Navigation Links
Detecting mirror molecules
Date:5/22/2013

Harvard physicists have developed a novel technique that can detect molecular variants in chemical mixtures greatly simplifying a process that is one of the most important, though time-consuming, processes in analytical chemistry.

As described in a paper in Nature, post-doctoral researcher David Patterson, Professor of Physics John Doyle and Dr. Melanie Schnell of the Center for Free-Electron Laser Science (CFEL) in Hamburg, Germany developed a system that relies on finely-tuned microwave fields to identify molecular variants apart, and to determine how much variant is in a mixture.

The ability to tell such variants apart, researchers said, is critical because many chemical compounds exist in two forms, each of which is a mirror image of the other. Such molecules are called chiral, from the ancient Greek for hand, and are often described as being either "right-handed" or "left-handed."

Knowing whether a molecule is right- or left-handed, scientists say, is important, because each type of molecule behaves differently in chemical reactions. Much of biology, for example, is predicated on the idea that amino acids are "left-handed," while sugar molecules are "right-handed."

"The 'wrong' sort of a compound can function completely differently in an organism," explains Schnell, who leads an independent Max Planck research group for structure and dynamics of molecules at CFEL. "In the best case it is just ineffective. In the worst case it is toxic."

The challenge, however, is that telling the two variants of a chiral molecule apart is no easy job.

A common way to discern between them is to shine linear polarised light through them. While one variant will turn the plane of polarisation to the left, the other will turn it to the right. The problem with that method, researchers say, is that it produces rather weak effects, and can only be used on liquid samples, and it can be difficult to use on samples th
'/>"/>

Contact: Peter Reuell
preuell@fas.harvard.edu
617-496-8070
Harvard University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Detecting breast cancers fingerprint in a droplet of blood
2. By detecting smallest virus, researchers open possibilities for early disease detection
3. Texas Biomed reports faster, more economical method for detecting bioterror threats
4. Holding a mirror to brain changes in autism
5. Iowa State, Ames Lab researchers invent new tool to study single biological molecules
6. New model gives hands-on help for learning the secrets of molecules
7. Weighing molecules 1 at a time
8. Nano-velcro clasps heavy metal molecules in its grips
9. Researchers develop new stamping process to pattern biomolecules at high resolution
10. A class of RNA molecules protects germ cells from damage, Penn vet researchers show
11. Dance of water molecules turns fire-colored beetles into antifreeze artists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2015)... PRINCETON, N.J. , Aug. 18, 2015 ... be a key contributor to the Submission ... hosted by IRISS, a non-profit forum. Dedicated to ... IRISS provides a neutral platform for industry, ... to share information and work towards a ...
(Date:8/12/2015)... Aug. 12, 2015   MedNet Solutions , an ... spectrum of clinical research, is proud to announce that ... comprehensive SaaS-based eClinical technology platform, has led the way ... two quarters of 2015.   Q2 2015 and Q1 ... measured by contract value sold in the company,s 15 ...
(Date:8/12/2015)... Aug. 12, 2015  Synaptics Inc. (NASDAQ: ... solutions, today announced that four of its fingerprint ... have officially been named FIDO Certified™ by the ... the certification, Synaptics, Natural ID™ fingerprint solutions are ... Framework (UAF) standard and are interoperable among other ...
Breaking Biology News(10 mins):Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3MedNet Solutions Experiences Explosive Corporate Growth 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3
... , June 4, 2013  With invasions of computer systems ... Identify Security Software Inc. ( www.identifyss.com ) today announced ... http://photos.prnewswire.com/prnh/20130604/FL25436LOGO ) "Identify Security Software ... way for businesses and institutions to manage and control ...
... and NEW ORLEANS , June 3, 2013 ... Microsoft demonstrates an FPC fingerprint touch sensor in combination with a ... demonstrations showcase a number of innovative online use cases using FPC,s ... to sign on to their Microsoft account, make online payments and ...
... the Duke-NUS Graduate Medical School (Duke-NUS) in Singapore has ... protein linked to stem cell-like behavior in terminal-stage chronic ... that may extend the survival of these patients. ... Proceedings of the National Academy of Sciences , is ...
Cached Biology News:Identify Security Software to Make Cyberspace Secure 'Once And For All' 2Identify Security Software to Make Cyberspace Secure 'Once And For All' 3Fingerprint Cards (FPC) Demonstrates Fingerprint Biometric Touch Sensor for Microsoft Windows 8.1 2Singapore research team identifies new drug target in deadly form of leukemia 2
(Date:8/31/2015)... Israel , Aug. 31, 2015 ... Dario™ Diabetes Management Solution, today announced it recently ... million. Funds will be used to support the ... the Dario, a mobile, cloud-based, diabetes management solution ... stylish, ,all-in-one, pocket-sized, blood glucose monitoring device, and ...
(Date:8/31/2015)... ... August 31, 2015 , ... There’s a new treatment option ... the first commercially available new FDA approved system in the last 14 years, and ... the high Amenorrhea (zero bleeding) rate of 66%, the high Patient Satisfaction rate of ...
(Date:8/28/2015)... 2015 According to a new ... Storage Systems, Thawing Equipment, Alarms), by Biospecimen (Human Tissue, ... End User - Global Forecast to 2020", published by ... USD 3,731.03 Million by 2020 from USD 2,150.48 Million ... 2015 and 2020. Browse 74 Tables ...
(Date:8/28/2015)... ... 2015 , ... Riordan-McKenna Institute founders, stem cell ... the use of sterile, dehydrated amniotic tissue AlphaPATCH™ developed by Amniotic Therapies ... knee wound. , The case involved a 78-year-old male, who presented with a ...
Breaking Biology Technology:LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 2LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 3LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 4U.S. FDA Approves Minerva Endometrial Ablation System 2U.S. FDA Approves Minerva Endometrial Ablation System 3Biopreservation Market Worth 3,731.03 Million USD by 2020 2Biopreservation Market Worth 3,731.03 Million USD by 2020 3Biopreservation Market Worth 3,731.03 Million USD by 2020 4Biopreservation Market Worth 3,731.03 Million USD by 2020 5Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4
... At a meeting of the,Board of ... ), held today, a dividend of ... outstanding shares of Preferred Stock was,declared ... stockholders of record at the close,of ...
... Aida,Pharmaceuticals, Inc. (OTC Bulletin Board: AIDA) today announced ... ended September 30, 2007. Net,revenues totaled $7,373,770 for the ... period in 2006. Gross profit decreased by 2.66% due ... sales from Aida,s,transfusion and injection forms of etimicin sulfate ...
... Million Financing, WOBURN, Mass., Nov. 15 BioVex ... the treatment and,prevention of cancer and infectious disease, announced ... the completion of a,venture debt transaction, raising a total ... the capital to complete its preparations for, and,to commence, ...
Cached Biology Technology:Aida Files 10Q 2Aida Files 10Q 3Aida Files 10Q 4BioVex Closes Second Round of Series E Financing 2
Sheep polyclonal to hCG beta core fragment ( Abpromise for all tested applications). Antigen: Full length native protein (purified) from human urine. Entrez GeneID: 1082 Swiss Protein ID...
Evolutionarily conserved signaling intermediate in Toll pathway...
Anti-MMP-25 (Membrane-type MMP-6, Mt6MMP), hinge region; rabbit host...
Anti-MMP-25 (Membrane-type MMP-6, Mt6MMP), hinge region; rabbit host...
Biology Products: