Navigation Links
EPA reviews Univ. of Michigan dioxin study
Date:10/1/2009

(CHICAGO - Sept. 30, 2009) U.S. Environmental Protection Agency's Office of Research and Development has completed its review of a dioxin exposure study conducted by the University of Michigan in the Midland-Saginaw, Michigan area. EPA found the study was conducted well and provided useful, scientifically credible information. However, the study is of limited value to help EPA fully evaluate human exposure to levels of dioxin in the Tittabawassee River and Saginaw River and Bay.

EPA's review was conducted under the dioxin science plan announced by Administrator Lisa P. Jackson this past May. The University of Michigan Dioxin Exposure Study (UMDES) was conducted in response to community concerns that dioxin compounds from the Midland-based Dow Chemical Co. had contaminated the city and surrounding areas. The University received financial support for the UMDES from Dow through an unrestricted grant. Primary data collection was completed in 2004-2005 and the analysis of study results continues.

EPA's review identified several significant issues that limit the utility of the UMDES results:

The study did not include children, who tend to have higher exposures to contaminants because they have more contact with, and ingestion, of soils and dusts.

It is unclear if the study included a sufficient number of properties with highly-contaminated soils. Such properties can be found in the Midland-Saginaw area.

It is uncertain how well the study represented people who participate in activities that could lead to elevated dioxin exposures, such as eating local fish and game with elevated dioxin levels.

Additionally, the UMDES included no health status information on the people surveyed. Thus, the UMDES data do not support analysis of the association between dioxin blood levels and possible health effects. Understanding these issues is critical when evaluating associations between exposure and blood dioxin levels in sensitive populations, including children. Also, the site specific data collected by the study will not be relevant as EPA revises its national interim preliminary remediation goals for dioxin in soil.

The study included more than 900 participants and provided estimates of the distributions of dioxin concentrations in blood, soil and dust in the Midland-Saginaw area as well as a reference area for comparison 100 miles to the south. EPA's review found that the UMDES was well-suited to identify patterns of serum dioxin, furan and PCB levels among adults. Among the study's other findings: people living the Midland-Saginaw area have higher blood dioxin levels than those in the reference area and national averages, and that properties in Midland-Saginaw tend to have higher soil dioxin levels than in the reference area. As has been found in other studies, it also found that higher blood dioxin levels were associated with demographic factors such as increased age, dietary choices and being overweight.

Representatives from EPA's Office of Research and Development and Office of Solid Waste and Emergency Response will hold a public meeting in the Midland-Saginaw area in late October to discuss the UMDES review. More information will be announced soon.


'/>"/>

Contact: Mick Hans
hans.mick@epa.gov
312-353-5050
U.S. Environmental Protection Agency
Source:Eurekalert

Related biology news :

1. Reviews of microbial gene language published in special issue of Trends in Microbiology
2. Biophysical Reviews makes debut in 2009
3. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
4. Univ. of Arizona receives $2.5 million to study Amazon forests and climate change
5. Michigan Tech scientists identify genes linked to Lou Gehrigs disease
6. Climate change driving Michigan mammals north
7. University of Michigan installs second Genomatix Genome Analyzer
8. Lake Michigan fish populations threatened by decline of tiny creature
9. Michigan Tech researchers link 11 genetic variations to type 2 diabetes
10. Dioxins in food chain linked to breastfeeding ills
11. Dioxin risk in soil and plant tissues after long-term biosolids application
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2016)... UAE, April 20, 2016 The ... as a compact web-based "all-in-one" system solution for all ... fingerprint reader or the door interface with integration authorization ... access control systems. The minimal dimensions of the access ... into the building installations offer considerable freedom of design ...
(Date:4/14/2016)... April 14, 2016 BioCatch ... Detection, today announced the appointment of Eyal Goldwerger ... role. Goldwerger,s leadership appointment comes at a ... of the deployment of its platform at several of ... technology, which discerns unique cognitive and physiological factors, is ...
(Date:3/31/2016)... R.I. , March 31, 2016  Genomics firm ... of founding CEO, Barrett Bready , M.D., who ... members of the original technical leadership team, including Chief ... President of Product Development, Steve Nurnberg and Vice President ... returned to the company. Dr. Bready served ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... -- Global demand for enzymes is forecast to grow ... billion.  This market includes enzymes used in industrial ... animal feed, and other markets) and specialty applications ... beverages will remain the largest market for enzymes, ... containing enzymes in developing regions.  These and other ...
(Date:6/27/2016)... 2016  Sequenom, Inc. (NASDAQ: SQNM ), ... through the development of innovative products and services, announced ... United States denied its petition to review ... Sequenom,s U.S. Patent No. 6,258,540 (",540 Patent") are not ... the Supreme Court,s Mayo Collaborative Services v. Prometheus Laboratories ...
(Date:6/27/2016)... CA (PRWEB) , ... June 27, 2016 , ... ... for clinical trials, announced today the Clinical Reach Virtual Patient Encounter CONSULT ... care circle with the physician and clinical trial team. , Using the CONSULT module, ...
(Date:6/27/2016)... ... June 27, 2016 , ... Rolf ... join the faculty of the University of North Carolina Kenan-Flagler Business School ... and entrepreneurship at UNC Kenan-Flagler, with a focus on the school’s international efforts, ...
Breaking Biology Technology: