Navigation Links
Does your job increase your breast cancer risk?
Date:11/19/2012

Is there a link between the risk of breast cancer and the working environment? A study published in BioMed Central's open access journal Environmental Health provides further evidence on this previously neglected research topic, confirming that certain occupations do pose a higher risk of breast cancer than others, particularly those that expose the worker to potential carcinogens and endocrine disrupters.

Breast cancer is the most frequent cancer diagnosis among women in industrialized countries, and North American rates are among the highest in the world. Endocrine-disrupting chemicals and carcinogens, some of which may not have yet been classified as such, are present in many working environments and could increase breast cancer risk. In their study, James T Brophy and his colleagues set out to characterize the possible links between breast cancer and occupation, particularly in farming and manufacturing.

The population-based case-control study was conducted in Southern Ontario, Canada, and included 1006 breast cancer cases (referred by the Windsor Regional Cancer Centre) with 1147 randomly selected and matched community controls. Using interviews and surveys, the team collected data on participants' occupational and reproductive histories. All jobs were coded for their likelihood of exposure to carcinogens and endocrine disruptors, and patients' tumor pathology regarding endocrine receptor status was assessed.

The authors found in this group of participants that, across all sectors, women in jobs with potentially high exposures to carcinogens and endocrine disrupters had an elevated breast cancer risk. Sectors with increased risk included agriculture, bar/gambling, automotive plastics manufacturing, food canning and metal-working. Importantly, premenopausal breast cancer risk was highest in the automotive plastics and food canning industries.

The findings also suggested that women with lower socioeconomic status had an elevated risk of breast cancer, which may result from higher exposures to endocrine-disrupting chemicals in the lower-income manufacturing and agricultural industries of the study area.

The results lend weight to hypotheses linking breast cancer risk and exposures likely to include carcinogens and endocrine disrupters. Lead author Brophy said, "Our results highlight the importance of occupational studies in identifying and quantifying environmental risk factors and illustrates the value of taking detailed occupational histories of cancer patients. Mounting evidence suggests that we need to re-evaluate occupational exposure limits in regulatory protection."


'/>"/>

Contact: Hilary Glover
hilary.glover@biomedcentral.com
44-020-319-22370
BioMed Central
Source:Eurekalert

Related biology news :

1. Increase in Arctic shipping poses risk to marine mammals
2. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
3. Fertilizer use responsible for increase in nitrous oxide in atmosphere
4. NIST/UMass study finds evidence nanoparticles may increase plant DNA damage
5. Study finds soda consumption increases overall stroke risk
6. Scientists have discovered genes that increase the risk of osteoporosis and fractures
7. Family history of liver cancer increases risk of developing the disease
8. Research shows how PCBs promote dendrite growth, may increase autism risk
9. Increased fructose consumption may deplete cellular energy in patients with obesity and diabetes
10. NIH-led study finds genetic test results do not trigger increased use of health services
11. Flapping protective wings increase lift
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2016)... BARCELONA , España y TORONTO , 19 ... fusión con Northern Biologics Inc. que permitirá el desarrollo acelerado de ... ensayos clínicos en varios tipos de tumor en 2017, con múltiples ... ... de su clase con objetivo en el factor inhibidor de leucemia ...
(Date:12/15/2016)... , December 15, 2016 Arvato ... an agreement with NuData Security, an award-winning international ... will enable clients to focus on good customer experience, balancing ... regulation. ... In order to provide a one-stop fraud prevention suite, Arvato ...
(Date:12/15/2016)... , Dec. 15, 2016  There is much ... doors or starting the engine. Continental will demonstrate the ... Las Vegas . Through the combination of ... and Entry) and biometric elements, the international technology company ... vehicle personalization and authentication. "The integration of ...
Breaking Biology News(10 mins):
(Date:1/12/2017)... Frederick, MD (PRWEB) , ... ... ... to the market’s rapid adoption of Limfinity® Cloud, RURO has enhanced the ... for cross-continent user groups, federated login, rapid data searching, and more. In ...
(Date:1/11/2017)... 2017  Brian Mehling, M.D., world-renowned stem cell researcher, ... International (BHI), will be attending the 47th Annual World ... from January 17-20, 2017. This will be Dr. Mehling,s ... theme of this year,s forum is Responsive and Responsible ... address strategies for fostering greater social inclusion and human ...
(Date:1/11/2017)... , ... January 11, 2017 , ... ... make all the difference when navigating the challenges young businesses face. With the ... the extensive expertise and experience of Geoff DiMasi, Founder and Principal of interactive ...
(Date:1/11/2017)... , Jan. 11, 2017 AnaptysBio, ... product candidates focused on unmet medical needs in ... Piscitelli as chief financial officer.  Mr. Piscitelli ... strategy, as well as overseeing the company,s accounting ... are pleased to welcome Dominic to the senior ...
Breaking Biology Technology: