Navigation Links
Drug to fight tumors also fights the flu and possibly other viruses
Date:2/28/2011

Ever get a flu shot and still get the flu? If so, there's new hope for flu-free winters in the years to come thanks to a new discovery by researchers who found that a drug called DMXAA, originally developed as anti-tumor agent, enhances the ability of flu vaccines to ward off this deadly virus. A new research report appearing in the March 2011 issue of the Journal of Leukocyte Biology (http://www.jleukbio.org) suggests that DMXAA could assist flu vaccines by causing the body to produce its own antiviral proteins, called interferons, which interfere with the virus's ability to spread. In addition, DMXAA may be a useful antiviral therapy to treat newly emerging strains of the flu for which a vaccine has not be developed.

"We are hopeful that DMXAA or similar agents can be used ultimately to blunt the impact of yearly influenza outbreaks, and perhaps, for other virus infections as well," said Stefanie Vogel, Ph.D., co-author of the study and Professor of Microbiology and Immunology at the University of Maryland, School of Medicine in Baltimore.

To make this discovery, Vogel and colleagues infected mice with a mouse-adapted influenza strain. When given DMXAA three hours before or after infection and then two days later, the infection was significantly less severe. In addition, they found that DMXAA protected cells from flu strains that are resistant to Tamiflu, one of the most advanced anti-flu drugs on the market. These discoveries suggest that DMXAA could potentially enhance the efficacy of current flu treatments and vaccines, and perhaps treat other viruses or bacteria. To be sure that DMXAA led to increased production of interferons, the researchers also tested it in mice that lacked a gene needed to produce interferon, and found that these mice received no benefit from DMXAA.

"H1N1 was a wake-up call that the flu remains a very serious disease, regardless of how "common" we may think i
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Chemical compounds in trees can fight deadly staph infections in humans
2. Good diets fight bad Alzheimers genes
3. Media advisory -- Partnering to Fight TB: The Role of a TB Vaccine PDP
4. Roses get celery gene to help fight disease
5. NRL scientists elevate warfighter readiness against invisible threats
6. Research suggests HIV causes rapid aging in key infection-fighting cells
7. Fighting the fight for healthy teeth
8. Scripps Research team creates new synthetic compound with HIV-fighting promise
9. Miscanthus has a fighting chance against weeds
10. The amount of adipose tissue should be taken into account in the fight against obesity
11. Researchers discover how natural drug fights inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2015)... TAIPEI , Feb. 13, 2015 ... service company that aims to transform cancer genomic ... announced that the company has raised US$ 8 million ... Based in Taipei, Taiwan ... tests, ACTDrug™, ACTOnco™. With the aim to implement ...
(Date:2/9/2015)...  Lintec of America recently announced an exclusive license ... macrostructures, including sheets, yarns and ribbons, developed at the ... the vast industrial resources of the global Lintec Group, ... of America is forming the Nano-Science and Technology Center ... on scaling up the manufacturing and commercialization of nano ...
(Date:2/5/2015)... , Jan. 27, 2015   Marvin ... globally deployed, innovative test solutions for military, ... delivery of its TS-323 GENASYS Test ... Company (LMSSC). GENASYS is a high-performance PXI-based ... mission-critical applications that require performance functional testing. ...
Breaking Biology News(10 mins):ACT Genomics Raises $8 Million in its First Private Funding Round 2Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 2Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 3Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 4Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4
... University study shows that detergents used to clean up spills ... making it more harmful. "The detergents may be the ... the dispersed oil is diluted and degraded," says Biology professor ... bioavailability and toxicity of the fuel to rainbow trout by ...
... discovered a new approach to prevent bacterial infections from ... Microbiology , Dr Quinn Parks and colleagues describe how ... defence cells to prevent Pseudomonas aeruginosa bacteria ... avoid both the body,s immune mechanisms and antibiotics. ...
... The viscosity, or ,gloopiness, of different parts of cancer ... cancer drugs, according to new images that provide fundamental ... Nature Chemistry today (15 March). ... inside cancer cells whilst they are dying as a ...
Cached Biology News:A sticky business -- how cancer cells become more 'gloopy' as they die 2
(Date:2/26/2015)... Feb. 26, 2015 Ceres, Inc . ... in Oracle PartnerNetwork. In attaining Gold Level membership, Ceres ... establish Oracle-related knowledge in delivering Ceres, Persephone genome visualization ... customers. Originally developed for in-house use by ... in and out of massive amounts of genetic data, ...
(Date:2/26/2015)... SAN FRANCISCO, Calif. , Feb. 26, 2015 /PRNewswire/ ... the treatment of cancer, today announced that Sean ... a corporate overview at the upcoming Cowen and Company ... Boston . Dr. McCarthy,s presentation will take ... About CytomX Therapeutics CytomX Therapeutics develops ...
(Date:2/25/2015)... 25, 2015 truBrain , creator ... in this week,s Power Pitch segment of CNBC,s  ... the company,s traction and growth strategy, as well ... funding site CircleUp. The segment highlights ... validated by neurotechnology, while also discussing its decision ...
(Date:2/25/2015)... 25, 2015 AnthroTronix ( http://www.atinc.com ... to optimizing the interaction between people and technology, ... Award Finalist by the internationally renowned Edison Awards™ ... can provide health professionals data within minutes to ... injury and can provide baseline data on brain ...
Breaking Biology Technology:Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4CNBC's Power Lunch Features Neurotechnology Start-up truBrain 2AnthroTronix Named Edison Awards Finalist for Brain Health Assessment Tool 2AnthroTronix Named Edison Awards Finalist for Brain Health Assessment Tool 3
... HARBIN, China, Sept. 15, 2011 /PRNewswire-Asia/ -- China Botanic Pharmaceutical ... "Company"), a developer, manufacturer and distributor of botanical products, bio-pharmaceuticals ... results for the three months ended July 31, 2011. ... Highlights and Recent Events ...
... New York Stem Cell Summit is releasing effective today an ... the general public understand more accurately the role that autologous ... today. Approximately 1 million patients have been treated ... United States. Harvesting stem cells from adult ...
... 2011 Aperion Biologics, Inc. announced that it has ... the Company,s clinical trial of its Z-Lig™ Anterior Cruciate ... injuries of the knee. The randomized multicenter study commenced ... to provide safety and performance data in the reconstruction ...
Cached Biology Technology:China Botanic Pharmaceutical Reports Third-Quarter Fiscal Year 2011 Results 2China Botanic Pharmaceutical Reports Third-Quarter Fiscal Year 2011 Results 3China Botanic Pharmaceutical Reports Third-Quarter Fiscal Year 2011 Results 4China Botanic Pharmaceutical Reports Third-Quarter Fiscal Year 2011 Results 5China Botanic Pharmaceutical Reports Third-Quarter Fiscal Year 2011 Results 6China Botanic Pharmaceutical Reports Third-Quarter Fiscal Year 2011 Results 7China Botanic Pharmaceutical Reports Third-Quarter Fiscal Year 2011 Results 8New York Stem Cell Summit Issues Adult Stem Cell Fact Sheet 2Aperion Biologics Reaches Midpoint of Enrollment in Z-Lig™ Anterior Cruciate Ligament Reconstruction Medical Device Performance Trial 2
ANTI PIG LDH H4...
RAT ANTI MOUSE F4/80 ANTIGEN:BIOTIN Immunogen: Thioglycollate stimulated peritoneal macrophages from C57/BL mice...
... boxes are ideal for use in refrigerators, freezers, or ... Four vibrant colors allow for color coding to project, ... nitrogen drainage or promote cool air circulation. Supplied with ... 100 tubes. Box dimensions: 13 x 13 ...
Sterile glass 5 mm beads that make spreading bacterial and yeast cultures easy. Can be washed, autoclaved and reused....
Biology Products: