Navigation Links
EASL publishes first European Clinical Practice Guidelines for Wilson's disease
Date:2/7/2012

Geneva, Switzerland: The first European Clinical Practice Guidelines (CPGs) for the diagnosis and management of Wilson's disease are published today by the European Association for the Study of the Liver (EASL) on the EASL website -- www.easl.eu.(1) Developed to assist physicians and healthcare providers in the clinical decision making process, the guidelines describe best practice for the diagnosis and treatment of patients with Wilson's disease -- a rare genetic(2) disorder that, if left untreated, is fatal.

Approximately one in 30,000 people worldwide are affected by Wilson's disease -- a condition in which copper is not excreted by the body effectively, leading to excess copper build up, liver failure and damage to the brain. While Wilson's disease may manifest at any age, the majority of patients present between the ages of 5 and 35.

Lead author Professor Peter Ferenci said: "The clinical presentation of Wilson's disease can vary widely, but it must be considered in any patient who presents with a combination of unexplained liver disease and neurological or neuropsychiatric disorders. In the absence of Kayser-Fleischer rings(3) -- which are typical, but not always present -- the guidelines recommend measurement of urinary copper excretion and hepatic parenchymal copper as diagnostic methods of choice. Notably, age alone should not be the basis for eliminating a diagnosis of Wilson's disease."

The CPGs, based on a systematic review of existing literature, provide best practice diagnosis and treatment protocols with an emphasis on:

  • Clinical presentation and prognosis
  • Diagnostic strategies (e.g. serum ceruloplasmin, basal 24-hour urinary copper excretion, genetic analysis)
  • Importance of family screening
  • Treatment options (e.g. chelating agents, zinc, liver transplantation)

With treatment, prolonged survival has become the norm for Wilson's disease patients. The g
'/>"/>

Contact: Travis Taylor
easlpressoffice@cohnwolfe.com
44-207-331-5472
European Association for the Study of the Liver
Source:Eurekalert

Page: 1 2

Related biology news :

1. Elseviers Maturitas publishes position statement on the role of vitamin D in postmenopausal women
2. Bulletin of the Atomic Scientists publishes Japanese translation of special Fukushima issue
3. Dr. Michael Collins publishes paper on ivory-billed woodpecker
4. ESHRE publishes English textbook for paramedics
5. Census of Marine Life publishes historic roll call of species in 25 key world areas
6. Nano Letters publishes Dr. Yong Shis energy harvesting technology
7. NASA scientist publishes new book: Coming Climate Crisis? Consider the Past, Beware the Big Fix
8. Endangered Species Research publishes theme section on biologging science
9. International Biometric Society co-publishes journal with Springer
10. AIBS publishes Darwin articles open access
11. JAX publishes online tool for exploring autoimmune disease gene networks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... Canada , April 17, 2015 ... growing security concerns, and technological advancement to drive ... until 2020   According ... Saudi Arabia Biometric Systems Market Forecast &  Opportunities, 2020 ", biometric systems ... is projected to register growth at CAGR of ...
(Date:4/14/2015)...  HYPR Corp. today announced it has joined ... tm , an industry consortium transforming online authentication ... technology and collaborate to deliver open specifications for ... and private, and easier to use. ... sensitive user information and eliminates the dependency on ...
(Date:4/14/2015)... Conn. , April 14, 2015 NXT-ID, ... a biometric authentication company focused on the growing mobile ... been nominated for the 2015 New York Design Awards ... The Design100, New York City Design Awards are part ... based on over 2,500 ratings from the marketplace, industry ...
Breaking Biology News(10 mins):Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3
... Meeting of the Southeastern Branch of the Entomological ... 3-6, 2013 at the Hilton Baton Rouge (201 ... entomologists from Alabama, Arkansas, Florida, Georgia, Louisiana, Mississippi, ... to discuss citrus greening disease, invasive species, rice ...
... of living tissues, diseased organs and tumors inside the body ... peer down to the level of atoms? Doctors could make ... a strand of DNA, watching molecules misfold, or identifying a ... Carlos Meriles, associate professor of physics at The City College ...
... Va. , Feb. 13, 2013 AFCEA,s ... Working Together, Keeping the Nation Safe", will be ... Washington, D.C. , February 26-28, 2013.  Attendees ... managers involved in operations, policy and procurement. Additionally, ...
Cached Biology News:Team creates MRI for the nanoscale 2AFCEA's Homeland Security Conference Returns To Washington, D.C. 2
(Date:4/16/2015)... 2015 Spirax Sarco, the leader ... their newly designed, state-of-the-art website in the first ... effectively promotes the Spirax Sarco brand, company capabilities, ... that a site visitor might be looking for ... industries serviced, the latest company news, careers, and ...
(Date:4/16/2015)... Cambridge Semantics , the ... Semantic Web technology, and Informa , the ... for the academic and scientific, professional and commercial ... ‘Smart Data Lake for Clinical Trial and Competitive ... Bio-IT ‘Best of Show’ Award. , The ...
(Date:4/16/2015)... FL (PRWEB) April 16, 2015 ... cap distribution and physician network in Europe and ... company has appointed Fernando Bermúdez, former Business Development ... , An industry veteran, Mr. Bermúdez’s professional achievements ... 75% in Spain, while also penetrating the Portuguese ...
(Date:4/16/2015)... 2015  Schulman Associates IRB, Inc., the industry-leading central ... long-term lease on Laboratory Drive in the heart of ... The location will house review board and service staff, ... reviews and customer service to clients. ... in the deal, while Capital Associates Management, LLC represented ...
Breaking Biology Technology:Spirax Sarco website has a new look 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 3Capillus, LLC Extends Laser Hair Therapy Products to Europe and Asia 2Schulman IRB to Open Office in Research Triangle Park, N.C. 2
... Cell Therapeutics, Inc.,(CTI) (Nasdaq and MTA: CTIC) will ... October 3, 2008. The investor day will provide an ... milestones,for the Company. Additionally, Alessandro Gianni, M.D., Director of ... of Milan,who has authored over 300 publications will be ...
... Cadence Pharmaceuticals,Inc. (Nasdaq: CADX ), a ... proprietary product candidates principally,for use in the ... and CEO Theodore Schroeder will present the ... 1:30pm Eastern Time (10:30am Pacific Time),during the ...
... Sept. 29 RainDance,Technologies announced today the ... conducted with sanofi-aventis, Paris (EURONEXT: SAN and,NYSE: ... France, to develop,the next generation of high-throughput ... was founded with the assistance of the ...
Cached Biology Technology:Cell Therapeutics Provides Details on Investor & Media Day to be Held in Milan, Italy on Friday, October 3, 2008 2Cadence Pharmaceuticals' CEO Theodore Schroeder to Present at the JMP Securities Third Annual Healthcare Focus Conference 2RainDance Technologies Signs a Collaboration Agreement with sanofi-aventis and Louis Pasteur University to Launch dScreen Consortium within ALSACE BIOVALLEY cluster 2RainDance Technologies Signs a Collaboration Agreement with sanofi-aventis and Louis Pasteur University to Launch dScreen Consortium within ALSACE BIOVALLEY cluster 3RainDance Technologies Signs a Collaboration Agreement with sanofi-aventis and Louis Pasteur University to Launch dScreen Consortium within ALSACE BIOVALLEY cluster 4RainDance Technologies Signs a Collaboration Agreement with sanofi-aventis and Louis Pasteur University to Launch dScreen Consortium within ALSACE BIOVALLEY cluster 5