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Discovery of a cell that suppresses the immune system
Date:10/4/2010

a population of cells known as follicular T helper cells," explained Dr. Cantor. "We noted that the cells were responsive to osteopontin but also that they expressed what we knew to be the target of suppressor CD8+ T cells."

As next steps, Dr. Cantor and his team will investigate whether defective CD8+ T suppressor cells actually could be a cause of lupus and might serve as a powerful drug target for quieting the immune system response in autoimmunity.


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Contact: Liane Stegmaier
lstegmaier@lupusny.org
212-812-9881
Lupus Research Institute
Source:Eurekalert

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