Navigation Links
Development of new anti-cancer gene therapy approach using lentiviral vectors
Date:3/29/2010

Neuherberg, March 29, 2010. Helmholtz Zentrum Mnchen has launched a new cooperative project with SIRION BIOTECH GmbH in Martinsried to develop new therapeutic approaches against lymphoid tumors. With a two-year grant from the Federal Ministry for Economics and Technology, the two partners will seek to further develop lentiviral vector systems to better understand the disease mechanisms of this cancer form and to devise approaches for treatment.

The future of gene therapy approaches in cancer treatment is especially dependent on the quality of the vectors involved in the regulation of gene expression in the tumor cells. Lentiviruses are a very promising vector system for this they even reach difficult-to-access cell types such as the hematopoietic cells of the blood-forming system.

With their new research cooperation Helmholtz Zentrum Mnchen and SIRION BIOTECH seek to optimize the use of lentiviruses as gene vectors for hematopoietic cells. Over the long term this may result in an important step forward in the therapy of malignant lymphomas. The Federal Ministry for Economics and Technology is funding the project over the next two years with approximately 500,000 euros.

"We quite consciously decided on a cooperation partner from the biotech sector," said Professor Gnther Wess, scientific-technical director of Helmholtz Zentrum Mnchen. "The symbiosis of our scientific expertise in the field of lentiviruses with the technical know-how of SIRION BIOTECH promises to yield valuable insights about the molecular disease mechanisms and the function of disease-relevant genes in the blood cells."

Dr. Nataa Anastasov, who is in charge of the project at the Institute of Radiation Biology of Helmholtz Zentrum Mnchen, and her colleagues from SIRION BIOTECH already have concrete ideas regarding the new generation of lentiviruses: "We want to specifically refine the lentiviral vectors to target the tumor cell markers." To achieve this, the r
'/>"/>

Contact: Sven Winkler
presse@helmholtz-muenchen.de
49-898-931-873-946
Helmholtz Zentrum Mnchen - German Research Center for Environmental Health
Source:Eurekalert

Page: 1 2

Related biology news :

1. Compound screening for drug development made simpler
2. Quickly and easily integrate fingerprint biometric features into portable applications with Texas Instruments comprehensive, low cost fingerprint development kit
3. Chemists influence stem-cell development with geometry
4. Opposing functions of a key molecule in the development of organisms
5. Development of more muscular trout could boost commercial aquaculture
6. Sonic hedgehog gene found in an unexpected place during limb development
7. Model may offer better understanding of embryonic development
8. Chemical competition: Research identifies new mechanism regulating embryonic development
9. ACS webinar features developments in online water and wastewater monitoring
10. Rondaxe and TD2 form strategic drug development alliance
11. Zebrafish swim into drug development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Researchers in France have hit on a novel ... receive the correct and most effective treatment possible., ... the western and developing world. If left untreated, ... to renal failure and other complications. In many ... problem. Clearly a more effective pathological approach to ...
(Date:4/17/2014)... Indiana University researchers have detected new early-warning signs of ... discovery could have far-reaching implications for the diagnosis and ... over 25 million Americans. , "We had not expected ... such early stages," said Ann Elsner, professor and associate ... author of the study. "We set out to study ...
(Date:4/17/2014)... have uncovered a new way the immune system may ... efforts to use immune cells to treat illness. , ... the immunological equivalent of "neighborhood police" specialized squads ... organ, instead of an entire city, the body. , ... Louis have shown that the liver, skin and uterus ...
Breaking Biology News(10 mins):New technique detects microscopic diabetes-related eye damage 2New technique detects microscopic diabetes-related eye damage 3Some immune cells defend only 1 organ 2
... Barbara, CA The Bren School-based authors of a study ... have observed toxicity to marine organisms resulting from exposure to ... toxic under similar conditions. Lead author and assistant research ... both Bren School professors and lead scientists at the ...
... at the University of California, Riverside discovered a tiny fairyfly wasp ... United States until then. Nearly exactly a year later, he ... is well established in the country. Called Gonatocerus ater ... North America from Europe. It lays its eggs inside the ...
... New Rochelle, NY, January 24, 2012The time for commercial development ... and curable with gene therapy deserve access to the technology, ... Wilson, MD, PhD, Editor-in-Chief of Human Gene Therapy ... . Human Gene Therapy and Human Gene ...
Cached Biology News:Nano form of titanium dioxide can be toxic to marine organisms 2Wasp found in upstate New York shows up in Southern California 2Gene therapy is a 'disruptive science' ready for commercial development 2
(Date:1/15/2014)... 2014 AudioNotch is the internet's leading ... the treatment of tinnitus. Patients listen to sound therapy ... a period of weeks to months, their tinnitus volume decreases. ... forms: Notched Music and Notched White Noise. Now, AudioNotch is ...
(Date:1/14/2014)... 2014 Carahsoft and CDS Federal Services ... 2014 at 2pm EST (11am PST), “Natural Language Processing: ... on how technology can turn raw, heterogeneous data into ... agencies. The online webinar will last approximately one hour. ...
(Date:1/14/2014)... BURLINGAME, Calif. , Jan. 14, 2014 As pet owners ... no doubt many of them wrote: "Take better care of my ... and even designer clothes and top-brand carrying cases to take the ... Pet parents might also feel compelled to buy some pricey toys ...
(Date:1/14/2014)... and BETHESDA, Md. , Jan. 14, ... with two institutes from the National Institutes of Health ... bringing safer, more effective treatments to patients on a ... for Advancing Translational Sciences (NCATS) and the National Eye ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3
... Germany will present itself as one of the,world,s ... BIO,International Convention. Under the "Breakthroughs in Regenerative Medicines,in ... into the,latest research results in the area of ... the regulatory framework conditions will be,introduced in a ...
... Corporation (Nasdaq: MATK ) announced that it intends ... 2009 on June 3, 2009, at approximately 4:00 p.m. Eastern ... Martek will conduct a conference call to discuss these results ... call live via webcast by visiting Martek,s web site at ...
... North Carolina And ChinaRESEARCH TRIANGLE PARK, N.C., May ... Health Sciences has signed an agreement with China ... Institute for International Drug Development. Building on strengths ... development, and education, the Institute will help to ...
Cached Biology Technology:BIO International Convention 2009: Research Location Germany Presents Potential in Regenerative Medicine 2The Hamner Institutes Announce Partnership With China Medical City 2The Hamner Institutes Announce Partnership With China Medical City 3