In 2010, after more than 10 years of basic research, Dr. Peter W. Schiller, a world-renowned peptide chemist and Director of the Chemical Biology and Peptide research unit at the Institut de recherches cliniques de Montral (IRCM), and his international collaborators were the listed inventors on two U.S. patents awarded to the institute and covering different uses of a unique class of peptide compounds initially synthesized in Dr. Schiller's laboratory at the IRCM.
A total of five U.S. patents have been awarded to the IRCM to date involving these new peptide compounds. Patent applications have also been filed in many other countries, including Canada, Europe, Japan, India, Australia, and China. The IRCM co-owns these patent families with Cornell University, located in New York state.
Stealth Peptides International Inc. (Stealth), a privately held biopharmaceutical company developing innovative therapies, has exclusively licensed commercial rights to the compounds and their various applications. Stealth plans to develop new treatments for metabolic, ophthalmologic, neurologic and cardio-renal diseases using these and other compounds.
Stealth's lead clinical candidate is BendaviaTM, a novel compound from this class of peptides that targets cell mitochondria to treat several acute and chronic diseases.
The first clinical program for Bendavia is for the treatment of ischemia reperfusion injury, a common complication of interventional procedures for acute myocardial infarction, a leading cause of death worldwide, as reported by the World Health Organization. An Investigational New Drug application for Bendavia was filed with the U.S. Food and Drug Administration and U.S. Phase I clinical trials began in May 2010. The initial U.S. Phase I clinical trial was designed to evaluate the clinical safety, tolerability and pharmacokinetics of Bendavia in healthy volunteers. In September 2010, Stealth's U.S. affiliate announced the com
'/>"/>
| Contact: Julie Langelier julie.langelier@ircm.qc.ca 514-987-5555 Institut de recherches cliniques de Montreal Source:Eurekalert |
Related biology news :
1. Chemical equator discovery will aid pollution mapping
2. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
3. Groundbreaking discovery may lead to stronger antibiotics
4. Discovery of natural compounds that could slow blood vessel growth
5. Nanoscopic screening process to speed drug discovery
6. FSU researchers discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
7. New $11 million center to speed production of new compounds for drug discovery
8. Discovery of giant roaming deep sea protist provides new perspective on animal evolution
9. New discovery may enhance MRI scans, lead to portable MRI machines
10. Kidney function discovery sheds light on genetic complexity of disease
11. Discovery of new gene associated with diabetes risk suggests link with body clock
| Copyright © 2003-2012 Bio-Medicine. All rights reserved. ABOUT | CONTACT US | DISCLAIMER | PRIVACY POLICY | TERMS AND CONDITIONS |  |