Navigation Links
Dietary supplements discouraged for prostate cancer patients

Prostate-specific dietary supplements should not be taken during radiation therapy treatments because they have been shown to increase the radiosensitivity of normal prostate cell lines, leading to normal tissue complications, according to a study in the March issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

Many prostate cancer patients choose to take nutritional supplements to improve or increase sexual potency and alleviate symptoms associated with poor prostate health. Some studies show that about half of prostate cancer patients use an herbal or dietary supplement and most do so without discussing it with their doctor.

Researchers at William Beaumont Hospital in Royal Oak, Mich., sought to determine if three widely used commercial prostate-specific dietary supplements changed the radiosensitivity of normal prostate and/or androgen-positive and -negative prostate tumor cell lines. There have been published reports of negative clinical effects for some tumor sites from the use of certain dietary supplements after chemotherapy, but the effect of dietary supplements on radiation therapy treatments is not well-known.

The study authors found that the cell growth and radiosensitivity of the malignant tumor cells were not affected by any of the supplements, but two of the supplements inhibited the growth rate of the normal prostate cell lines while a third supplement also increased the cellular radiosensitivity of some normal cell lines by inhibiting DNA repair.

"Cancer patients turn to supplements to aid in their treatments for a variety of reasons, but this study proves that what some patients believe is helping them may actually be harming them," Brian Marples, Ph.D., senior author of the study and a radiobiologist at William Beaumont Hospital and clinical research professor at Oakland University William Beaumont School of Medicine, said. "It is very important for all patients to discuss any type of supplement they may be taking with their physician and especially important for prostate cancer patients receiving radiation therapy as this study shows that it may be negatively affecting the effectiveness of their treatments."


Contact: Beth Bukata
American Society for Radiation Oncology

Related biology news :

1. Dietary factors influence ovarian cancer survival rates
2. Researchers develop dietary formula that maintains youthful function into old age
3. Even small dietary reductions in salt could mean fewer heart attacks, strokes and deaths
4. Dietary supplements manufacturers gain new tool to help ensure quality products
5. Two dietary oils, two sets of benefits for older women with diabetes
6. Following the dietary guidelines may slow heart disease in women
7. Desert woodrats switch one dietary poison for another
8. Desert woodrats switch one dietary poison for another
9. Results of the third school nutrition dietary assessment study published
10. Annual Bibliography of Significant Advances in Dietary Supplement Research 2007
11. The dietary supplement genistein can undermine breast cancer treatment
Post Your Comments:
(Date:9/24/2015)... 24, 2015 Publiceringsförbud ... Kerv ( ), ... idag världens första kontaktlösa betalningsring på ... 000 GBP för massproduktion via crowdfunding.  ... , Kerv-bärare kan göra direkta ...
(Date:9/10/2015)... 10, 2015 Report Details ... Selling Opportunities and Revenue Prospects to Help You ... biologics, especially new drug classes? Get the latest ... with exclusive market data and industry knowledge, benefitting ... results, opportunities and sales predictions. Visiongain,s new ...
(Date:9/10/2015)... Sept. 10, 2015 Pursuant Health has ... to create an interactive, image-based health risk assessment ... wellness kiosk.  The unique assessment quantifies user results ... that suggests an individual,s biological age based on ... measured by the kiosk. Comprised of ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... , ... October 12, 2015 , ... ... that Dr. Srini Srinivasan, has joined the firm as a Premier Expert consultant. ... stature enable them to bring extraordinary value to the company's clients. Premier ...
(Date:10/11/2015)... ... 2015 , ... Intelligent Implant Systems, LLC is pleased to ... have been completed with this new posterior thoracolumbar spinal fusion system. The surgeries ... the Carolinas. The Revolution™ Spinal System pioneers a new approach to lumbar ...
(Date:10/9/2015)... ANNAPOLIS, Md. , Oct. 9, 2015 ... entered into the Congressional Record her statement recognizing the ... celebrated October 11-17. IPAW is sponsored by the ... companies, and is designed to:   , Raise ... contributions of plasma donors in saving and improving lives ...
(Date:10/9/2015)...  DePuy Synthes Trauma* announced today the U.S. launch ... Technology**, the only pre-hydrated demineralized cancellous bone tissue matrix ... ankle, hand and wrist), including fusion, and for filling ... 2015 Orthopaedic Trauma Association (OTA) Annual Meeting. ... bone growth) and osteoinductive 2,3 (stimulates new bone ...
Breaking Biology Technology: