Navigation Links
Drug used to treat skin conditions is a marine pollutant
Date:3/24/2009

Clotrimazole is a common ingredient in over-the-counter skin creams. Recent results from the University of Gothenburg, Sweden, now show that it is associated with major environmental risks.

"The pharmaceuticals and chemicals in everyday use form a mixture in the ocean that has a direct impact on the growth and reproduction of organisms", says scientist Tobias Porsbring.

When Euorpean authorities assess environmental risks, they often do so for one chemical at a time. Recent research, however, shows that the hazardous chemicals that humans spread in the environment do not work alone. Chemicals, drugs and personal-care products that accompany wastewater often end up in the oceans, where they form a "cocktail" of chemicals. This "cocktail-effect" may be more harmful than the individual chemicals alone.

Environmental risks

Scientist Tobias Porsbring at the Department of Plant and Environmental Sciences at the University of Gothenburg has studied natural communities of microalgae along the Swedish west coast. He presents results in his doctoral thesis that show how the use of a common agent against skin fungi, clotrimazole, is associated with major environmental risks.

"The levels of clotrimazole that are measured in the environment affect the synthesis of sterols in the algae, and these are important in several functions in the algal cells. The growth and reproduction of the algae are disturbed. Single-cell microalgae are the fundamental basis of the ocean food chain, and the use of clotrimazole thus may affect the complete ocean ecosystem", says Tobias Porsbring.

"Cocktail effect" on microalgae

Clotrimazole, however, does not act alone in the ocean ecosystem. Many other substances are often found in the oceans, including propranolol (a drug to lower blood pressure), triclosan (an anti-bacterial agent commonly found in soap and deodorants), fluoxetine (an anti-depressant pharmaceutical) and zinc pyrithione (found in anti-dandruff shampoos). The results that Tobias Porsbring presents show that a mixture of such compounds forms a "cocktail effect" that has a direct impact on the growth of the microalgal community.

Theoretical model

The fact that low levels of a pollutant that are insufficient to cause a detectable effect may contribute to a larger, combined effect with other chemicals emphasises that cocktail effects are a real environmental problem. Despite this, assessments of environmental risk are usually carried out on one chemical at a time. Through knowledge of environmental levels and the impact of individual chemicals Tobias Porsbring's thesis launch a theoretical model for calculating how cocktail effects arise. This model can be used to obtain highly reliable estimates of the composite environmental risk from mixtures of chemicals in the ocean ecosystem.


'/>"/>

Contact: Krister Svahn
krister.svahn@science.gu.se
46-031-786-4912
University of Gothenburg
Source:Eurekalert  

Related biology news :

1. Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment
2. Lancet study supports new, highly effective treatment for blood disorder
3. Buckyballs to treat multiple sclerosis
4. Cellular discovery may lead to targeted treatment for rare form of anemia
5. Stem cell infusion and hyperbaric oxygen treatment improve islet function in diabetes
6. Multiple route bone marrow stem cell injections show promise to treat spinal cord injury
7. Interventional treatment can be recommended as first-line treatment for silent killer
8. Freezing kidney cancer: Hot treatment should be new gold standard for destroying small tumors
9. Antibody key to treating variant CJD, scientists find
10. Using hair to manage HIV/AIDS and predict treatment success
11. Research uncovers promising target to treat chronic abdominal pain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug used to treat skin conditions is a marine pollutant
(Date:2/24/2017)...  EyeLock LLC, a leader of iris-based identity ... biometric solution on the latest Qualcomm® Snapdragon™ 835 ... World Congress 2017 (February 27 – March ... 3, Stand 3E10. The Snapdragon ... platform—a combination of hardware, software and biometrics ...
(Date:2/22/2017)... , Feb. 22, 2017 With ... 2021, ABI Research identifies four technologies that innovative ... to secure significant share in the changing competitive ... and passive authentication.   "Companies can ... comes to security," says Dimitrios Pavlakis , ...
(Date:2/21/2017)... N.Y. and PORTLAND, Ore. ... ) and the Avamere Family of Companies (Avamere Health ... today announced a six-month research study that will apply ... improve eldercare at senior living and health centers. By ... Avamere hopes to gain insights into physical and environmental ...
Breaking Biology News(10 mins):
(Date:2/24/2017)... ... February 24, 2017 , ... ... can be safely completed in an ambulatory surgery center (ASC) with satisfactory clinical ... and previous two-year TDR studies. , Jake Lubinski, president of AxioMed, commented ...
(Date:2/24/2017)... ... February 24, 2017 , ... Delpor, Inc. (Delpor), a biotechnology company ... National Institute of Mental Health (NIMH) for the further advancement of the company’s 3-month ... technology and is expected to deliver therapeutic levels of olanzapine for a period of ...
(Date:2/24/2017)... San Diego, Calif. (PRWEB) , ... February 24, 2017 , ... ... African food and wine scene. Making stops in several cities, she gained a ... Her culinary adventure began in Stellenbosch, a town in South Africa’s Western Cape province. ...
(Date:2/24/2017)... KNOXVILLE, Tenn. , Feb. 24, 2017 /PRNewswire/ ... ) ("Provectus" or the "Company"), a clinical-stage oncology ... information regarding the deadline to participate in its ... million units, consisting of shares of common stock ... stockholders and holders of listed warrants. ...
Breaking Biology Technology: