Navigation Links
Developing a tool for identification -- even using very degraded DNA samples
Date:4/12/2011

Frequently the only biological material available to identify persons or find next of kin is DNA in a very degraded state. In these cases, the kits usually employed to carry out DNA identifications do not produce very positive results, given that all the DNA is not available, and that which is available is highly fragmented. Biochemist Adrian Odriozola has developed a tool for identifying persons from these small fragments of DNA. His thesis, presented at the University of the Basque Country (UPV/EHU), is entitled Developing molecular tools for analysis of highly degraded DNA samples.

In order to develop this tool, Dr Odriozola used sequences known as STR (short tandem repeat). These are sequences of small fragments of DNA that are continuously repeated and turn out to be highly useful for distinguishing between persons, due to the fact that the number of repetitions of the sequence varies according to the individual. Precisely, the kits that Odriozola investigated and that are currently employed in Forensic Genetics are based on STR analysis. However, they fail when the DNA is degraded, and so the researcher drew up a new route for analysing STRs, taking these conditions into account. Thanks to this line of research, Dr Odriozola has been able to publish a number of articles together with research colleagues at the UPV/EHU, in publications such as the International Journal of Legal Medicine. The University has also been granted two patents.

Working with shorter sequences

To carry out identification using DNA, it is first of all essential to undertake millions of copies of the fragment to be analysed (a process called amplification); in this case, of the STRs, which are obtained using the PCR (polymerase chain reaction) technique. So that PCR can function, primers have to adhere themselves to the two ends of each of the STR sequences. In this way, on undertaking PCR, copies are obtained of both the STR sequ
'/>"/>

Contact: Amaia Portugal
a.portugal@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Repair in the developing heart
2. Space researchers developing tool to help disoriented pilots
3. Carnegie Mellon developing automated systems to enable precision farming of apples, oranges
4. Scientists developing food allergy treatment
5. Pigs and dogs can bridge gap between mice and humans in developing new therapies
6. Nutrigenomics -- developing personalized diets for disease prevention
7. Researchers examine developing hearts in chickens to find solutions for human heart abnormalities
8. Preventing rangeland erosion: Developing better management practices in Iran
9. Veterinarians developing model to help producers, vets make cattle more comfortable
10. Iowa State researchers developing clean, renewable energy for ethanol industry
11. Nutrigenomics -- developing personalized diets for disease prevention -- part 2 just published in OMICS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/10/2015)... Germany , August 10, 2015 ... leader in Eye Tracking Technology for more than two ... Tracking Platform for integration into all consumer display formats. ... for seamless integration of eye tracking into consumer tablets, ... augmented reality smart glasses. Omnivision,s leading sensor technology contributes ...
(Date:8/5/2015)... According to a new market ... Services, Vertical (BFSI, Airport, IT & Telecom, Utilities, Education, ... to 2020", published by MarketsandMarkets, defines and segments the ... segments. The global PIAM Market is estimated to grow ... 2019, at a CAGR of 14.9 % from 2014 ...
(Date:8/3/2015)... , Aug. 3, 2015 Synaptics, Inc. ... interface solutions, today announced that members of the executive ... the Pacific Crest Global Technology Leadership Forum on Tuesday, ... conference will be held at the Sonnenalp Resort in ... The presentation may include forward-looking information. An audio webcast ...
Breaking Biology News(10 mins):SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4
... , April 17, 2013 /PRNewswire-iReach/ -- 2013  Infectious ... of Department of Defense (DoD) clinical and research ... challenges facing the military, revealed that it is ... conduct a completely paperless clinical study resulting in ...
... Institute for Natural Resources, (INR) Oregon Biodiversity Information ... last night at the NatureServe network,s annual Biodiversity ... recognizes ORBIC,s leadership in engaging network members in ... ORBIC is one of three members of the ...
... Heritage Program (NCNHP) received the 2013 Scientific and Technical ... Biodiversity Without Boundaries conference in Baltimore. , "This ... achievement of the North Carolina Natural Heritage Program in ... and CEO of NatureServe. "This is the second part ...
Cached Biology News:Federal Government Organization achieves cleaner and faster Clinical Study Data using Tablet PCs from TabletKiosk 2Oregon Biodiversity Information Center wins 2013 Natureserve Network Collaboration Award 2North Carolina Natural Heritage Program earns 2013 Award for Science and Technical Achievement 2
(Date:8/27/2015)... , Aug. 27, 2015 In ... by FedEx, UPS and The US Postal Service ... specimens classified as ,select agents, by the CDC, ... of handling these sensitive shipments. Marken ... transportation regulations, trained and certified personnel to ensure ...
(Date:8/26/2015)... 26, 2015 /PRNewswire/ - iCo Therapeutics ("iCo" or "the ... results for the quarter ended June 30, 2015. ... dollars and presented under International Financial Reporting Standards ... respect to our Oral Amp B program, rapidly ... said Andrew Rae , President & CEO ...
(Date:8/26/2015)... , Aug. 26, 2015  The Diabetes Research ... University of Miami Miller School of Medicine, announced ... trial to test for the first time a ... completed.  This FDA approved Phase I/II study builds ... and is an important first step toward the ...
(Date:8/26/2015)... , August 26, 2015 Israel Proves Its ... wins 1 st place  Wayerz comes in 5 ... Israel by venture capital fund JVP, with Chinese ... US, China , Israel , ... .  Impressive achievement for the Israeli representatives in the ...
Breaking Biology Technology:Marken Ensures Safe Transportation Of Select Agents And Toxins 2iCo Therapeutics Announces Second Quarter 2015 Financial Results 2iCo Therapeutics Announces Second Quarter 2015 Financial Results 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 2Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 4Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 2Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 3Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 4Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 5Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 6
... Green Mountain Energy Company to take the necessary steps in ... enabling them to operate as a "carbon neutral" analytical laboratory. ... ... Alkemists Pharmaceuticals today announced that it has partnered with Green Mountain ...
... 30 , - Shares Acquired From Biggar ... biotechnology company,focused on eye disease, vascular disease and ... based in Belgium have together acquired an 8%,stake ... Biggar Limited, a,charitable foundation that is ThromboGenics largest ...
... SAN DIEGO, July 29 Arena Pharmaceuticals,Inc. (Nasdaq: ... second quarter 2008,financial results after the NASDAQ Global ... afternoon, Jack Lief, Arena,s President and Chief,Executive Officer, ... Chief Financial Officer, will host a conference call ...
Cached Biology Technology:Alkemists Sets The Bar, Becoming a 'Green' Analytical Laboratory 2Alkemists Sets The Bar, Becoming a 'Green' Analytical Laboratory 3ThromboGenics Announces Private Investors Acquire 8% Stake in the Company 2ThromboGenics Announces Private Investors Acquire 8% Stake in the Company 3Arena Pharmaceuticals to Report Second Quarter 2008 Financial Results and to Host Conference Call and Webcast on Tuesday, August 5, 2008 2Arena Pharmaceuticals to Report Second Quarter 2008 Financial Results and to Host Conference Call and Webcast on Tuesday, August 5, 2008 3
Proline-serine-threonine phosphatase-interacting protein 2...
E2F2 protein...
Anti-gamma Glutamyl Transferase (gammaGT) Host: mouse monoclonal Species Reactivity: human Applications: WB, IP, FC Storage: 4C...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Biology Products: