Navigation Links
Drug aimed at 2 bioterror agents blocks live viral infection, Weill Cornell team reports
Date:12/19/2007

their particular shapes prevent 'doors' in the viral 'fusion protein' from closing as they should. The parainfluenza peptide's shape simply makes it a better door jamb," Dr. Porotto said.

Much of this research is modeled on insights gained from two decades of investigation into another lethal virus, HIV. In fact, T-20, or Fuzeon -- one of the earliest effective HIV-suppressing drugs -- acts on a similar principle to block that virus' entry into cells.

The next step, according to the researchers, is to use what they've learned to design even more effective peptides that should work even better.

"However, one issue with peptides is that you have to be concerned about how long they are going to last in the bloodstream," Dr. Moscona says. "So, we are also developing methods of sustained-release -- for example, encasing the peptide in a polymer pellet that would be injected under the skin. The pellet would then release the drug slowly over the course of a week. That could form a viable method suitable for stockpiling," she says.


'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Using evolution, UW team creates a template for many new therapeutic agents
2. Primate behavior explained by computer agents
3. Building blocks of life
4. Natural product discovery by Cleveland medical researchers blocks tissue destruction
5. Scripps research team blocks bacterial communication system to prevent deadly staph infections
6. Building blocks of life formed on Mars
7. Clearance of hepatitis C viral infection after liver transplantation
8. Feline virus, antiviral drug studied to understand drug resistance
9. Cornell will host the Northeast Biofuel Summit, Nov. 11-13
10. First symposium of UN University-Cornell Africa Series to be held at UN
11. Wiggle room: Cornell researcher borrows idea from sperm to provide energy for nanoscale robots
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... puts out a welcome mat to bacteria seeking to invade, ... study published this week in the Proceedings of the ... battle between microbe and host that researchers can exploit to ... oft-studied plant Arabidopsis puts out a molecular signal ... a hostile army were unknowingly passing by a castle, and ...
(Date:4/23/2014)... chronic inflammatory disorders among people of lower socioeconomic status ... to the microbes that thrive in rural environments, according ... in the journal Clinical & Experimental Immunology , ... less access to green spaces may be more apt ... system dysfunction. , When our immune systems are working ...
(Date:4/23/2014)... new study from the Indiana University School of Public ... and heart disease by finding a strong association between ... coronary heart disease. , The study found that heme ... by 57 percent, while no association was found between ... sources, and coronary heart disease. , The study was ...
Breaking Biology News(10 mins):How a plant beckons the bacteria that will do it harm 2How a plant beckons the bacteria that will do it harm 3Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3Study: Iron consumption can increase risk for heart disease 2
... Researchers have identified genetic markers that may influence whether ... according to a national longitudinal study of thousands of young ... Developmental Psychology , a publication of the American Psychological Association. ... related in any way to academic achievement is a big ...
... laparoscopic surgery "minimally invasive" instruments enter the patient through ... work on different tasks, surgeons all see the same view. ... suited to the specific task? In a new paper, pediatric ... Brown University and Hasbro Children,s Hospital report that in a ...
... Cancer Center have uncovered a single molecule they say ... used to treat or prevent breast cancer in high-risk ... Cancer Research , the scientists say glucose-regulated protein 78 ... the agents tamoxifen and fulvestrant, turns off apoptosis, a ...
Cached Biology News:Genes may play role in educational achievement, study finds 2Individual perspectives improve laparoscopy 2Individual perspectives improve laparoscopy 3Single protein promotes resistance to widely used anti-estrogen drugs 2Single protein promotes resistance to widely used anti-estrogen drugs 3
(Date:1/15/2014)... Niagara Thermal Products is proud to announce that ... ("B3") as the critical thermal component supplier in support ... Corps of Engineers.  B3 has developed the only comprehensive ... destroys VOCs and other chemical pollutants, allergens and organic ...
(Date:1/15/2014)... This webinar will focus on EMA ... assessment in biosimilars. , Regulatory frameworks are evolving many ... however the complex nature of biopharmaceuticals makes the demonstration ... extremely challenging. Based on the specific aspects of biosimilar ...
(Date:1/15/2014)... 15, 2014 DTS Language Services, Inc ... Web Portal for Life Science organizations who need document translations. ... subject matter of their documents in advance with a selection ... time-to-delivery of translations, often a critical factor in clinical and ...
(Date:1/14/2014)... 2014 Date: Friday, April 11, 2014 , ... Club, 1360 Almshouse Road, Warrington, Pa. , Details: ... dedicated to finding a cure for hepatitis B and improving ... its annual Crystal Ball on Friday, April 11 at Warrington ...
Breaking Biology Technology:Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2DTS Improves Efficiency for Life Science Document Translations 2Hepatitis B Foundation to Host Annual Crystal Ball Gala 2
... 17, 2012 The " Anesthesia Drugs ... analyzes and studies the U.S. market for intravenous anesthesia drugs with ... buyers, export & import system for controlled substances in U.S. and U.S. ... in-depth TOC of   " Anesthesia Drugs ...
... clinical trial, a paralyzed woman was able to reach for and ... time in nearly 15 years by using her thoughts to ... the National Institutes of Health, is evaluating the safety and feasibility ... This is a type of brain-computer interface (BCI) intended to put ...
... 2012  Questcor Pharmaceuticals, Inc. (NASDAQ: QCOR ) ... the Company,s common share repurchase program authorization by an ... of 2008, the Company has returned $236 million to ... and preferred shares, representing approximately 27% of its shares ...
Cached Biology Technology:Anesthesia Drugs Market in U.S. worth $7 Billion by 2015: MarketsandMarkets 2Anesthesia Drugs Market in U.S. worth $7 Billion by 2015: MarketsandMarkets 3Paralyzed individuals use thought-controlled robotic arm to reach and grasp 2Paralyzed individuals use thought-controlled robotic arm to reach and grasp 3Paralyzed individuals use thought-controlled robotic arm to reach and grasp 4Paralyzed individuals use thought-controlled robotic arm to reach and grasp 5Questcor Pharmaceuticals Expands Repurchase Program 2Questcor Pharmaceuticals Expands Repurchase Program 3Questcor Pharmaceuticals Expands Repurchase Program 4Questcor Pharmaceuticals Expands Repurchase Program 5
Goat anti-VAV2 Class: Antibody Product Group: Miscellaneous Antibody...
Rabbit polyclonal to M13 Bacteriophage Coat Proteins ( Abpromise for all tested applications)....
E2F-5...
Rabbit polyclonal to Flagellin ( Abpromise for all tested applications). Antigen: Synthetic peptide from the flagellin C terminal domain of Burkholderia pseudomallei....
Biology Products: