Navigation Links
Discovery may help scientists boost broccoli’s cancer-fighting power
Date:10/22/2010

URBANA A University of Illinois study has shown for the first time that sulforaphane, the powerful cancer-fighting agent in broccoli, can be released from its parent compound by bacteria in the lower gut and absorbed into the body.

"This discovery raises the possibility that we will be able to enhance the activity of these bacteria in the colon, increasing broccoli's cancer-preventive power," said Elizabeth Jeffery, a U of I professor of human nutrition.

"It's also comforting because many people overcook their broccoli, unwittingly destroying the plant enzyme that gives us sulforaphane. Now we know the microbiota in our digestive tract can salvage some of this important cancer-preventive agent even if that happens," she said.

Although scientists had long theorized that the intestinal microbiota could perform this trick, no one knew it for certain.

Now Jeffery and U of I colleagues Michael Miller and Ren-Hau Lai have proved it by injecting glucoraphanin, the parent compound for sulforaphane, into the ligated lower gut of rats and demonstrating that sulforaphane is present in blood from the mesenteric vein, which flows from the gut to the liver.

"The presence of sulforaphane in measurable amounts shows that it's being converted in the lower intestine and is available for absorption in the body," Jeffery said.

The cecum, the part of the rat's lower gut into which the scientists infused the glucoraphanin, houses bacteria that aid in digestion and metabolism, similar to the human colon.

According to Jeffery, sulforaphane is an extremely potent cancer-fighting agent. "The amount that you get in three to five servings a weekthat's less than one daily serving of broccoliis enough to have an anti-cancer effect. With many of the other bioactive foods you hear about, vast amounts are required for a measurable outcome."

Sulforaphane also has anti-inflammatory properties, which are interesting to sci
'/>"/>

Contact: Phyllis Picklesimer
p-pickle@illinois.edu
217-244-2827
University of Illinois College of Agricultural, Consumer and Environmental Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Chemical equator discovery will aid pollution mapping
2. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
3. Groundbreaking discovery may lead to stronger antibiotics
4. Discovery of natural compounds that could slow blood vessel growth
5. Nanoscopic screening process to speed drug discovery
6. FSU researchers discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
7. New $11 million center to speed production of new compounds for drug discovery
8. Discovery of giant roaming deep sea protist provides new perspective on animal evolution
9. New discovery may enhance MRI scans, lead to portable MRI machines
10. Kidney function discovery sheds light on genetic complexity of disease
11. Discovery of new gene associated with diabetes risk suggests link with body clock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... Channel has resulted in the removal of many top ... barrel, for increasing amounts of shellfish to make up ... species at the head of the food chain are ... completely., These are some of the findings of a ... association with international non-profit research organization WorldFish. They analysed ...
(Date:7/10/2014)... start-up company housed at NJIT,s business incubator, received a ... that surgeons will use to staunch bleeding during brain ... surgical site, and the natural bio-polymer solutions in the ... within 30 seconds. , The gel can shorten ... translate into less time for the patient,s skull to ...
(Date:7/10/2014)... today that Courtney Aldrich, Ph.D., will head the ... as editor-in-chief. With the first issue slated for ... meet a growing demand for a place to ... vision is to develop a journal focused on ... science that advances the field and lays the ...
Breaking Biology News(10 mins):Overfishing in the English Channel leaves fisherman scraping the bottom of the barrel 2Overfishing in the English Channel leaves fisherman scraping the bottom of the barrel 3A start-up at NJIT develops bleeding-control gel for brain surgery 2ACS Infectious Diseases: Unique chemistry journal names editor 2
... not only supplies key nutrients, it may also influence hormone ... a new study led by researchers at the University of ... diet in human evolution. The research is the ... phytoestrogens, and behavior in wild primates in this case, ...
... 19, 2012 Deciphering what causes the brain cell degeneration ... But a team led by scientists from The Scripps Research ... brain cells in a mouse model of Parkinson,s disease. The ... be useful in preventing the actual condition. The team, ...
... MD, MPH, has been named the winner of the $100,000 ... 6,500 online votes from people across the globe determined the ... sequencing of newborns, emerged as the winner after six weeks ... for creating this competition and I am delighted to win. ...
Cached Biology News:Estrogenic plants linked to altered hormones, possible behavior changes in monkeys 2Estrogenic plants linked to altered hormones, possible behavior changes in monkeys 3Scripps Research Institute team identifies a potential cause of Parkinson's disease 2Scripps Research Institute team identifies a potential cause of Parkinson's disease 3Research gets real - Public votes determine winner of $100,000 research prize 2
(Date:7/10/2014)... Mass. (PRWEB) July 10, 2014 Terascala, ... today announced that Alan Swahn, a former vice president ... executive team as vice president of marketing. Terascala’s software ... Dell and NetApp create the highest performance and most ... been appointed to guide Terascala’s channel expansion and broaden ...
(Date:7/10/2014)... July 10, 2014 Robert Harman, DVM, Founder ... company, is proud to announce the relaunch of his highly ... a new series called “ What are Stem Cells ?” ... honest and straightforward foundation in the basics of stem cell ... on the right type of treatment when considering regenerative medicine. ...
(Date:7/10/2014)... EvoDerma ’s NOOME Anti-Aging Motion has been upgraded ... with a second treatment cup to help prevent and smooth ... is thinner on the edges for a softer contact with ... uneven surfaces on the face, neck and décolleté. Choose to ... areas such as the cheeks and neck, or opt for ...
(Date:7/10/2014)... POINT, Ind. , July 10, 2014 ... expanded its use of capnography for respiratory ... growing group of healthcare leaders in embracing ... measures how effectively patients are breathing and ... depression occurs. By measuring the amount of ...
Breaking Biology Technology:Terascala Expands Executive Team 2Terascala Expands Executive Team 3Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2
... 2011 Halozyme Therapeutics, Inc. (NASDAQ: ... products targeting the extracellular matrix for the ... financial results for the third quarter of 2011 and ... ) "The past few months highlight the ...
... 2011 BIOCOM, the trade group representing Southern California,s ... partnered to tell the biotechnology story from discovery through ... glimpse into the exciting and innovative world of medical ... to patients around the globe. "Tomorrow,s Health," a new ...
... 2011 Note: numbers in square brackets relate ... available for interview. Investment fund manager Porton Group ... a court battle with 3M over the multi-national company,s failure ... The High Court in London found 3M was "in material ...
Cached Biology Technology:Halozyme Therapeutics Reports Third Quarter 2011 Financial Results 2Halozyme Therapeutics Reports Third Quarter 2011 Financial Results 3Halozyme Therapeutics Reports Third Quarter 2011 Financial Results 4Halozyme Therapeutics Reports Third Quarter 2011 Financial Results 5Halozyme Therapeutics Reports Third Quarter 2011 Financial Results 6Halozyme Therapeutics Reports Third Quarter 2011 Financial Results 73M Forced to Pay for Breach of Obligations Over MRSA - High Court 23M Forced to Pay for Breach of Obligations Over MRSA - High Court 33M Forced to Pay for Breach of Obligations Over MRSA - High Court 4
HyPro 20 system for slide hybridization. 20 slide capacity. Active vibration system, slide rack and humidity chamber. Ideal for microarray and in situ hybridization....
... PBL's bioassays for interferons are cytopathic effect inhibition ... Sample types include; tissue culture supernatents; serum ... these assays, one unit is defined as the ... the cytopathic effect of viral infection by 50%. ...
Request Info...
Request Info...
Biology Products: