Navigation Links
Discovery of 100 million-year-old regions of DNA shows short cut to crop science advances
Date:12/5/2012

Scientists have discovered 100 million-year-old regions in the DNA of several plant species which could hold secrets about how specific genes are turned 'on' or 'off'.

The findings, which are hoped will accelerate the pace of research into crop science and food security, are detailed by University of Warwick researchers in the journal The Plant Cell.

By running a computational analysis of the genomes of the papaya, poplar, Arabidopsis and grape species, scientists have uncovered hundreds of conserved non-coding sequences which are found in the DNA of all four species.

These non-coding sequences are not genes, but are located in the promoters upstream of genes and are around 100 DNA base pairs in length.

As the four species have evolved separately for around 100 million years, the fact that these regions have been conserved suggests they play an important role in the plants' development and functioning.

The team at the University of Warwick believe these regions are involved in controlling the expression of the genes they are upstream of - in other words determining whether the genes are turned 'on' or 'off' according to the environmental conditions or developmental stage of the plant.

For example, some genes will be required for defence against pathogens, or others will be required for germination.

Dr Sascha Ott of the Warwick Systems Biology Centre said: "We know that certain genes are conserved between species but we also see that sequences outside of genes are conserved.

"The regions outside genes that we have discovered have been kept for millions and millions of years across four species.

"There must be a reason for this if something has been around for so long it is probably useful in some way.

"We believe it may be because these regions have a very important role to play in how the plant develops and functions.

"It is likely that they are involved in controlling gene expression a vital area for scientists to study as it will ultimately help us to develop crops with specific properties, for example drought tolerance.

"By pinpointing these specific regions, we have zoomed in on what seems to be a very old, and very important, part of DNA.

"We have opened up a short-cut as with this information, the biology community can now focus their experiments on specific regions next to genes which are key targets for plant breeding, and could play an important part in addressing the issue of food security.

"This discovery can be used to underpin future research focusing on working out regulatory codes and link sequence patterns to expression patterns."
'/>"/>

Contact: Anna Blackaby
a.blackaby@warwick.ac.uk
44-024-765-75910
University of Warwick
Source:Eurekalert

Related biology news :

1. Discovery of molecular pathway of Alzheimers disease reveals new drug targets
2. The Journal of Biological Chemistry commemorates an important 1987 discovery
3. GW Research chosen as paper of the week for blood coagulation discovery
4. NIH-funded genetic sequencing tool speeds drug discovery, disease diagnostics
5. Discovery of reprogramming signature may help further stem cell-based regenerative medicine research
6. King Richard III search in new phase after discovery has potential to rewrite history
7. New discovery related to gum disease
8. Cant smell anything? This discovery may give you hope
9. Chemicals today, drugs tomorrow: U-Ms new Center for Drug Discovery
10. Molecular movies may accelerate anti-cancer drug discovery
11. Gene discovery could improve treatment for acute myeloid leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2016)... 31, 2016   ... the "Company") LegacyXChange is excited to release ... soon to be launched online site for trading 100% ... ) will also provide potential shareholders a sense of ... to an industry that is notorious for fraud. The ...
(Date:3/29/2016)... , March 29, 2016 LegacyXChange, ... LegacyXChange "LEGX" and SelectaDNA/CSI Protect are pleased to announce ... used in a variety of writing instruments, ensuring athletes ... originally created collectibles from athletes on LegacyXChange will be ... of the DNA. Bill Bollander , ...
(Date:3/22/2016)... March 22, 2016 ... Sensors Market for Consumer Industry by Type (Image, ... Application (Communication & IT, Entertainment, Home Appliances, ... Forecast to 2022", published by MarketsandMarkets, the ... to reach USD 26.76 Billion by 2022, ...
Breaking Biology News(10 mins):
(Date:6/23/2016)...   Boston Biomedical , an industry leader ... target cancer stemness pathways, announced that its lead ... Designation from the U.S. Food and Drug Administration ... gastroesophageal junction (GEJ) cancer. Napabucasin is an orally ... stemness pathways by targeting STAT3, and is currently ...
(Date:6/23/2016)... -- Houston Methodist Willowbrook Hospital has signed a ... serve as their official health care provider. As ... provide sponsorship support, athletic training services, and most ... athletes and families. "We are excited ... to bring Houston Methodist quality services and programs ...
(Date:6/23/2016)... YORK , June, 23, 2016  The Biodesign ... to envision new ways to harness living systems and ... Modern Art (MoMA) in New York City ... than 130 participating students, showcased projects at MoMA,s Celeste ... Paola Antonelli , MoMA,s senior curator of architecture ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample ... the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application Specialist. ... said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our capacity ...
Breaking Biology Technology: