Navigation Links
Diabetes researcher gets $5M boost

A respected Queensland University of Technology researcher and his team have received $5 million from the Juvenile Diabetes Foundation International, the third-biggest grant they have ever given to an Australian research team.

Professor Nathan Efron of QUT's Institute of Health and Biomedical Innovation is the principal researcher of the five year study, which will test the efficacy of detecting the progress of diabetic neuropathy by looking at the nerves in the cornea, at the front of the eye.

Diabetic neuropathy is a condition affecting around 50 per cent of diabetic patients at varying degrees of severity, which causes the degeneration of nerves, mostly in the arms and leg.

Professor Efron has found that the nerves affected by neuropathy are an exact match to nerves found in front of the eye, and this study will test whether looking at their level of degeneration in these nerves over a period of time would match the nerve degeneration found in arms and legs.

"We want to see how well the degeneration of the nerves in the cornea matches the degeneration of nerves throughout the body, and if it matches it will mean that we can monitor diabetic neuropathy using a simple eye test," Professor Efron said.

"Over the next five years, we have 400 patients with diabetes who we will be testing on two sites - here at QUT and at the University of Manchester in England - who will receive this test, called corneal confocal microscopy, to see the value in tracking the condition in this way."

Diabetic neuropathy is currently measured by taking a skin biopsy from the foot, and running tests which could take up to three days, whereas the quick and non-invasive eye tests would see results in a matter of minutes.

Professor Efron said there were multiple benefits of being able to measure the onset of neuropathy, one being that there were drugs in development which aim to cure diabetic neuropathy.

"When these drugs are ready to come onto the market, we will, using our method, be able to detect nerve degeneration early and then hopefully cure it," he said.

For the tests, patients would receive a drop of anaesthetic in the eye, then a corneal confocal microscope would capture a 20 second "movie" of their eye for analysis.

There are also three more tests being looked at - the first, called non-contact corneal aesthesiometry, measures how nerve degeneration is affecting the function of the cornea, by projecting tiny puffs of air into the eye, growing progressively stronger until the patient can feel it.

Two more eye tests will look at the effect of nerve degeneration on the retina.

"Diabetic patients currently go for yearly eye tests anyway, so we are saying that these tests could be done at the same time, and only take a few minutes," Professor Efron said.


Contact: Sharon Thompson
Queensland University of Technology

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Gender, coupled with diabetes, affects vascular disease development
3. Breakthrough research identifies how cells from pigs may cure diabetes
4. Botched production of insulin molecule may lead to diabetes
5. Joslin researchers uncover potential role of leptin in diabetes
6. Insulins brain impact links drugs and diabetes
7. Exercise improves thinking, reduces diabetes risk in overweight children
8. UVa Health System team uncovers genes role in type 1 diabetes
9. Childrens Hospital studying drug with the potential to prevent/delay onset of type 1 diabetes
10. JDRF awards University of Copenhagen professor with grant to conduct innovative diabetes research
11. Cancer and arthritis therapy may be promising treatment for diabetes
Post Your Comments:
(Date:10/26/2015)...  Delta ID Inc., a company focused on bringing ... devices, announced its ActiveIRIS® technology powers the iris recognition ... by NTT DOCOMO, INC in Japan ... to include iris recognition technology, after a very successful ... May 2015, world,s first smartphone to have this capability. ...
(Date:10/23/2015)... and GOLETA, California , ... HFES conference, BIOPAC and SensoMotoric Instruments (SMI) announce a ... eye tracking data captured during interactive real-world tasks ... and play integration of their established wearable solutions for ... to synchronize gaze behavior captured with SMI Eye ...
(Date:10/22/2015)... SAN JOSE, Calif., Oct. 22, 2015  Synaptics (NASDAQ: SYNA ... results for its first quarter ended September 30, 2015. ... first quarter of fiscal 2016 grew 66 percent over the comparable ... quarter of fiscal 2016 was $23.8 million, or $0.62 per diluted ... net income for the first quarter of fiscal 2016 grew 39 ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... --> ... 2020 report analyzes that automating biobanking workflow will ... long-term samples, minimizing manual errors, improving the workflow ... errors such as mislabeling or inaccurate sample barcoding ... a vital role in blood fractionation, DNA extraction, ...
(Date:11/25/2015)... , Nov. 25, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... , President and CEO of Neurocrine Biosciences, will be ... in New York . ... the website approximately 5 minutes prior to the presentation ... of the presentation will be available on the website ...
(Date:11/25/2015)... ... 25, 2015 , ... Jessica Richman and Zachary Apte, founders ... initial angel funding process. Now, they are paying it forward to other microbiome ... investments in the microbiome space. In this, they join other successful entrepreneurs-turned-angels ...
(Date:11/24/2015)... Nov. 24, 2015 /CNW/ - iCo Therapeutics ("iCo" or ... financial results for the quarter ended September 30, ... Canadian dollars and presented under International Financial Reporting ... ," said Andrew Rae , President ... iCo-008 are not only value enriching for this ...
Breaking Biology Technology: