Navigation Links
Double trouble: Bacterial super-infection after the flu
Date:1/22/2010

San Diego, CA Current research suggests that the flu may predispose to secondary bacterial infections, which account for a significant proportion of mortality during flu pandemics. The related report by Lee et al, "A mouse model of lethal synergism between influenza virus and Haemophilus influenzae," appears in the February 2010 issue of The American Journal of Pathology.

Influenza affects between three and five million people annually, causing up to 500,000 deaths worldwide. While most people will recover in one to two weeks, others will develop life-threatening conditions such as pneumonia or bronchitis. High-risk groups for seasonal influenza include the very young and old, people with compromised immune systems, and pregnant women. However, during influenza pandemics, mortality may be significant in previously healthy young adults.

A common complication of flu infection is a secondary "super-infection" by bacteria, which greatly increases the morbidity and mortality of the disease. The most common bacterial agents found following flu pandemics have been Streptococcus pneumoniae, Haemophilus influenzae, Group A Streptococcus, and Staphylococcus aureus. Furthermore, reports of infection with antibiotic-resistant strains have been increasing in recent years.

To explore the mechanisms governing the increased pathogenesis of flu upon super-infection, a group led by Dr. Sally R. Sarawar of the Torrey Pines Institute for Molecular Studies, San Diego, California confirmed that otherwise nonlethal influenza and H. influenzae infections cause high mortality rates in mice when flu infection precedes H. influenzae infection. Their data confirm a restricted time period for this heightened susceptibility and highlight that excessive bacterial, and not viral, growth is associated with increased lethality. The fact that this increased mortality was observed in both immunocompromised a
'/>"/>

Contact: Angela Colmone, Ph.D.
acolmone@asip.org
301-634-7953
American Journal of Pathology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Poor in rural Oregon face double binds when getting food
2. GATC Biotech AG is investing more than 5 million euros in its Constance site to double the companys floor space
3. Tumor suppressor pulls double shift as reprogramming watchdog
4. Surviving mass extinction by leading a double life
5. Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation
6. Stress puts double whammy on reproductive system, fertility
7. Aussie and Kiwi researchers make double MS genetic discovery
8. Double trouble for water life
9. New book, Untangling the Double Helix, explores enzymes responsible for maintaining genome integrity
10. Cells with double vision
11. Tree deaths have doubled across the western US
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)...  Since its launch in December 2014, the 1U™ ... of trying to remember their usernames and passwords through replacing ... smartphones. To assist people who have struggled to remember usernames ... 1U and focuses on redefining identity, announced today that it ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... "Micro Market Monitor: North America Perimeter Security Systems Market" ... The North American perimeter security market is ... to 2019. Although the U.S. market holds a larger share ...
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB SM ... (GCP) audit to confirm its adherence to current U.S. ... HITLAB to conduct regulated smart device and smart phone ... and research quality. "HITLAB is determined to ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... study of consumers, reactions to genetic testing found that ... those individuals had few negative reactions to the news. ... people to take positive steps, including follow-up visits with ... also be at risk. The study, titled "Dealing ...
... The research has determined two molecular ... face , The discovery may lead to future understanding of ... news release is below. LOS ANGELES Using ... discovered clues to the development of the head at the ...
... study of the Umpqua River basin in the Oregon ... of valleys and provides potentially useful details for river ... ( Oncorhynchus kisutch ). Coho salmon thrive in ... the main river. These valleys formed after large landslides ...
Cached Biology News:Consumers have few negative reactions to the results of genetic testing for cancer mutations 2USC researchers find possible genetic clues to organ development, birth defects 2Large, ancient landslides delivered preferred upstream habitats for coho salmon 2Large, ancient landslides delivered preferred upstream habitats for coho salmon 3Large, ancient landslides delivered preferred upstream habitats for coho salmon 4
(Date:1/23/2015)... (PRWEB) January 23, 2015 Portal Solutions ... digital workplaces on Microsoft Office 365 and SharePoint platforms ... 50 Award program for being one of the region’s fastest-growing ... and employee growth. , “To be recognized a second ...
(Date:1/22/2015)... today announces the firm brokered a long-term lease totaling 202,492 ... company, at Two Ledgemont Center in Lexington, Massachusetts ... and Brian Cohen , senior vice president, represented Shire ... Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... CAMBRIDGE, Mass (PRWEB) January 21, 2015 Cambridge ... Semantic Web technology, today announced that 2014 was a record-breaking ... expanding the capabilities of the Anzo Smart Data Platform and ... discover and utilize insights from diverse data which led to ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Crystal Diagnostics (CDx) ... that it has received AOAC-PTM Certifications for the six non-O157 ... and O145; collectively referred to as STEC or the “Big-6”) ... colony forming unit (cfu) per 325 g of raw ground ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Cambridge Semantics Announces Record Results for 2014 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2
... /PRNewswire-FirstCall/ - MIGENIX Inc.,(TSX: MGI; OTC: MGIFF), ... reports financial results for the three months ... its programs., UPDATE ON DRUG DEVELOPMENT ... cationic peptide;,prevention of catheter-related infections): A pivotal ...
... new validation studies,were published during 2007 on the ... number of studies published to 65., "This ... interest from US and,European institutes" said Gary Zamler, ... academic medical institutions and teaching hospitals,have completed studies ...
... (Nasdaq: NBIX ) announced today that the Company ... (FDA) indicating,that the New Drug Application (NDA) for indiplon ... insomnia is approvable pending additional clinical and,preclinical data., ... letter from the FDA,stating that indiplon 5 mg and ...
Cached Biology Technology:MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 2MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 3MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 4MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 5MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 6MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 7MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 8MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 9MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 10MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 11MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 12MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 13MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 14MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 15MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 16MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 17MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 182007 a "Record Year" for Successful Validation Studies of Simbionix Simulators 2Neurocrine Receives Approvable Letter for Indiplon Capsules with Additional Safety and Efficacy Data Required by FDA 2Neurocrine Receives Approvable Letter for Indiplon Capsules with Additional Safety and Efficacy Data Required by FDA 3
... requirements, IonQuest will provide great value ... conductivity detector has very high sensitivities ... addition to the standard conductivity detector, the ... such as electrochemical, refractive index, UV/Visible, WaveQuest ...
... Hamamatsu C9136 FLIM system combines the space and ... the resolution of the optical microscope to open ... short, pulsed light source for excitation, the decay ... the lifetime of the decay measured. Subtle ...
... SDS and Non-ionic Detergent Removal ... , Very selective, virtually no cross-reactivity with ... and discard pellet , Economical new ... , Detergents can often interfere with protein ...
... FLA-5000 imaging system allows scanning ... as large as 40 x ... as 25 microns. This system ... electrophoresis in the proteomics field ...
Biology Products: