Navigation Links
Dyslexia-linked genetic variant decreases midline crossing of auditory pathways
Date:2/1/2012

Finnish scientists have found that a rare dyslexia-linked genetic variant of the ROBO1 gene decreases normal crossing of auditory pathways in the human brain. The weaker the expression of the gene is, the more abnormal is the midline crossing. The results link, for the first time, a dyslexia-susceptibility gene to a specific sensory function of the human brain. This collaborative study between Aalto University and University of Helsinki in Finland and the Karolinska Insitutet in Sweden was published in the Journal of Neuroscience.

According to previous animal studies, dysfunction of the Robo1 gene prevents normal midline crossing of neurons during fetal development. Humans with totally dysfunctional ROBO1 gene have not been found. However, dyslexic individuals in a large Finnish family have inherited one poorly functioning copy of the ROBO1 gene. This association between ROBO1 and dyslexia was found already in 2005.

In the present study, the scientists quantified the functional crossing of auditory pathways in ten members of this family, applying a sensitive method based on the recording of weak magnetic fields of the brain (magnetoencephalography, MEG). The functional crossing of auditory pathways was significantly weakened in individuals who carried the dyslexia-linked version of the ROBO1 gene.

Dyslexia is the most common learning disability, affecting roughly 10 per cent of the population in most countries.


'/>"/>
Contact: Satu Lamminmki, MD
satu.lamminmaki@aalto.fi
358-503-442-818
Aalto University
Source:Eurekalert  

Page: 1

Related biology news :

1. Body clock receptor linked to diabetes in new genetic study
2. Genetics study reveals how bacteria behind serious childhood disease evolve to evade vaccines
3. Genetic regulation of metabolomic biomarkers - paths to cardiovascular diseases and type 2 diabetes
4. Study pinpoints genetic variation that raises a risk linked to bisphosphonates
5. BU study finds new genetic loci associated with menopause onset
6. Sweeping genetic analysis of rare disease yields common mechanism of hypertension
7. Ambry Genetics Reports Results from Clinical Diagnostic Exome™ Testing of Three Patients
8. The power of flowers: Research sprouts a closer look at sunflower genetics
9. Simpler times: Did an earlier genetic molecule predate DNA and RNA?
10. Scientists refute Greenpeace claim that genetically modified corn caused new insect pest
11. Identifying sloth species at a genetic level
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Dyslexia-linked genetic variant decreases midline crossing of auditory pathways
(Date:8/23/2017)... Aug. 23, 2017  The general public,s help is being enlisted in ... that live in and on the human body –and are believed to ... The Microbiome Immunity Project ... microbiome, starting with the gut. The project's goal is to help advance ... IBM ...
(Date:7/20/2017)... Delta (NYSE: DAL ) customers now can use ... Reagan Washington National Airport (DCA). ... Delta launches biometrics to board aircraft at Reagan Washington ... Delta,s biometric boarding pass experience that ... integrated into the boarding process to allow eligible Delta SkyMiles Members who ...
(Date:6/23/2017)... ARMONK, N.Y. and ITHACA, N.Y. ... IBM ) and Cornell University, a leader in dairy ... combined with bioinformatics designed to help reduce the chances ... breaches. With the onset of this dairy project, Cornell ... the Consortium for Sequencing the Food Supply Chain, a ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... , ... AMRI, a global contract research, development and manufacturing ... and quality of life, will now be offering its impurity solutions as a ... requirements for all new drug products, including the finalization of ICH M7 earlier ...
(Date:10/11/2017)... ... October 11, 2017 , ... At its national board meeting ... I. Sheikh, the co-founder, CEO and chief research scientist of Minnesota-based Advanced Space ... membership in ARCS Alumni Hall of Fame . ASTER Labs is a ...
(Date:10/11/2017)... ... 11, 2017 , ... Personal eye wash is a basic first aid supply for any work ... which eye do you rinse first if a dangerous substance enters both eyes? It’s one ... with its unique dual eye piece. , “Whether its dirt and debris, or an ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... will be hosting a Webinar titled, “Pathology is going digital. Is your lab ... digital pathology adoption best practices and how Proscia improves lab economics and realizes ...
Breaking Biology Technology: