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Discovery demonstrates potential MS therapy could kill brain cells
Date:5/6/2011

mmune diseases, these T-cells could keep autoimmune diseases under control. Work with lab models that had MS and were treated with T-cells was promising. However, recent studies of human cells have shown humans have different subpopulations of T-cells some of which do not have a regulatory function.

Giuliani and Haile worked with different subpopulations of T-cells and discovered some were toxic to neurons. Giuliani and his colleague are the first medical researchers to demonstrate that activating a specific type of T-cell can kill brain cells.

They want to continue their work in this area to determine what causes some T-cells to behave this way.

"We want to take the research further. We want to continue this story in an attempt to try and solve the mystery."


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Contact: Raquel Maurier
raquel.maurier@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

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