Navigation Links
Developmental gene-environment interactions: A model for psychosis

2009; Dominguez et al., 2009). According to the model of psychosis proneness persistence impairment, genetic background factors impact on a broadly distributed and transitory population expression of psychosis during development. Hence, poor prognosis, in terms of persistence and clinical need, can be predicted by environmental exposure interacting with genetic risk.

Environmental risk factors

According to findings from epidemiological research, rates of schizophrenia and related psychotic disorders are substantially influenced by a spectrum of environmental risk factors with significant impact on children and adolescents growing up in European societies.

  • Urbanicity
    Growing up in an urban area has been shown to be associated with an increased risk of developing psychotic disorder in later life (Spauwen et al., 2004). For children growing up in big cities a more than twofold risk compared to children in rural environments has been shown, independent of other risk factors. According to latest research findings up to 25% of all schizophrenia cases can be attributed to this effect.

  • Migration
    Migration presents an increasing challenge to European countries. In immigrant populations the risk of developing psychotic disorders is much higher compared to the risk in both the host country and the country of origin. These findings point to a significant impact associated with the often problematic social interaction between migrants and majority populations.

  • Cannabis use
    Apart from alcohol, cannabis is the most widely used drug in Europe. Although its effects were considered to be harmless compared to other drugs until recently, many studies have shown that cannabis use, in particular heavy use during adolescence, increases the risk of psychotic disorders such as schizophrenia.

  • Childhood victimisation
    In European countries at least 15% of populations are the victims of s

Contact: Sonja Mak
European College of Neuropsychopharmacology

Page: 1 2 3 4 5 6

Related biology news :

1. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
2. Carnegies Donald Brown receives lifetime achievement award from Society for Developmental Biology
3. Mouse model provides a new tool for investigators of human developmental disorder
4. Specific genetic cause of fetal alcohol-related developmental disorders found
5. Genetic marker linked to problem behaviors in adults with developmental disabilities
6. Developmental delay could stem from nicotinic receptor deletion
7. Chinese scientists discover marker indicating the developmental potential of stem cells
8. Tufts wins NCRR grant for Collaborative Cluster in Genome Structure and Developmental Patterning
9. Developmental problems: Some exist in the genes
10. Fertilizer chemicals linked to animal developmental woes
11. Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue
Post Your Comments:
(Date:9/26/2015)... -- Results of a TactioRPM pilot project in a ... Stanford Medicine X Conference. In a presentation titled ... Devices and Pharmacogenomics", Roger Simard , Pharmacist ... senior patients equipped with connected health devices and ... TactioRPM remote patient monitoring platform were empowered to ...
(Date:9/10/2015)... , Sept. 10, 2015 This report ... wearable technology products today, and emerging sensor types that ... risen through the peak of the wearable technology hype ... slide to disillusionment. The common feature with all of ... key enabler for their most useful functions. Sensors collect ...
(Date:9/10/2015)... 2015 Pursuant Health has collaborated with ... an interactive, image-based health risk assessment (HRA) optimized ... The unique assessment quantifies user results into an ... an individual,s biological age based on personal health ... the kiosk. Comprised of age, gender, ...
Breaking Biology News(10 mins):
... of the brain, which scavenge pathogens and damaged neurons, are ... research by Duke neuroscientists. Earlier studies by Staci Bilbo, ... laboratory rats experiencing an infection at an early age have ... their learning and memory. In a study published ...
... Lake City Physicians preparing to deliver a baby look ... whether or not to perform a C- section. But a ... shows that those heart rate patterns may not be a ... lead to unnecessary interventions and higher costs. "We,re trying ...
... a class of theoretical concepts for manipulating the climate ... caused by greenhouse gasses. But its potential effectiveness and ... could help narrow these uncertainties. A team composed of ... and Harvard,s David Keith used modeling to determine the ...
Cached Biology News:
(Date:10/9/2015)... ... ... Leading microbial genomics startup uBiome today launched the first-ever microbiome app, in ... and the microbiome. The study uses the ResearchKit framework, designed by Apple, to gather ... uBiome app is available as a free download from the App Store. The first ...
(Date:10/8/2015)... , Oct. 8, 2015  ATCC, the premier ... that it has been selected by The Michael J. ... cell lines to academic, pharmaceutical, and biotechnology organizations committed ... the United States , and more ... the United States , and more ...
(Date:10/8/2015)... Oct. 8, 2015 The 2015 Nobel Prize in ... of Texas at Dallas. Aziz Sancar , who earned ... Dallas in 1977, is one of three scientists who ... monitor and repair damaged DNA on a molecular level.  --> ... cell biology from UT Dallas in 1977, ...
(Date:10/8/2015)... , Oct. 8, 2015  Sigma-Aldrich Corporation (NASDAQ: ... ® brand within its Applied Diagnostics and ... acid reference standards product line with ten certified ... tested bile acids and their stable-labeled internal standards. ... of lithocholic acid, taurocholic acid and native and ...
Breaking Biology Technology:
... 1 ChromaDex, Inc. ("ChromaDex"),today announced that effective ... Acquisition, Inc. ("CDI"), the wholly-owned subsidiary of Cody,Resources, ... ChromaDex to be wholly owned by a company ... be better positioned to meet the ongoing needs,of ...
... Will Support Development of Bavituximab and Fully Human ... ... Peregrine,Pharmaceuticals, Inc. (Nasdaq: PPHM ), a clinical stage ... C virus (HCV) infection, today announced it has entered into ...
... July 1 Isis,Pharmaceuticals, Inc. (Nasdaq: ISIS ... $20 million in Ibis Biosciences, Inc., an Isis,subsidiary. ... the Ibis,T5000(TM) Biosensor System, which offers a unique ... By making this,investment, Abbott retains the exclusive option ...
Cached Biology Technology:
... for 25 chips provides the chips and ... (at picogram levels) with the Experion automated ... HighSens microfluidic chips, 2 x 1,250 microliters ... HighSens stain, 20 microliters RNA ladder, 2 ...
Vitronectin Immunogen: Purified, full length, native human protein. Storage: -20 C, Avoid Freeze/Thaw Cycles...
... StdSens analysis kit for 25 chips provides ... standard-sensitivity RNA analysis (at nanogram levels) with ... includes 25 RNA StdSens microfluidic chips, 2 ... 20 microliters RNA StdSens stain, 2 x ...
... White solid. PROTECT FROM LIGHT. PACKAGED UNDER ... pyrimidinone compound that acts as a potent ... (IC 50 = 200 nM and ... with little activity against the dehydrogenase activity ...
Biology Products: