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Disrupting a destructive duo: U of T Mississauga researchers inhibit cancer proteins
Date:8/20/2009

articular protein," says Gunning. "In some cases, they were more than twice as effective as the existing inhibitor."

When the team used more complex cancer cell models, they found the inhibitors survived the passage across the cell membrane and still targeted the Stat3 cancer proteins inside. Gunning and his colleagues are working to make the new inhibitors even more effective, as well as more metabolically stable, meaning that they can survive the chemical defense mechanisms within the cell.


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Contact: Nicolle Wahl
nicolle.wahl@utoronto.ca
905-569-4656
University of Toronto
Source:Eurekalert

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