. Join ...
Breaking Biology News(10 mins):Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3
... BOSTON--A section of the AIDS virus,s protein envelope once considered ... one of the most promising, new research by Dana-Farber Cancer ... protein known as the V3 loop, is an attractive vaccine ... offer protection against multiple genetic subtypes of HIV-1, the virus ...
... NEW YORK, March 31, 2011 Hoyos Group ... Chief Marketing Officer, effective April 1, 2011. ... a member of Hoyos Group,s senior executive team, ... marketing, strategic business development, brand strategy, positioning and ...
... small block of aluminum with a tiny groove carved ... Institute of Standards and Technology (NIST) and the Polytechnic ... "green chemistry" method for making biodegradable polymers. Their recently ... of microfluidics, a technology more commonly associated with inkjet ...
Cached Biology News:Study identifies promising target for AIDS vaccine 2Study identifies promising target for AIDS vaccine 3Hoyos Group Appoints Anthony Antolino as Chief Marketing Officer 2Hoyos Group Appoints Anthony Antolino as Chief Marketing Officer 3Microreactors: Small scale chemistry could lead to big improvements for biodegradable polymers 2
(Date:3/27/2015)... New York (PRWEB) March 27, 2015 ... the 2015 application period for 43North - the world’s ... prizes, including a grand prize of $1 million, six ... entrepreneurs from around the world to compete for prizes ... funded enterprises in the Western New York region. ...
(Date:3/26/2015)... CA (PRWEB) March 26, 2015 PRC ... (CRO), announced today several management and executive appointments effective ... Chief Financial Officer (CFO) and member of the Board ... of Business Operations, and Sue Dowden will assume the ... co-founder and current Chief Operations Officer (COO), has been ...
(Date:3/26/2015)... The Market Element LLC, a leading ... with Designing Gig LLC to provide website design, development, ... “Forging this alliance with Designing Gig represents a pivotal ... a comprehensive, end-to-end, digital solution for our clients, which ... Chuck Miller, president of The Market Element. “For small ...
(Date:3/26/2015)... and CINCINNATI , March ... (LSE: SHP, NASDAQ: SHPG ) and Cincinnati ... broad research collaboration for rare diseases. The goal of ... therapies to treat rare diseases with high unmet ... with Cincinnati Children,s research expertise. As a nationally ...
Breaking Biology Technology:Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 2Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 3Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 4Governor Andrew M. Cuomo Anounces Launch of Year Two of World's Largest Business Idea Competition and Opening of New Incubator Space in Buffalo, New York 5PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 2PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 3The Market Element LLC and Designing Gig LLC Form Strategic Alliance 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 3Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 4Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 5
... Nov. 12 VIA Pharmaceuticals,(Nasdaq: VIAP ... development of,compounds for the treatment of cardiovascular ... advisory board. Joining the clinical advisory,board,s chair, ... Medicine,Harvard Medical School, and Senior Physician, Brigham ...
... Conditions in Patients Who are Already Taking Opioid ... ... 12 Cephalon, Inc. (Nasdaq:,CEPH) today announced it has submitted a ... (FDA) seeking approval to,market FENTORA(R) (fentanyl buccal tablet) [C-II] for the ...
... The Edwin A. Stevens Society of Stevens Institute of Technology ... Systems and Enterprises, Dr. Dinesh Verma, with the Presidents Leadership ... Park Avenue Club in Florham Park, N.J., Nov. 10, beginning ... invitation only., The Presidents Leadership Award is presented to a ...
Cached Biology Technology:VIA Pharmaceuticals Expands Clinical Advisory Board With Leading Experts in Cardiovascular Disease 2VIA Pharmaceuticals Expands Clinical Advisory Board With Leading Experts in Cardiovascular Disease 3VIA Pharmaceuticals Expands Clinical Advisory Board With Leading Experts in Cardiovascular Disease 4Cephalon Submits Supplemental New Drug Application for FENTORA 2Cephalon Submits Supplemental New Drug Application for FENTORA 3Cephalon Submits Supplemental New Drug Application for FENTORA 4Cephalon Submits Supplemental New Drug Application for FENTORA 5Cephalon Submits Supplemental New Drug Application for FENTORA 6Cephalon Submits Supplemental New Drug Application for FENTORA 7Dr. Dinesh Verma to be honored with President's Leadership Award at Edwin A. Stevens Society Gala 2Dr. Dinesh Verma to be honored with President's Leadership Award at Edwin A. Stevens Society Gala 3
... Blunt-Ended PCR Cloning Kit, 40 reactions. ... cloning of all PCR products with ... cloning approaches by offering consistently better ... 25-fold more positive clones.Amplicons generated by ...
PCR System for increased fidelity, yield and length of PCR products. Amplifies targets up to 10 kb from human genomic DNA....
... Peptide sequences: Two separate vials ... to the same sequence used as ... (Catalog No. 160890) ... Cayman's guanylate cyclase polyclonal antiserum (Catalog ...
...
Biology Products: