Navigation Links
Dietary amino acids improve sleep problems in mice with traumatic brain injury
Date:12/11/2013

PORTLAND, Ore. Scientists have discovered how to fix sleep disturbances in mice with traumatic brain injuries a discovery that could lead to help for hundreds of thousands of people who have long-term and debilitating sleep and wakefulness issues after they suffer concussions.

What scientists found helpful was giving the mice something all humans produce from foods in their normal diets something called branched chain amino acids.

"If further research confirms what this study suggests, we could develop a dietary supplement of these amino acids that could be a viable therapy to help people after a concussion," said Miranda Lim, M.D., Ph.D., a neurologist and sleep medicine specialist at the Portland VA Medical Center and an assistant professor of pulmonary and critical care medicine, neurology and behavioral neuroscience at Oregon Health & Science University. Lim is the first author of the study, published online today in Science Translational Medicine.

Lim performed this research during her sleep medicine fellowship at the University of Pennsylvania. Senior authors on the study are Akiva S. Cohen, Ph.D., a neuroscientist at The Children's Hospital of Philadelphia and Allan I. Pack, M.D., Ph.D., director of the Center for Sleep and Circadian Neurobiology in the Perelman School of Medicine at the University of Pennsylvania.

Nearly 2 million people a year in the United States suffer a traumatic brain injury, including concussion, which is considered a mild traumatic brain injury. Sleep disturbances are common in those with TBI; some studies show up to 72 percent of TBI patients including those who've suffered concussions have sleep problems.

Sleep problems impair attention and memory formation in TBI patients, who have a higher rate of functional disability and a higher cost of rehabilitation.

"Sleep disturbances, such as excessive daytime sleepiness and nighttime insomnia, disrupt quality of life a
'/>"/>

Contact: Todd Murphy
murphyt@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Enrollment in SNAP does not substantially improve food security or dietary quality
2. Studies support population-based efforts to lower excessive dietary sodium intakes
3. Dietary flexibility may have helped some large predators survive after last ice age
4. National survey highlights perceived importance of dietary protein to prevent weight gain
5. Canadians support interventions to reduce dietary salt
6. International study: Excess dietary salt may drive the development of autoimmune diseases
7. Dietary shifts driving up phosphorus use
8. New health-economic model shows benefits of boosting dietary calcium intake
9. Research provides new insights into dogs natural feeding behavior and finds they target a daily dietary intake that is high in fat
10. Neuroprotective dietary supplements for chronic spinal cord injury
11. Zebrafish research shows how dietary fat regulates cholesterol absorption
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... the repeated climatic shifts over the last 120,000 ... diversity, a team of researchers led by City ... developed a new biodiversity metric called "phylogeographic endemism." ... genetic variation within species is restricted in geographical ... biology, and 14 other researchers from institutions in ...
(Date:8/29/2014)... as the prolific bloomer Emiliania huxleyi , can ... The finding contradicts the common view that E. ... scarce supplies of thiamine in the ocean to survive. ... the ocean," says CIFAR Senior Fellow Alexandra Worden ... with CIFAR fellows John Archibald (Dalhousie University), ...
(Date:8/28/2014)... mobile app called TX Invasives is now available from ... of Texas at Austin for identifying harmful non-native plant, ... species in the United States cause about $137 billion ... agricultural crops, clog waterways, kill native plants and more. ... app for reporting where invasive species occur, we,re more ...
Breaking Biology News(10 mins):CCNY team defines new biodiversity metric 2Not all phytoplankton in the ocean need to take their vitamins 2Not all phytoplankton in the ocean need to take their vitamins 3Mobile app makes ID of harmful plants, insects in Texas a snap 2
... You may think your lack of resolve to get off ... University researchers have discovered it may be you are missing ... working with healthy, specially-bred mice, some of which had two ... the protein AMP-activated protein kinase (AMPK), an enzyme that is ...
... found a reason why men,s ring fingers are generally ... reverse usually holds true for women. The finding ... and disease, which may be useful for customizing treatments ... Writing this week in the Proceedings of ...
... CA September 4, 2011 Starting with normal skin ... first stem cells from endangered species. Such cells could eventually ... some species, possibly saving them from extinction, or to bolster ... description of the accomplishment appeared in an advance online edition ...
Cached Biology News:McMaster researchers find missing genes may separate coach potato from active cousin 2Male-female ring finger proportions tied to sex hormones in embryo; may offer health insights 2Male-female ring finger proportions tied to sex hormones in embryo; may offer health insights 3Scripps Research scientists produce first stem cells from endangered species 2Scripps Research scientists produce first stem cells from endangered species 3Scripps Research scientists produce first stem cells from endangered species 4
(Date:8/28/2014)... August 28, 2014 Best Sanitizers, Inc., ... the food processing industry, is asking industry professionals to ... comparison of the E2 soap they’re currently using to ... Soap . Hand hygiene is critical to fighting ... processing environment. Six key criteria are identified to evaluate ...
(Date:8/28/2014)... research platform uses a laser to measure ... stress and heating, an approach likely to ... and batteries., This new technique, called nanomechanical ... and the surface stress of microscale structures ... the merits of surface-stress influence on mechanical ...
(Date:8/28/2014)... PA (PRWEB) August 28, 2014 The ... create a culture that will allow individuals to perform ... becoming increasingly important for employers looking to compete in ... industries are embracing this trend, as the sector increasingly ... of a company, which will have real results on ...
(Date:8/28/2014)... Sterlitech is proud to announce that ... stable of products . These additional products ... include membrane filters with surface charges. , ... for our membrane process testing equipment, and correspondingly, a ... membranes,” explains Sterlitech President Mark Spatz. “The addition ...
Breaking Biology Technology:Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2
... to support regulatory filings for S0812 and additional ... Senomyx, Inc. (Nasdaq: SNMX ), ... to discover and develop novel flavor ingredients for ... today that it has initiated development activities for ...
... 9 /PRNewswire-Asia-FirstCall/ -- Yongye Biotechnology,International, Inc. (OTC Bulletin ... producer and distributor of nutrients for plants and,animals, ... announced that the,Company,s management will present at the ... Dana Point, California. , ...
... Shire plc (LSE: SHP, NASDAQ: SHPGY ), ... Barr Laboratories, Inc.,("Barr) and Mylan, Inc. ("Mylan) dated 2 ... the filing of an Abbreviated New Drug Application,("ANDA") for ... carbonate). , FOSRENOL is protected ...
Cached Biology Technology:SENOMYX ANNOUNCES INITIATION OF DEVELOPMENT ACTIVITIES FOR NEW BITTER BLOCKERS 2SENOMYX ANNOUNCES INITIATION OF DEVELOPMENT ACTIVITIES FOR NEW BITTER BLOCKERS 3SENOMYX ANNOUNCES INITIATION OF DEVELOPMENT ACTIVITIES FOR NEW BITTER BLOCKERS 4Yongye Biotechnology to Present at Roth Conference 2Yongye Biotechnology to Present at Roth Conference 3Shire Receives FOSRENOL Paragraph IV Notice Letters from Barr Laboratories and Mylan 2
Human RXR beta/NR2B2 MAb (Clone H7341) Keywords: RXRbeta, RXRbeta, Retinoid X Receptor beta...
PSMD1 Antibody...
Terrific Broth, 1 kg. Mixture of casein peptone, yeast extract, K2HPO4, and KH2PO4.Used at 47 g/l for E. coli growth with higher cell densities. Category: Nucleotides & Enzymes & Biochemicals, Ultrap...
... 1200L sets the new standard for ... incorporating the latest technologies and providing ... analytical needs. The Atmospheric Pressure ... Quadrupole Analyzer provide superior selectivity and ...
Biology Products: