Navigation Links
Does the existing standard of care supply energy sources to brain tumor cells?
Date:7/14/2010

iated macrophages and monocytes (TAMs) that flood the brain in an effort to battle tumor cells can indirectly support tumor growth through the release of agents that lead to inflammation and the growth of blood vessels.

"What develops then is an escalating situation of biological chaos, where the intrinsic properties of TAMs to heal wounds increase the capacity of brain tumor cells to proliferate, invade, and self-renew," writes Seyfried and his co-authors, researchers Laura M. Shelton and Purna Mukherjee. "High glucose concentrations together with unrestricted glutamine availability will provide the energy necessary to drive this escalating situation."

Seyfried says this "perfect storm" of side-effects from the standard of care for glioblastoma should invite a broader discussion among researchers for potential alternative therapies. Through his past research, Seyfried has detailed the benefits of non-toxic metabolic therapies involving ketogenic diets that effectively restrict glucose-based fuels to brain tumors. By regulating glucose availability while simultaneously elevating fat-derived ketone bodies, which brain tumors cannot actively use for growth or survival, the ketogenic diet has been shown to control epileptic seizures, but there have been no human trials to test its therapeutic efficacy against brain cancer.


'/>"/>

Contact: Ed Hayward
ed.hayward@bc.edu
617-552-4826
Boston College
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study points to new uses, unexpected side effects of already existing drugs
2. Stress signals link pre-existing sickness with susceptibility to bacterial infection
3. Complications early in pregnancy or in previous pregnancies adversely affect existing or subsequent pregnancies
4. Nature cover study provides new standards for reliable fisheries
5. Gold Standard/Elsevier offers timely, reliable drug pricing data, including average wholesale price
6. Meet Phannie, NISTs standard phantom for calibrating MRI machines
7. Aware, Inc. Joins HIMSS10 Interoperability Showcase to Demonstrate Standards-Based Medical Image Sharing
8. Researchers develop standard of care for breast cancer survivors with lymphedema
9. Stent grafts top gold standard balloon angioplasty for dialysis patients
10. Quality and safety of infant formulas, functional foods enhanced by new standards
11. U. of I. business instructional facility achieves top green standard
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/17/2015)... 17, 2015  MecklerMedia Corporation (OTCQX: MECK) announced ... service robots ever held in New ... May 11-13, 2015 at the Javits Convention Center. ... event include: Acorn Product Development; Axis NJ; c-Link ... Robotics; Littler; NewBotic Corporation; Neya Systems LLC; Reliabotics; ...
(Date:3/12/2015)... , March 12, 2015 WHEN:Tuesday, March ... Registration here: http://bit.ly/1G7Os0L . SPEAKERS: , Frost ... SeshagiriPhoto - http://photos.prnewswire.com/prnh/20150311/181111 Biometric ... to compete in several different markets and industries. ... currently witnessing an uptrend. Join ...
(Date:3/10/2015)... PROVO, Utah , March 10, 2015   ... genome interpretation, has been selected by next-generation sequencing company ... provider of whole exome and targeted gene panel interpretation. ... sequencing provider, has adopted the most current technologies to ... of genetic research. The company offers two types of ...
Breaking Biology News(10 mins):MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 2PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 3
... A nutritionist whose research was instrumental in adding fruits and ... subsidy will receive the March of Dimes Agnes Higgins Award ... Gail Harrison, Ph.D., MNS, , a professor in ... California, Los Angeles School of Public Health, will receive the ...
... month of the publication of On the Origin of ... publishing open access two peer-reviewed articles about Charles Darwin ... articles are by Kevin Padian of the University of ... University. Padian,s article, "Ten Myths About Charles Darwin," appeared ...
... at Yale University have developed synthetic molecules capable of ... cells, as well as to prostate cancer cells. Their ... American Chemical Society , could lead to novel therapeutic ... called "antibody-recruiting molecule targeting HIV" (ARM-H) and "antibody-recruiting molecule ...
Cached Biology News:March of Dimes honors Dr. Gail Harrison for outstanding work in maternal-fetal nutrition 2New synthetic molecules trigger immune response to HIV and prostate cancer 2
(Date:3/26/2015)... 26, 2015 ReliantHeart, Inc., an innovative ... a supplier of precision transit-time flow measurement solutions, are ... improve the efficiency of the HeartAssist5® Left ... to experience greater mobility and peace of mind. ... flow board, will draw 1/6th of the power required ...
(Date:3/25/2015)... pharmaceutical market is one of the most attractive in ... size, plus a growing economy and increasing government investment ... International. The Russian market is set to grow at ... growth estimates around 10-15% annually reaching an approximate market ... Green Cross Green Cross provides total healthcare ...
(Date:3/25/2015)... 25, 2015 The surging prevalence ... have fuelled social media growth, with over 50% ... in social networking. Insurance companies are making use ... clients and promote a diversity of their services ... increasingly exploiting social networking services as part of ...
(Date:3/25/2015)... SHANGHAI , CAMBRIDGE, Mass. and ... -- WuXi NextCODE, which provides comprehensive capabilities for using the ... deCODE genetics on their publication of the largest studies of ... published today online in Nature Genetics ... date of sequence variation, authored by a team of deCODE ...
Breaking Biology Technology:LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 2LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 3Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3Landmark deCODE Studies Demonstrate the Power of Truly Big Genomics for Improving Medicine Worldwide 2
... Wisconsin, there is a growing belief that whenever a state ... local ownership inevitably harms the state's economy. But the recent ... Illinois-based CDW Corp . has a real chance to ... to the deal. , ,The win-win view not only was ...
... Wis . - What a difference a quiet hurricane ... business executives. While slow, steady growth was anticipated, area ... according to the fourth annual Economic Survey of Dane ... the University of Wisconsin-Madison School of ...
... Wis. - Tushaus Computer Services , which ... Millennium Design, Inc., a provider of Apple products and ... PCs and Macs, but also intellectual property and technology ... organizations. Financial terms of the deal were not disclosed. ...
Cached Biology Technology:Anatomy of a deal: CDW and Berbee 2Anatomy of a deal: CDW and Berbee 3Anatomy of a deal: CDW and Berbee 4Economic survey reveals better 2006 results 2Economic survey reveals better 2006 results 3Economic survey reveals better 2006 results 4
... Weight Markers, 37 kBq, 1 uCi. Carbon-14 ... of the sample on Western blots.The Rainbow-labeled ... migration in the gel and on the ... without Rainbow-labeling is 0.37-3.7 MBq/mg (10-100 uCi/mg) ...
in vitro Translation, Accessory Products...
... The Zero Blunt TOPO ... Sequencing is designed for ... of blunt-end PCR products. ... 5-minute TOPO Cloning and ...
Request Info...
Biology Products: