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Duke technique is turning proteins into glass
Date:3/17/2010

l processes -- usually freeze-drying -- to protect them from such microbe damage. Drying also avoids the chemical breakdowns that can also occur when proteins are kept in solution. "But in the freeze-drying process itself, some very sensitive biologic drugs can also get damaged," Needham said.

Freeze-drying proteins into solids is also slower and more expensive than glassifying them, he added. And the resulting "flaky" powder is harder to handle than glassified beads.

Glassification "is a fast process," said Gaul, a senior research scientist in Needham's lab. Unlike freeze-drying, "we can dry particles within minutes, if not seconds, and don't need any specialized equipment."


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Contact: Karl Leif Bates
karl.bates@duke.edu
919-681-8054
Duke University
Source:Eurekalert

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