Navigation Links
Discovery of first motor with revolution motion in a virus-killing bacteria advances nanotechnology
Date:3/20/2013

Scientists have cracked a 35-year-old mystery about the workings of the natural motors that are serving as models for development of a futuristic genre of synthetic nanomotors that pump therapeutic DNA, RNA or drugs into individual diseased cells. Their report revealing the innermost mechanisms of these nanomotors in a bacteria-killing virus and a new way to move DNA through cells is being published online today in the journal ACS Nano.

Peixuan Guo and colleagues explain that two motors have been found in nature: A linear motor and a rotating motor. Now they report discovery of a third type, a revolving molecular motor. Guo pointed out that nanomotors will open the door to practical machines and other nanotechnology devices so small that 100,000 would fit across the width of a human hair. One major natural prototype for those development efforts has been the motor that packages DNA into the shell of bacteriophage phi29, a virus that infects and kills bacteria. Guo's own research team wants to embed a synthetic version of that motor into nanomedical devices that are injected into the body, travel to diseased cells and pump in medication. A major barrier in doing so has been uncertainty and controversy about exactly how the phi29 motor moves. Scientists thought that it worked by rotating or spinning in the same motion as the Earth turning on its axis.

In their ACS Nano paper, Guo, with his team Zhengyi Zhao, Emil Khisamutdinov and Chad Schwartz, challenges that idea. Indeed, they discovered that the phi29 motor moves DNA without any rotational motion. The motor moves DNA with a revolving in the same motion as the Earth revolving around the sun. "The revolution without rotation model could resolve a big conundrum troubling the past 35 years of painstaking investigation of the mechanism of these viral DNA packaging motors," the report states.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Discovery could yield treatment for cocaine addicts
2. Discovery may explain how prion diseases spread between different types of animals
3. Gene discovery reveals importance of eating your greens
4. IU discovery on animal memory opens doors to research on memory impairment diseases
5. Cell discovery could hold key to causes of inherited diseases
6. New scorpion discovery near metropolitan Tucson, Arizona
7. The discovery of a new genus of crustacean and 5 new species
8. A*STAR scientists groundbreaking discovery of nucleus structure crucial to understanding diseases
9. Discovery of sexual mating in Candida albicans could provide insights into infections
10. New discovery in autism-related disorder reveals key mechanism in brain development and disease
11. Discovery of Africa moth species important for agriculture, controlling invasive plants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/25/2015)... and BELLEVUE, Wash. , ... in advanced robotic systems, announced today it will unveil ... ground vehicle (UGV), at the National Tactical Officers Association ... The Guardian S is the first-ever commercially ... of years of research and in-field trials and is ...
(Date:8/20/2015)... Calif. , Aug. 20, 2015   ... focused on improving the user experience and security ... vision technologies, today announced that its TrulySecure™ ... biometric authentication software to be FIDO Certified™. ... TrulySecure for compliance with the FIDO UAF (Universal ...
(Date:8/18/2015)... , Aug. 17, 2015 Research ... addition of the "Global Biometric Authentication & ... - Estimation & Forecast, 2015-2020" report to ... authentication and identification systems market is expected to ... 2015 to 2020 and generate over $25 billion ...
Breaking Biology News(10 mins):Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2
... of two tiny marine algae, a team of scientists ... research in algal physiology, plant biology, and marine ecology. ... Monterey Bay Aquarium Research Institute (MBARI) and the Joint ... effort between MBARI, JGI, and an international consortium of ...
... CREEK, Calif. Scientists from two-dozen research organizations led by ... (JGI) and the Monterey Bay Aquarium Research Institute (MBARI) ... genes enabling them to capture carbon and maintain its ... a team led by Alexandra Z. Worden of MBARI ...
... North Carolina at Chapel Hill School of Medicine have identified ... the most deadly types of cancer, and discovered how a ... and potential treatment apply to a type of brain tumor ... larger group of brain tumors called malignant gliomas, which is ...
Cached Biology News:Genes from tiny marine algae suggest unsuspected avenues for new research 2Genes from tiny marine algae suggest unsuspected avenues for new research 3Genes from tiny marine algae suggest unsuspected avenues for new research 4Genes from tiny algae shed light on big role managing carbon in world's oceans 2Genes from tiny algae shed light on big role managing carbon in world's oceans 3UNC study: Scientists identify chemical compound that may stop deadly brain tumors 2
(Date:8/31/2015)... 31, 2015 Trimb Healthcare AB ("Trimb") today ... YouMedical Group BV ("YouMedical"), a Dutch OTC company with ... sales of approximately EUR 16 million, with solid growth ... "Our ambition is to build a leading international OTC ... that goal. YouMedical gives us a stronger North European ...
(Date:8/31/2015)... ... August 31, 2015 , ... The Food ... food and beverage processors, equipment manufacturers and leaders in the field of academia. ... weighing and formulation for manufacturers of bakery and snacks; beverages; dairy; meat, poultry ...
(Date:8/31/2015)... ... August 31, 2015 , ... Proove Biosciences, Inc. is ... Alliance Annual High Tech Awards. , Now in its 22nd year, this premier ... drive innovation here, across the nation and around the world. The OC Tech Alliance ...
(Date:8/28/2015)... , Aug. 28, 2015 ... addition of the "Global & USA BioSimilar Market ... The highly awaited US Biosimilar market will be ... filigrastim biologic, Zarxio. How will the global market react? ... reveals that biosimilars could save the US economy up ...
Breaking Biology Technology:METTLER TOLEDO Hosts Food Safety Educational Center at 2015 PROCESS EXPO 2Proove Biosciences, Inc. Named a Finalist for 22nd OC Tech Alliance High-Tech Awards for Company of the Year 2Proove Biosciences, Inc. Named a Finalist for 22nd OC Tech Alliance High-Tech Awards for Company of the Year 3Proove Biosciences, Inc. Named a Finalist for 22nd OC Tech Alliance High-Tech Awards for Company of the Year 4Global & USA BioSimilar Market Analysis Report 2015-2021 2Global & USA BioSimilar Market Analysis Report 2015-2021 3
... Mich., April 16 Lycera Corp. today announced it ... which is developing novel small-molecule pharmaceuticals to treat autoimmune ... has received $10 million as a first tranche of ... proceeds in two tranches as specific milestones are met. ...
... Bioscience Inc have successfully implemented Amphora,s PatentSafe solution ... using PatentSafe as a fully electronic lab notebook, ... more efficiently into today,s laboratories but it also ... simply and effectively, saving significant time previously spent ...
... One,Medical, Inc. ("China Sky One Medical" or "the Company") ... company producing over-the-counter,drugs in the People,s Republic of China ... and fiscal year ended December 31,2008. , , ... -- Total revenues increased 104.0% year-over-year to $26.0 million, ...
Cached Biology Technology:Lycera Closes $36 Million Series A Financing 2Lycera Closes $36 Million Series A Financing 3Lycera Closes $36 Million Series A Financing 4Solidus Bioscience Protect their Research and Improve Efficiency With Amphora's PatentSafe Solution 2Solidus Bioscience Protect their Research and Improve Efficiency With Amphora's PatentSafe Solution 3China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 2China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 3China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 4China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 5China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 6China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 7China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 8China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 9China Sky One Medical, Inc. Announces Record Fourth Quarter and Fiscal Year 2008 Results 10
...
... the first biological reagent that ... and not just by inhibiting ... anti-mycoplasma agent that can be ... directly. The cytotoxicity of Mynox ...
... can be used to label ... covalently bound acridinium NHS ester ... presence of hydrogen peroxide. Acridinium ... used as a detection method ...
... mobility shift assay (EMSA) is a powerful ... to as gel shift or gel retardation, ... that when subjected to electrophoresis, free DNA ... The Pierce LightShift Chemiluminescent EMSA Kit is ...
Biology Products: