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Discovery of a mechanism that controls the expression of a protein involved in numerous cancers
Date:10/20/2010

ould also apply to several other genes. "Our research could serve to explain the production of other proteins with a behaviour similar to MAPK. This mechanism could help us to understand gene expression in general," Marc Therrien concludes.

The breakthrough was made possible by the SOLiD Next Generation Sequencing System manufactured by Life Technologies, which enabled the researchers to view the overall consequences of the elimination of EJC on the expression of all of the cell's genes. "IRIC has adopted a cutting-edge technological infrastructure, without which this kind of work would be impossible," explains Dr. Guy Sauvageau, Chief Executive Officer and Scientific Director of the IRIC. "The Life Technologies sequencing equipment allows us to perform cutting-edge research by quickly obtaining accurate and complete results."


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Contact: Carolyne Lord
carolyne.lord@umontreal.ca
514-343-7282
University of Montreal
Source:Eurekalert

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