Navigation Links
Discovery may help scientists boost broccoli’s cancer-fighting power
Date:10/22/2010

URBANA A University of Illinois study has shown for the first time that sulforaphane, the powerful cancer-fighting agent in broccoli, can be released from its parent compound by bacteria in the lower gut and absorbed into the body.

"This discovery raises the possibility that we will be able to enhance the activity of these bacteria in the colon, increasing broccoli's cancer-preventive power," said Elizabeth Jeffery, a U of I professor of human nutrition.

"It's also comforting because many people overcook their broccoli, unwittingly destroying the plant enzyme that gives us sulforaphane. Now we know the microbiota in our digestive tract can salvage some of this important cancer-preventive agent even if that happens," she said.

Although scientists had long theorized that the intestinal microbiota could perform this trick, no one knew it for certain.

Now Jeffery and U of I colleagues Michael Miller and Ren-Hau Lai have proved it by injecting glucoraphanin, the parent compound for sulforaphane, into the ligated lower gut of rats and demonstrating that sulforaphane is present in blood from the mesenteric vein, which flows from the gut to the liver.

"The presence of sulforaphane in measurable amounts shows that it's being converted in the lower intestine and is available for absorption in the body," Jeffery said.

The cecum, the part of the rat's lower gut into which the scientists infused the glucoraphanin, houses bacteria that aid in digestion and metabolism, similar to the human colon.

According to Jeffery, sulforaphane is an extremely potent cancer-fighting agent. "The amount that you get in three to five servings a weekthat's less than one daily serving of broccoliis enough to have an anti-cancer effect. With many of the other bioactive foods you hear about, vast amounts are required for a measurable outcome."

Sulforaphane also has anti-inflammatory properties, which are interesting to sci
'/>"/>

Contact: Phyllis Picklesimer
p-pickle@illinois.edu
217-244-2827
University of Illinois College of Agricultural, Consumer and Environmental Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Chemical equator discovery will aid pollution mapping
2. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
3. Groundbreaking discovery may lead to stronger antibiotics
4. Discovery of natural compounds that could slow blood vessel growth
5. Nanoscopic screening process to speed drug discovery
6. FSU researchers discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
7. New $11 million center to speed production of new compounds for drug discovery
8. Discovery of giant roaming deep sea protist provides new perspective on animal evolution
9. New discovery may enhance MRI scans, lead to portable MRI machines
10. Kidney function discovery sheds light on genetic complexity of disease
11. Discovery of new gene associated with diabetes risk suggests link with body clock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... EyeLock, Inc. , a market leader of iris-based identity authentication ... to the new role of Senior Vice President of Mobile ... mobile platforms and wearable solutions for EyeLock,s technologies. Gerber brings ... semiconductor industry to his role at EyeLock, with expertise in ...
(Date:12/24/2014)... in December 2014, the 1U™ app has helped ... remember their usernames and passwords through replacing the antiquated system ... people who have struggled to remember usernames and passwords, ... on redefining identity, announced today that it is offering the ...
(Date:12/22/2014)... DUBLIN , Dec. 22, 2014 Research and ... the addition of the "The Global Watermarking ... http://photos.prnewswire.com/prnh/20130307/600769 ... global digital media watermarking and fingerprinting markets. Watermarking ...
Breaking Biology News(10 mins):EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3The Global Watermarking and Fingerprinting Markets 2
... meteorite fragments that fell on a frozen lake in ... life,s handedness why living things only use molecules ... evidence to date that liquid water inside an asteroid ... forms of some common protein amino acids in meteorites. ...
... days following the 2010 Deepwater Horizon oil spill, methane-eating ... the methane that gushed, along with oil, from the ... scientific curiosity: Prior to the oil spill, scientists had ... area. Now researchers at MIT have discovered a ...
... available in German . , Leipzig. Fungi ... threads. However, these networks have surprising functions. Only a few ... (UFZ) discovered that bacteria travel over the fungal threads through ... a highway. Now, together with British colleagues from the University ...
Cached Biology News:NASA and university researchers find a clue to how life turned left 2NASA and university researchers find a clue to how life turned left 3NASA and university researchers find a clue to how life turned left 4NASA and university researchers find a clue to how life turned left 5Newfound gene may help bacteria survive in extreme environments 2Newfound gene may help bacteria survive in extreme environments 3Newfound gene may help bacteria survive in extreme environments 4Contaminant transport in the fungal pipeline 2Contaminant transport in the fungal pipeline 3Contaminant transport in the fungal pipeline 4
(Date:1/23/2015)... Biofertilizers stimulate microbial activities in soil. These microorganisms generate ... activities in the soil or in the rhizosphere. The ... on reducing environmental pollution and on reducing the usage ... the bio fertilizers market with analysis and forecasting of ...
(Date:1/22/2015)... , Jan. 22, 2015  Transwestern | RBJ today announces the ... office space for Shire a leading biopharmaceutical company, at Two ... | RBJ,s Robert Richards , president, and Brian ... for the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... Johnston, RI (PRWEB) January 22, 2015 ... State , The growing team of brand-neutral, independent consultants, ... CIO Philip Rogers explained that over the years, his ... including , Moroso, Town of Plainfield, as well as ...
(Date:1/22/2015)... 2015 Controlled Substance Compliance Services (CSCS), ... companies check the legal requirements around using controlled substances ... , As their international operations expand and become ... solutions built as a result of the first phase ...
Breaking Biology Technology:Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 2Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 3Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 4Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2Global Compliance Service for Controlled Substances to Expand to China 2
... GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX), an Atlanta-based biopharmaceutical ... Human Immunodeficiency Virus (HIV) infections, today announced its financial ... GeoVax reported a net loss of $375,852 ... 30, 2011, compared to $644,666 ($0.04 per share) for ...
... Fla., Nov. 10, 2011 Theravalues, a ... product, impacts positively on the prevention of heart failure ... During the human clinical trial started with the registration ... Hospital Organization Kyoto Medical Center and University of Shizuoka, ...
... MEMPHIS, Tenn., Nov. 10, 2011   ACORN Research ... in personalized medicine and translational research, by offering ... industry and academic research through its partnership with ... ACORN Research is able to provide CRO services ...
Cached Biology Technology:GeoVax Labs, Inc. Announces Nine Month 2011 Financial Results 2GeoVax Labs, Inc. Announces Nine Month 2011 Financial Results 3GeoVax Labs, Inc. Announces Nine Month 2011 Financial Results 4GeoVax Labs, Inc. Announces Nine Month 2011 Financial Results 5Theravalues Confirms Beneficial Effects of Theracurmin™ on Diastolic Function in Hypertensive Patients 2ACORN Research, LLC Announces Partnership with AdeptBio, LLC 2
... Microplate Handler is a high-capacity, plug-and-play ... BioTeks washers, readers and liquid handling ... ultimate flexibility and intuitive and powerful ... to single devices or linking several ...
... rapid analytical to medium scale affinity purification ... vectors. Sufficient reagents are provided for purification ... under native or denaturing conditions. Crude samples ... retains STag fusion proteins. After unbound proteins ...
... ,Components g/500 ml: ,Tryptone ... chloride 2.5 ,Agar 6.0 ,S-Gal ... ,IPTG 0.025 ,Kanamycin 0.0175 ... complete growth medium containing S-Gal ...
Useful for determination of glucose and ATP. Packaging: Package sizes are based on hexokinase units. Preparation Unit Definition: One unit will phosphorylate 1.0 mol of D -glucose per min at pH ...
Biology Products: