Navigation Links
Diabetes risk in children increases risk for weak bones
Date:8/16/2010

AUGUSTA, Ga. Children at risk for diabetes before they reach puberty also appear to be at risk for weak bones, Medical College of Georgia researchers report.

A study of 140 overweight children age 7-11 who got little regular exercise found that the 30 percent with signs of poor blood sugar regulation had 4-5 percent less bone mass, a measure of bone strength, said Dr. Norman Pollock, bone biologist at MCG's Georgia Prevention Institute.

The study is the first to suggest the association between weaker bones and type 2 diabetes risk in children. Type 2, which is becoming more common in children, is often associated with obesity and inactivity; type 1 diabetes, believed to result from genes and environmental triggers, is known to be associated with poor bone health.

"This finding provides the first clue linking childhood obesity to skeletal fractures," said Pollock, first author on the study published in the Journal of Bone and Mineral Research. "While overweight children may have more bone mass than normal-weight kids, it may not be big or strong enough to compensate for their larger size."

It's not as simple as saying that everyone who is overweight has weak bones, he notes. It may have more to do with how fat is distributed throughout the body. For instance pre-diabetics tend to have more fat around their abdominal area, specifically visceral fat, a type of fat deep in the belly that is linked to diabetes and cardiovascular disease.

In this study, higher amounts of visceral fat were associated with lower bone mass while more body fat overall was associated with higher bone mass. "Taken together, it seems that excessive abdominal fat may play a key role linking pre-diabetes to lower bone mass," Pollock said.

The findings appear to be another wakeup call for parents about the potential lifelong consequences of an overweight childhood. And increased physical activity might be a relatively simple fix.

"Our greatest window of opportunity to enhance bone strength and ultimately reduce the risk of osteoporosis is during childhood, before the capacity to build bone diminishes," Pollock said. "One of the best things you can do for bone development and general health is exercise."

"Children have a lot of potential and a whole lot of time to make positive changes," echoed Dr. Catherine Davis, clinical health psychologist at the Georgia Prevention Institute and study co-author whose research has shown that regular physical activity reduces children's body fat and diabetes risk and even improves learning. "If you could patent exercise as a drug, somebody would be really, really rich."

Next steps include learning more about how abdominal fat impairs bone mass, including looking at the activity of cells that make and destroy bone the bone makers should be more active in children as well as vitamin D and vitamin K metabolism.


'/>"/>

Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
Source:Eurekalert  

Related biology news :

1. JDRF funded study links hygiene hypothesis to diabetes prevention
2. Researchers continue to find genes for type 1 diabetes
3. Scientists from Granada find a potential treatment to prevent diabetes and obesity
4. Diabetes researcher gets $5M boost
5. Green tea may delay onset of type 1 diabetes
6. Moderate use averts failure of type 2 diabetes drugs in animal model
7. Geisinger research: Antimalarial drug prevents diabetes in arthritis patients
8. Bayhill Therapeutics and the Juvenile Diabetes Research Foundation announce research collaboration
9. A new weapon in the fight against obesity and diabetes
10. Coping and copulation behavior may help calculate diabetes risk
11. JDRF funded research shows promise for prevention, reversal of type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Diabetes risk in children increases risk for weak bones
(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
(Date:4/5/2017)... -- KEY FINDINGS The global market for ... of 25.76% during the forecast period of 2017-2025. The ... the growth of the stem cell market. ... INSIGHTS The global stem cell market is segmented on ... stem cell market of the product is segmented into ...
(Date:4/3/2017)... , April 3, 2017  Data captured ... engineering platform, detected a statistically significant association ... prior to treatment and objective response of ... potential to predict whether cancer patients will ... treatment, as well as to improve both pre-infusion ...
Breaking Biology News(10 mins):
(Date:8/10/2017)... PA (PRWEB) , ... August 09, 2017 , ... ... to the classroom next week-- as students. From August 14th through the 16th, ... The institute, which debuted in the summer of 2016, provides Philadelphia-based middle school ...
(Date:8/10/2017)... ... , ... Each year in the United States more than 300,000 people are ... lifestyle and, even worse, the one-year mortality rate is high, ranging from 12 percent ... California Davis Medical Center (Sacramento) and Second Xiangya Hospital of the Central-South University (Hunan, ...
(Date:8/10/2017)... SAN DIEGO, California, USA (PRWEB) , ... August ... ... and photonics, has partnered with four international biomedical optics laboratories — the Wellman ... Massachusetts General Hospital, Medical Laser Center Lübeck and the Beckman Laser Institute at ...
(Date:8/10/2017)... ... August 10, 2017 , ... SPIE, the international ... as its exclusive sales representative for SPIE Journals in Japan. Kinokuniya has a ... Library in Japan. , “We look forward to expanding our relationship with Kinokuniya ...
Breaking Biology Technology: