Navigation Links
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
Date:12/2/2010

lly large, suggesting that the mosquitoes' fluid excretory function had been impeded. The researchers also found that in these mosquitoes, egg development, whose success is dependent on blood digestion, was severely inhibited.

"Our finding is exciting because it gets to the very core of what a vector of diseases is all about," said Alexander Raikhel, a distinguished professor of entomology, whose lab led the study. "We can now knock down a series of events starting with the digestion of blood and proceeding all the way to egg maturation simply by eliminating this small molecule, miR-275. In tropical areas of the world, where dengue and yellow fever are often leading causes of hospitalization and death among adults and children, a reduction in the number of Aedes aegypti mosquitoes would be tremendously beneficial."

Study results appear this week in the online edition of the Proceedings of the National Academy of Sciences.

Next in this line of work, Raikhel's lab plans to focus on determining which genes miR-275 targets, what roles these genes play in blood digestion and egg development, and what mechanism underlies the activation and deactivation of miR-275.

Bart Bryant, the first author of the research paper and a postdoctoral researcher in Raikhel's lab, explained that the research team knocked down or "depleted" the miR-275 with an "antagomir" a small synthetic RNA molecule that in this research study binds with miR-275, preventing it from doing its job of allowing blood digestion and egg development to proceed.

"We think our work has opened the door for exploring how microRNAs regulate critical physiological functions specific to vectors that transmit deadly disease pathogens," Bryant said.


'/>"/>

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Strange discovery: Bacteria built with arsenic
2. Mystery dissolves with calcium pump discovery
3. In new novel, secret discovery threatens company and damages love affair
4. New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
5. Gene discovery suggests way to engineer fast-growing plants
6. TB-drugome provides new targets for anti-tuberculosis drug discovery
7. Discovery of an anti-inflammatory substance
8. A discovery could be important for the therapy of lymphoma and leukemia
9. AACR announces new journal, Cancer Discovery
10. Swan song of space shuttle Discovery to carry 2 payloads built by CU-Boulder
11. Discovery of taste receptors in the lungs could help people with asthma breathe easier
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population
(Date:3/12/2015)... , March 12, 2015 The mascots of ... Children,s Hospital, part of Wake Forest Baptist Medical Center. ... for the 2015 ACC Men,s Basketball Tournament. Young patients ... them and getting their autographs. Brenner Children,s ... It is the only children,s hospital in northwest ...
(Date:3/11/2015)... 11, 2015 Research and Markets ( ... "Access Control Market by Product, Application & By Geography ... to their offering. , This report predicts ... $10.4 billion by 2020, with an estimated CAGR of ... the products types such as contact cards & readers, ...
(Date:3/10/2015)... BOULDER, Colo. , March 10, 2015 ... Space Flight "Personalized Medicine in Human ... Ph.D. and Thomas J. Goodwin , Ph.D. was ... articles of the past two years. Specifically, ... three most downloaded scientific papers published in 2013 and ...
Breaking Biology News(10 mins):Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2
... In this week's Analytical Chemistry, scientists at Indiana ... sperm cells to follow the weakest of scents. ... some sperm cells still found their mark. , ... response to a chemical gradient) can be downloaded ...
... predict which smokers using the nicotine patch are likely to ... probability of success in quitting cigarettes, according to the results ... of Clinical Pharmacology and Therapeutics. , The blood ... nicotine is metabolized, may eventually be performed non-invasively using saliva ...
... Unlike the Three Musketeers who lived by the motto ... to do their own thing. For years, debate swirled ... on a central growth regulatory module. Now, the cooperation ... for Biological Studies. They show that each hormone acts ...
Cached Biology News:Even when faint, ovary scent draws sperm cells 2Blood test predicts success of quitting smoking using the nicotine patch 2Computational analysis shows that plant hormones often go it alone 2Computational analysis shows that plant hormones often go it alone 3
(Date:3/26/2015)... (PRWEB) March 26, 2015 "In America," the ... the United States that is hosted by legendary film actor ... topic of botany in an upcoming segment. , Botany ... in reality it is actually quite a bit more complicated ... of different types of living organisms, from the smallest bacteria ...
(Date:3/25/2015)... pharmaceutical market is one of the most attractive ... absolute size, plus a growing economy and increasing government ... Monitor International. The Russian market is set to grow ... with growth estimates around 10-15% annually reaching an approximate ... About Green Cross Green Cross provides total ...
(Date:3/25/2015)... -- Optimal Research, LLC has been nominated as a ... Clinical Site or Trial Network". This is ... as a nominee in this ViE award category at ... in 2014. The ViE awards were created to honor ... contributions of companies and individuals in the vaccine industry. ...
(Date:3/25/2015)... March 25, 2015 Laboratory workers ... Balances and Analytical Balances to get best-performing features ... of weighing balances from the trusted brand include: ... increase your efficiency by providing a large ... samples. Weighing modes include parts counting, percent weighing, ...
Breaking Biology Technology:Optimal Research Nominated 2015 Vaccine Industry Excellence (ViE) Award 2New Economical Top-Loading and Analytical Symmetry Balances from Cole-Parmer 2
... Healthcare Distribution Management Association (HDMA), the national association representing ... association as Senior Vice President of Government Affairs. In ... federal and state legislative and regulatory initiatives. ... array of evolving laws and regulations that have a ...
... Jan. 4, 2011 When pregnant women need medications, ... fetus. Although some drugs are clearly recognized to cause ... are generally recognized as safe, surprisingly little is known ... Children,s Hospital Boston Informatics Program (CHIP) have created a ...
... Neogen Corporation (Nasdaq: NEOG ) announced today that ... which ended Nov. 30, increased 33% from the previous year,s ... or $0.26 per share, compared to the prior year,s $0.20. ... to the prior year,s $35,251,000. Year-to-date revenues for the first ...
Cached Biology Technology:Healthcare Distribution Management Association Names Patrick Kelly New Senior Vice President, Government Affairs 2Model Predicts a Drug's Likelihood of Causing Birth Defects 2Model Predicts a Drug's Likelihood of Causing Birth Defects 3Neogen Reports 33% Increase in Net Income 2Neogen Reports 33% Increase in Net Income 3Neogen Reports 33% Increase in Net Income 4Neogen Reports 33% Increase in Net Income 5
Mouse monoclonal antibody raised against a full length recombinant LDB3. NCBI Entrez Gene ID = LDB3...
...
Mouse monoclonal antibody raised against a partial recombinant WDR5. NCBI Entrez Gene ID = WDR5...
... Polyclonal Antibody against Nonmuscle Myosin II ... Antibody (Stored in TBS + 0.03% ... the peptide SDVNETQPPQSE corresponding to the ... isoform B (MHC-B) This antibody is ...
Biology Products: