Navigation Links
Don't go changing: New chemical keeps stem cells young
Date:2/3/2009

Scientists at the Universities of Bath and Leeds have discovered a chemical that stops stem cells from turning into other cell types, allowing researchers to use these cells to develop new medical treatments more easily.

Stem cells have the ability to develop into many other cell types in the body, and scientists believe they have huge potential to treat diseases or injuries that don't currently have a cure.

Professor Melanie Welham's team at the University of Bath's Department of Pharmacy & Pharmacology, collaborating with Professor Adam Nelson at the University of Leeds, have discovered a chemical that can be added to embryonic stem cells grown in the lab, allowing them to multiply without changing into other cell types.

This breakthrough will help scientists produce large stocks of cells that are needed for developing new medical therapies.

Professor Welham, who is co-director of the University of Bath's Centre for Regenerative Medicine, explained: "Stem cells have great potential for treating spinal injuries and diseases like type I diabetes because they can change into a range of specialised cell types including nerve or pancreatic cells, which could be used to repair damaged tissues.

"Unfortunately, when you grow stem cells in the lab, they can spontaneously develop into specialised cells, making it difficult to grow large enough stocks to use for medical research.

"We've identified a chemical that will put this process on hold for several weeks so that we can grow large numbers of them in their unspecialised state. This is reversible, so when you take it away from the cells, they still have the ability to change into specialised cells."

Professor Adam Nelson's team, at the Astbury Centre for Structural Molecular Biology, made more than 50 chemical compounds that were tested for activity in the stem cells.The researchers found that the chemicals worked by blocking an enzyme, called GSK3, that
'/>"/>

Contact: Vicky Just
v.j.just@bath.ac.uk
44-012-253-86883
University of Bath
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
2. American Chemical Societys Weekly PressPac -- Aug. 8, 2007
3. Thermochemical process converts poultry litter into bio-oil
4. New chemically-sensitive MRI scan may bypass some invasive diagnostic tests in next decade
5. Natural chemical found in broccoli helps combat skin blistering disease
6. American Chemical Societys Weekly PressPac -- Aug. 15, 2007
7. American Chemical Societys Weekly Press Pac
8. Amber specimen captures ancient chemical battle
9. American Chemical Societys Weekly Presspac -- Aug. 29, 2007
10. American Chemical Society calls green chemistry bill a smart step
11. Institution of Chemical Engineers chooses Elsevier as publishing partner
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Don't go changing: New chemical keeps stem cells young
(Date:8/28/2014)... your neighbors than traditional cigarettes, but still release ... study from USC. , Scientists studying secondhand smoke ... exposure to harmful particles, with close-to-zero exposure to ... harmful metals in second-hand e-cigarette smoke were found ... contains high levels of polycyclic aromatic hydrocarbons ...
(Date:8/28/2014)... Bethesda, MD FASEB MARC (Maximizing Access to ... recipients for the Genetics Society of America,s 27th ... October 3, 2014 in Pacific Grove, California. ... entry of students, post doctorates and scientists from ... science community and to encourage the participation of ...
(Date:8/28/2014)... for delivering compounds that could positively impact ... may be possible, thanks to researchers in ... semi-soft vaginal suppository made from the seaweed-derived ... antiviral drug Tenofovir provides a woman-initiated, drug-delivery ... of sexually transmitted infections during unprotected heterosexual ...
Breaking Biology News(10 mins):Second-hand e-cig smoke compared to regular cigarette smoke 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 3
... at Vanderbilt University have "engineered" a mouse that can ... normal mouse by increasing its supply of acetylcholine, the ... month in the journal Neuroscience, could lead to new ... occurs when cholinergic nerve signals fail to reach the ...
... Plastics-based materials have been in use for decades. ... their quest for new developments: Substantial influences of ... cannot be observed directly. The synthetic polymer molecules ... mechanical experiments. A team of physicists led by ...
... scientists and physicians at the Medical College of Wisconsin and ... treat an unknown disease. For the one of the ... Medical College of Wisconsin and Children,s Hospital of Wisconsin sequenced ... previously-unknown mutation. The team was able not only to ...
Cached Biology News:Boosting supply of key brain chemical reduces fatigue in mice 2Muscle filaments make mechanical strain visible 2Scientists and physicians use genetic sequencing to identify and treat unknown disease 2
(Date:8/28/2014)... Woodstock, Vt. (PRWEB) August 28, 2014 ... microbiology testing around the world is available from ... industrial diagnostics companies. “ Industrial Microbiology Market Review, ... the Industrial Market ” (IMMR—4) tracks and compares ... in in North America, Europe and Asia, and ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Whitehouse Laboratories ... long term partnership with PTI Inspection Systems ... with state of the art leak testing method development ... art instruments currently available. As part of this agreement, ... High Voltage Leak Detection Instrument developed and manufactured ...
(Date:8/27/2014)... Livermore, California (PRWEB) August 27, 2014 ... (LLNL), through Lawrence Livermore National Security ... million to develop and deliver a state-of-the-art laser ... Beamlines facility (ELI Beamlines), under construction in the ... design performance, the laser system, called the " ...
(Date:8/27/2014)... TX (PRWEB) August 27, 2014 The ... and in-depth study on the current state of the ... report provides a basic overview of the industry, including ... and Chinese domestic market analysis are provided with a ... the market. A comparison between the international and Chinese ...
Breaking Biology Technology:2 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3LLNL Synchs up with ELI Beamlines on Timing System 2LLNL Synchs up with ELI Beamlines on Timing System 3Trifluoroacetic Acid Industry (Asia, Europe, North America, ROW) Analysis Report Now Available at ReportsnReports.com 2
... Colo., March 23 N30 Pharma (N30) today ... the Board of Directors of the Company.Dr. Loscalzo ... and Practice of Medicine at Harvard , ... Circulation, and has recently joined the senior editorial ...
... ("BVF") today announced that PROXY Governance, widely recognized as a ... for all BVF Proposals on the GOLD proxy card for ... ) to be held on March 27, 2009.In its report ... (BVF) must clear a high bar to justify a change ...
... March 23 PAREXEL International Corporation (Nasdaq: ... provider, today announced that the Company has received ... from BioSingapore, an industry association for life sciences ... Singapore. The award was presented to PAREXEL at ...
Cached Biology Technology:Leading Advisory Firm, PROXY Governance, Recommends Avigen Shareholders Vote on GOLD Card to Remove Incumbent Directors and Elect BVF's Stockholder-Oriented Nominees 2PAREXEL Receives BioSingapore Award for Best Performing CRO 2PAREXEL Receives BioSingapore Award for Best Performing CRO 3PAREXEL Receives BioSingapore Award for Best Performing CRO 4
Phospho-CD18 (Ser756/Thr758/759) Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Goat polyclonal to SART1 ( Abpromise for all tested applications). Antigen: Synthetic peptide: GSSKKHRGEKEAA, corresponding to N terminal amino acids 2-14 of Human SART1. Entrez Gene ID: 909...
Phospho-Cyclin D1 (Thr286) Antibody...
STX18 Immunogen: STX18 (NP_058626, 101 a.a. ~ 200 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Biology Products: