Navigation Links
Does food act physiologically like a 'drug of choice' for some?
Date:7/19/2011

Variety is considered the "spice of life," but does today's unprecedented level of dietary variety help explain skyrocketing rates of obesity? Some researchers think it might.

According to ASN Spokesperson Shelley McGuire, PhD: "We've known for years that foods- even eating, itself- can trigger release of various brain chemicals, some of which are also involved in what happens with drug addiction and withdrawal. And, as can happen with substance abusers, tolerance or "habituation" can occur, meaning that repeated use (in this case, exposure to a food) is sometimes accompanied by a lack of response (in this case, disinterest in the food). The results of the study by Epstein and colleagues provides a very interesting new piece to the obesity puzzle by suggesting that meal monotony may actually lead to reduced calorie consumption. The trick will be balancing this concept with the importance of variety to good nutrition."

Studies have shown that many people become disinterested in a particular food when they are repeatedly exposed to it. This response, called habituation, can decrease caloric intake in the short-run. Conversely, when presented with a variety of foods, caloric intake can increase. The "food addiction hypothesis" purports that some people may overeat because they are insensitive to the normal habituation response and thus need even more exposure to a food to trigger a disinterest. However, there has been no rigorous research investigating whether healthy-weight and overweight individuals have different habituation responses, and little is known about what patterns of food exposure are most powerful in triggering habituation. To help close these research gaps, researchers studied long-term habituation in obese and nonobese women. Their results, and an accompanying editorial by Nicole Avena and Mark Gold, are published in the August 2011 issue of The American Journal of Clinical Nutrition.

Sixteen nonobese [BMI (in kg/m2) < 30] and 16 obese (BMI  30) women were randomly assigned to 1 of 2 groups: the "weekly group" participated in weekly experimental food exposure sessions for 5 wk, whereas the "daily group" were studied daily for 5 consecutive days. During each 28-min experimental session, subjects were asked to complete a variety of tasks after which they were "rewarded" by being given a 125-kcal portion of macaroni and cheese. Participants could work for as much food as they wanted. The researchers then evaluated total energy intake.

Whereas weekly food exposure increased total caloric intake by approximately 30 kcal/d, daily exposure decreased energy consumption by ~100 kcal/d. This supports long-term habituation in terms of caloric intake. Very few differences were found between how obese and nonobese individuals responded.

The authors concluded that reducing variety in food choices may represent an important strategy for those trying to lose weight. Moreover, having a person even remember that they have eaten a certain food recently may be effective in this regard. In their accompanying editorial, Avena and Gold compare physiologic components of the food addiction hypothesis to the body's addictive responses to drugs. They also ponder whether school-lunch planners and public health officials should note that diversity in the menu is not necessarily a virtue" but might instead "be associated with promoting excess food intake and increased body mass index." Provocative food for thought.


'/>"/>

Contact: Suzanne Price
sprice@nutrition.org
American Society for Nutrition
Source:Eurekalert

Related biology news :

1. Penn vet researchers show lymphoma drug shrinks dog tumors, could lead to human treatment
2. Research provides insight into new drug resistance in hospital microbes
3. Needle-in-a-haystack search for new drugs for brain diseases
4. GNS Healthcare Collaborates with NCI in New Approach to Lung Cancer; Supercomputer Analysis to Aid in Matching Targeted Drugs to Patients
5. Drug designer
6. Drug shield helps target antibiotic resistant bacteria
7. GEN point of view article questions reported costs of drug R&D
8. Unique gel capsule structure enables co-delivery of different types of drugs
9. UBC researchers invent new drug delivery device to treat diabetes-related vision loss
10. Will new drugs block hepatitis C virus in its tracks?
11. Premature aging caused by some HIV drugs, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/9/2016)... , UAE, May 9, 2016 ... it comes to expanding freedom for high net worth ... Even in today,s globally connected world, there is still ... system could ever duplicate sealing your deal with a ... second passports by taking advantage of citizenship via investment ...
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
(Date:4/13/2016)... , April 13, 2016  IMPOWER physicians supporting ... are setting a new clinical standard in telehealth thanks ... By leveraging the higi platform, IMPOWER patients can routinely ... pulse and body mass index, and, when they opt ... and convenient visit to a local retail location at ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita Politecnica delle Marche in ... peritoneal or pleural mesothelioma. Their findings are the subject of a new article on ... biomarkers are signposts in the blood, lung fluid or tissue of mesothelioma patients that ...
(Date:6/23/2016)...   Boston Biomedical , an industry leader ... target cancer stemness pathways, announced that its lead ... Designation from the U.S. Food and Drug Administration ... gastroesophageal junction (GEJ) cancer. Napabucasin is an orally ... stemness pathways by targeting STAT3, and is currently ...
(Date:6/23/2016)... HOUSTON , June 23, 2016 ... agreement with the Cy-Fair Sports Association to serve ... of the agreement, Houston Methodist Willowbrook will provide ... education and connectivity with association coaches, volunteers, athletes ... partner with the Cy-Fair Sports Association and to ...
(Date:6/23/2016)... 23, 2016  The Biodesign Challenge (BDC), a university ... to harness living systems and biotechnology, announced its winning ... New York City . ... showcased projects at MoMA,s Celeste Bartos Theater during the ... MoMA,s senior curator of architecture and design, and ...
Breaking Biology Technology: