(Santa Barbara, Calif.) Two new groundbreaking scientific papers by researchers at UC Santa Barbara demonstrate the synthesis of nanosize biological particles with the potential to fight cancer and other illnesses. The studies introduce new approaches that are considered "green" nanobiotechnology because they use no artificial compounds.
Luc Jaeger, associate professor of chemistry and biochemistry at UCSB, explained that there is nothing short of a revolution going on in his field one that permeates all areas of biochemistry, especially his area of nanobiotechnology. The revolution involves understanding the role of RNA in cells.
"Considering the fact that up to 90 percent of the human genome is transcribed into RNA, it becomes clear that RNA is one of the most important biopolymers on which life is based," said Jaeger. "We are still far from understanding all the tremendous implications of RNA in living cells."
Jaeger's team is putting together complex three-dimensional RNA molecules nanosize polyhedrons that could be used to fight disease. The molecules self assemble into the new shapes. The work is funded by the National Institutes of Health (NIH), and there is a patent pending jointly between NIH and UCSB on the new designs.
"We are interested in using RNA assemblies to deliver silencing RNAs and therapeutic RNA aptamers to target cancer and other diseases," said Jaeger. "It is clear that RNA is involved in a huge number of key processes that are related to health issues."
Jaeger believes the RNA-based approaches to delivering new therapies in the body will be safer than those using artificial compounds that might have undesirable side effects down the line.
"By using RNA molecules as our primary medium, we are practicing 'green' nanobiotechnology," explained Jaeger. "The research program developed in my lab at UCSB aims at contributing in a positive way to medicine and synthetic biology. We
'/>"/>
| Contact: Gail Gallessich gail.g@ia.ucsb.edu 805-893-7220 University of California - Santa Barbara Source:Eurekalert |
Related biology news :
1. Bovine genome provides clues to possible new developments
2. New developments in reproductive medicine
3. ACS webinar features developments in online water and wastewater monitoring
4. Conference to discuss sensing technology developments and opportunities
5. Deep biosphere research points to new methods for recovering petroleum
6. Human protein atlas will help pinpoint disease
7. Duke study pinpoints potential green collar job growth in US
8. Leeds research points to new therapy for hepatitis C treatment
9. First-ever socioeconomic study on coral reefs points to challenges of coastal resource management
10. Study first to pinpoint why analgesic drugs may be less potent in females than in males
11. Studies point to novel target for treating arrhythmias
 |
| Copyright © 2003-2012 Bio-Medicine. All rights reserved. ABOUT | CONTACT US | DISCLAIMER | PRIVACY POLICY | TERMS AND CONDITIONS |  |