Navigation Links
Does your job increase your breast cancer risk?

Is there a link between the risk of breast cancer and the working environment? A study published in BioMed Central's open access journal Environmental Health provides further evidence on this previously neglected research topic, confirming that certain occupations do pose a higher risk of breast cancer than others, particularly those that expose the worker to potential carcinogens and endocrine disrupters.

Breast cancer is the most frequent cancer diagnosis among women in industrialized countries, and North American rates are among the highest in the world. Endocrine-disrupting chemicals and carcinogens, some of which may not have yet been classified as such, are present in many working environments and could increase breast cancer risk. In their study, James T Brophy and his colleagues set out to characterize the possible links between breast cancer and occupation, particularly in farming and manufacturing.

The population-based case-control study was conducted in Southern Ontario, Canada, and included 1006 breast cancer cases (referred by the Windsor Regional Cancer Centre) with 1147 randomly selected and matched community controls. Using interviews and surveys, the team collected data on participants' occupational and reproductive histories. All jobs were coded for their likelihood of exposure to carcinogens and endocrine disruptors, and patients' tumor pathology regarding endocrine receptor status was assessed.

The authors found in this group of participants that, across all sectors, women in jobs with potentially high exposures to carcinogens and endocrine disrupters had an elevated breast cancer risk. Sectors with increased risk included agriculture, bar/gambling, automotive plastics manufacturing, food canning and metal-working. Importantly, premenopausal breast cancer risk was highest in the automotive plastics and food canning industries.

The findings also suggested that women with lower socioeconomic status had an elevated risk of breast cancer, which may result from higher exposures to endocrine-disrupting chemicals in the lower-income manufacturing and agricultural industries of the study area.

The results lend weight to hypotheses linking breast cancer risk and exposures likely to include carcinogens and endocrine disrupters. Lead author Brophy said, "Our results highlight the importance of occupational studies in identifying and quantifying environmental risk factors and illustrates the value of taking detailed occupational histories of cancer patients. Mounting evidence suggests that we need to re-evaluate occupational exposure limits in regulatory protection."


Contact: Hilary Glover
BioMed Central

Related biology news :

1. Increase in Arctic shipping poses risk to marine mammals
2. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
3. Fertilizer use responsible for increase in nitrous oxide in atmosphere
4. NIST/UMass study finds evidence nanoparticles may increase plant DNA damage
5. Study finds soda consumption increases overall stroke risk
6. Scientists have discovered genes that increase the risk of osteoporosis and fractures
7. Family history of liver cancer increases risk of developing the disease
8. Research shows how PCBs promote dendrite growth, may increase autism risk
9. Increased fructose consumption may deplete cellular energy in patients with obesity and diabetes
10. NIH-led study finds genetic test results do not trigger increased use of health services
11. Flapping protective wings increase lift
Post Your Comments:
(Date:6/3/2016)... June 3, 2016 ... Nepal hat ein ... hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und ... der Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche ... im Januar teilgenommen, aber Decatur wurde als ...
(Date:5/24/2016)... Calif. , May 24, 2016 Ampronix facilitates superior patient care by ... LMD3251MT  3D medical LCD display is the latest premium product recently added to the ... ... ... Sony 3d Imaging- LCD Medical Display- Ampronix News ...
(Date:5/3/2016)... VILNIUS, Lithuania , May 3, 2016 /PRNewswire/ ... today released the MegaMatcher Automated Biometric Identification ... deployment of large-scale multi-biometric projects. MegaMatcher ABIS can ... and accuracy using any combination of fingerprint, face ... of MegaMatcher SDK and MegaMatcher ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... Charm ... Mold) microbial test has received AOAC Research Institute approval 061601. , “This is ... last year,” stated Bob Salter, Vice President of Regulatory and Industrial Affairs. “The ...
(Date:6/23/2016)... NEW YORK , June, 23, 2016  The ... students to envision new ways to harness living systems ... of Modern Art (MoMA) in New York ... more than 130 participating students, showcased projects at MoMA,s ... included Paola Antonelli , MoMA,s senior curator of ...
(Date:6/23/2016)... ... 23, 2016 , ... Supplyframe, the Industry Network for electronics ... Lab . Located in Pasadena, Calif., the Design Lab’s mission is to bring ... designed, built and brought to market. , The Design Lab is Supplyframe’s physical ...
(Date:6/23/2016)... ... June 23, 2016 , ... In a new case report ... detail how a patient who developed lymphedema after being treated for breast cancer benefitted ... change the paradigm for dealing with this debilitating, frequent side effect of cancer treatment. ...
Breaking Biology Technology: