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Disease genes that followed the Silk Road identified
Date:7/20/2010

es in this condition. The discovery could pave the way for new treatments for Behet's in the future.

Professor Ollier said: "Through establishing this major international collaboration between research groups from all over the world we have managed to identify and confirm some of the genes involved in this terrible condition.

"Hopefully, if we can collect larger numbers of patients, we will be able to go on to identify further genes which contribute smaller levels of risk. By identifying the genetic factors in Behcet's disease we will be in a position to establish the biological and biochemical pathways that cause the disease pathology. Only by doing this, will we be able to design the right drugs to correct these pathways and treat the patients.

"Our other long-term ambition is that we could use genetic testing to identify early cases in families with a history of the disease and predict which patients will have a more severe disease course and consequently require a more aggressive therapy."


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Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester
Source:Eurekalert

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