Navigation Links
Discovery: Yeast make plant hormone that speeds infection

venous lines are at risk, as the fungi can grow on those devices and enter the body. Because of the lack of an effective treatment, the mortality rate for some systemic fungal infections is nearly 45 percent. Prusty Rao's lab explores the basic biology of yeast to better understand the processes of fungal infections and to identify potential targets for new drug development.

Before fungi begin to infect a host, they first undergo a dramatic physical change and grow filaments that look like twigs on a leafless tree. The hormone indole-3-acetic acid (IAA) regulates how plants grow, causing them to extend shoots towards sunlight. Previous work by Prusty Rao and others has shown that yeast take-up IAA from the environment to stimulate the growth of filaments. In the current study, Prusty Rao's team found that yeast also produce IAA themselves and secrete it into the environment around them. In this manner, the ongoing secretion and uptake of IAA presumably becomes a feedback loop giving the yeast information about the number of yeast nearby. If there are many yeast secreting IAA, then there is more in the environment to take up.

Furthermore, Prusty Rao's team found that when the concentration of IAA reached a certain threshold, the fungus began to change shape and grow filaments (see figure), providing "strong support" for a connection between the yeasts' production of IAA and fungal infection.

"If there is just one yeast cell sitting under your toe nail, then it won't be a problembut if there are a thousand yeast cells there, then they can begin to filament and cause infection," Prusty Rao noted. "We believe the data show that IAA plays a role in the yeast's ability to know when there are sufficient numbers of them in close enough proximity to try and infect a host, be it a plant or a person."


Contact: Michael Cohen
Worcester Polytechnic Institute

Page: 1 2

Related biology news :

1. An electrifying discovery: New material to harvest electricity from body movements
2. Gene function discovery: Guilt by association
3. New year, new vitamin C discovery: It cures mice with accelerated aging disease
4. You had me at hello: Frisky yeast know who to shmoo after 2 minutes
5. Genetic patterns rise from huge yeast samples
6. Scientists find new genes for cancer, other diseases in plants, yeast and worms
7. Sugar-hungry yeast to boost biofuel production
8. 2010 Yeast Genetics and Molecular Biology Meeting
9. Charles Drew cancer studies with yeast yield excellent results
10. Helpful yeast battles food-contaminating aflatoxin
11. Yeast missing sex genes undergo unexpected sexual reproduction
Post Your Comments:
Related Image:
Discovery: Yeast make plant hormone that speeds infection
(Date:9/30/2015)... , Sept. 30, 2015  The global glucose monitoring device ... 2015. So says a new report on the industry from ... segment dominate the market, followed by continuous glucose monitoring and ... on the market for these products in its latest report, ... , ...
(Date:9/28/2015)... , Sept. 28, 2015 ... today that its expedited traveler service is ... platform transforms travel, bringing a frictionless experience, ... members. "CLEAR offers our travelers ... customer service," said Jim Smith , ...
(Date:9/28/2015)... , September 28, 2015 ... Component (Hardware & Software), Product (Scanner & Others), Application ... & Defense, & Others) & Geography Global - Forecast ... expected to reach USD 3627.90 Million by 2020, at ... Browse 65 market data T ables ...
Breaking Biology News(10 mins):
... and Nanosystems Research (IBN), Austrian Academy of Sciences ... of Technology, Cambridge, USA report the study of ... Designer Lipid-Like Peptide Surfactants” in the May 30th ... Their findings not only help us to ...
... a chronic and progressive lung disorder from which most patients ... by the insidious onset of dyspnea or cough and usually ... coworkers present in an article published in the online, open-access ... that a subset of IPF patients has a short duration ...
... chronic lung disease typically characterized by the slow but ... patients live about five years after diagnosis. However, according ... online journal PLoS ONE, a subset of patients with ... progression to complete pulmonary failure and death without a ...
Cached Biology News:
(Date:10/9/2015)...  Pulmatrix, Inc., (NASDAQ: PULM ) will be webcasting ... th Annual BIO Investor Forum on Tuesday, ... --> th Annual BIO Investor Forum ... pm EDT). --> Pulmatrix will be presenting ... on Thursday, October 15, 2015 at 8:30 am EDT. Additionally, ...
(Date:10/8/2015)... SAN DIEGO , Oct. 8, 2015 /PRNewswire/ ... oncology company developing new treatments for cancer and ... Chief Executive Officer, will be presenting at the ... Las Vegas :Event:Aegis Capital Corporation 2015 ... PDTLocation:Brahms 2 room, The Encore @ The Wynn ...
(Date:10/8/2015)... 2015 .   ... Goldman Small Cap Research, a stock market ... microcap sectors, announced today that it has published ... Inc. (OTCQB - PMCB), a publicly traded, clinical ... treatments for cancer and diabetes. To view the ...
(Date:10/8/2015)... 2015 /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: REPCF) (TSX.V: ... the development of autologous cell therapies, today announced its schedule ... place in the month of October: Stem ... RepliCel will be presenting at the annual Partnering Forum, ... to be held October 7-9 in La ...
Breaking Biology Technology:
... sole U.S. supplier of 3M electrosurgical grounding pads ... ... Industries, Inc. and,3M Health Care announce an exclusive license and supply ... agreement,Medline has acquired the exclusive license and sales rights in the ...
... Eastern Time Today, GAITHERSBURG, Md., March 6 ... and corporate progress for,the full year ended December 31, ... further demonstrated that Iomai,s,vaccine and immunostimulant patches can be ... chief executive officer,of Iomai. "This lays the foundation for ...
... (Pink Sheets: VXGN), a biopharmaceutical company, today reported its,year ... a view to,ensuring that stockholders have the most current ... with Raven biotechnologies,inc. VaxGen,s Board of Directors has set ... of Stockholders to vote on the proposed merger., ...
Cached Biology Technology: