Navigation Links
Discovery of a molecule that initiates maturation of mammalian eggs can lead to more IVF pregnancies
Date:3/5/2012

Women who have eggs that cannot mature will not become pregnant, and they cannot be helped by in vitro fertilization (IVF). Now researchers at the University of Gothenburg, Sweden, have identified a molecule called Cdk1 that has an important function for mammalian egg maturation. In the future this could lead to an increased rate of successful IVF.

Up to 15% of all women of reproductive age struggle to become pregnant. In vitro fertilization (IVF) can help these women become mothers. However, women who are infertile because their eggs do not mature properly cannot be helped medically, as immature eggs cannot be fertilized. In the future, such patients might be helped as a research group at the University of Gothenburg has found that the Cdk1 molecule has an important function in mammalian egg maturation. Their results have now been published in the journal Human Molecular Genetics.

"This is the first functional evidence that Cdk1 is a key molecule in mammalian egg maturation. If the results can be translated into clinical settings, it could possibly improve the chances of successful IVF treatment for women who today are not becoming pregnant because their eggs do not mature" says Kui Liu, professor at the Department of Chemistry and Molecular Biology, the University of Gothenburg, Sweden.

Kui Liu and his colleagues performed experiments on tissue-specific knockout mice. The results show that when the Cdk1 molecule was removed from eggs of mice, the egg maturation stopped. When the molecule was added again, maturation resumed.

Professor Liu is a professor in molecular biology at the Faculty of Science, University of Gothenburg, since February 2011. His research group specializes in studying the development of female germ cells. In the last few years he has been working on making his results useful for humans.

"We are eager to start tests on human eggs. Hopefully we can apply this in clinics within ten years" says Liu. <
'/>"/>

Contact: Kui Liu
kui.liu@gu.se
46-736-205-064
University of Gothenburg
Source:Eurekalert

Page: 1 2

Related biology news :

1. A*STAR scientists make groundbreaking discovery on stem cell regulation
2. A biodiversity discovery that was waiting in the wings -- wasp wings, that is
3. OHSU discovery may someday lead to prevention and treatment of sudden infant death syndrome
4. Notre Dame researchers report fundamental malaria discovery
5. Discovery of plant nourishing gene brings hope for increased crop seed yield and food security
6. Discovery could help stem smoking-related diseases
7. Georgetown researchers lead discovery expected to significantly change biomedical research
8. New horned dinosaur announced nearly 100 years after discovery
9. Researchers awarded $3.2 million from NIH to pioneer advanced biomolecule discovery technology
10. UGA discovery changes how scientists think about plant cell wall formation
11. Discovery of therapeutic peptides affecting mitochondria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... new study in women suggests that experiencing one or ... high-fat meal can slow the body,s metabolism, potentially contributing ... the previous day,s stressors before giving them a meal ... The scientists then measured their metabolic rate how ... fat and took measures of blood sugar, triglycerides, ...
(Date:7/13/2014)... French . , ... led by the Research Institute of the McGill University ... oral medication is showing significant progress in restoring vision ... this inherited retinal disease that causes visual impairment ranging ... The study is published today in the scientific journal ...
(Date:7/13/2014)... prospect of more effective treatments for cachexia, a profound ... of all cancer patients, raising their risk of death, ... strategies have been tried to reverse the condition, which ... life-saving treatments, but none have had great success. , ... of Nature , led by Bruce Spiegelman, PhD, ...
Breaking Biology News(10 mins):Weighty issue: Stress and high-fat meals combine to slow metabolism in women 2Weighty issue: Stress and high-fat meals combine to slow metabolism in women 3Weighty issue: Stress and high-fat meals combine to slow metabolism in women 4MUHC researcher unveils novel treatment for a form of childhood blindness 2Antibody halts cancer-related wasting condition 2Antibody halts cancer-related wasting condition 3
... basis of all good communication. Stem cells are no exception. ... indication of two-way cellular communication in the miniscule niches of ... , Stem cells require these niches - nest-like microenvironments made ... cells can divide and turn into many types of new ...
... out of an old science fiction movie, but researchers at ... in the treatment of cancer. , The Perspecta® Spatial ... inside a 24-inch dome. The full-color, full-motion system can display ... in true 3D space. , A study led by ...
... in a species of fruit fly that is native to ... 25 years ago. , "This is a clear signal on ... genetic change is going along with it," said Raymond Huey, ... a paper describing the findings, published Aug. 31 in Science ...
Cached Biology News:Stem cells engage in dialogue with the cells that regulate their futures 2Stem cells engage in dialogue with the cells that regulate their futures 3Preliminary study finds holographic imaging system promising for cancer treatment planning 2Evolution of Old World fruit flies on three continents mirrors climate change 2Evolution of Old World fruit flies on three continents mirrors climate change 3
(Date:7/13/2014)... -- The discovery 30 years ago of soccer-ball-shaped carbon ... nanotechnology research. Now, there appears to be a new ... Shanxi University and Tsinghua University in China have shown ... hollow molecular cage similar to a carbon buckyball. It,s ... only a matter of speculationdoes indeed exist. , "This ...
(Date:7/13/2014)... 2014 Deep Research Report on Global and China ... on the current state of the Nano Silver industry ... basic overview of the industry, including definitions, applications and ... market analysis are provided with a focus on history, ... comparison between the international and Chinese situation is also ...
(Date:7/12/2014)... 2014 This report covers ... in the life science industry. Continuous innovation ... reagents market towards remarkable growth. The stakeholders ... of life science reagents. , Brows full ... . , The global life science reagents ...
(Date:7/11/2014)... WEST PALM BEACH, Fla. , July 11, 2014 ... wide variety of high-quality peptides that are used solely ... online. To honor two successful years in business, Maxim ... Performance LLC, has just launched a new and updated ... addition, the research blog section has been updated with ...
Breaking Biology Technology:Researchers discover boron 'buckyball' 2Researchers discover boron 'buckyball' 32014 Nano Silver Industry in Global and China Regions Development Proposals Analysis Available at DeepResearchReports.com 22014 Nano Silver Industry in Global and China Regions Development Proposals Analysis Available at DeepResearchReports.com 3Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 2Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 3Maxim Peptide Celebrates Second Anniversary Online with an Updated Website and Special Deals Section 2
... imagined that the world would be seriously concerned over something ... table, dysprosium was once just another element for chemistry students ... and critically needed materials on the planet. Belonging to ... and other rare earths are used in almost every high-tech ...
... SAN DIEGO, Jan. 11, 2012  Today ELISAlink officially ... life science marketplace. ELISAlink.com will be focused on ... from multiple vendors, in one place. ELISA, an ... medical device used across the world in research ...
... BLUE BELL, Pa., Jan. 11, 2012  Inovio Pharmaceuticals, Inc. (NYSE Amex: ... diseases, announced today that Dr. J. Joseph Kim, President and CEO, will ... Conference. Noble Financial 8th Annual Equity Conference ... Hard Rock Hotel   Inovio Presentation ...
Cached Biology Technology:Berkeley Lab seeks to help US assert scientific leadership in critical materials 2Berkeley Lab seeks to help US assert scientific leadership in critical materials 3Berkeley Lab seeks to help US assert scientific leadership in critical materials 4Berkeley Lab seeks to help US assert scientific leadership in critical materials 5ELISAlink.com ELISA Marketplace and Community Site Coming Soon 2Inovio Pharmaceuticals to Present at Noble Financial 8th Annual Equity Conference 2Inovio Pharmaceuticals to Present at Noble Financial 8th Annual Equity Conference 3
Collected from 8-12 week-old New Zealand or Californian rabbits....
Sterile concentration of Dithiothreitol (DTT) solution in phosphate buffer (pH 7.0). Dilute contents in one vial (10- fold) to 100 ml. For use in liquefying sputum samples....
Silica bead method is an economic method of DNA extraction from agarose...
DTT, 25g...
Biology Products: