Navigation Links
Dental pulp stem cells promote the survival and regeneration of retinal cells after injury
Date:7/7/2014

Researchers at the University of Birmingham, UK, led by Dr. Ben Scheven, Dr. Wendy Leadbeater and Ben Mead have discovered that stem cells isolated from the teeth, termed dental pulp stem cells (DPSC), can protect retinal ganglion cells (RGCs) from death following injury and promote regeneration of their axons along the optic nerve.

RGC loss is the leading cause of blindness and can arise through traumatic injury or degenerative diseases such as glaucoma. Neurotrophic factors (NTFs), which travel along the axon of a neuron to a cell body act as survival signals however, following injury or disease, this supply is lost and RGCs die. Supplementation of injured RGC with an alternative source of NTFs is paramount to protecting them from death.

The study, reported on Neural Regeneration Research (Vol. 9, No. 6, 2014), confirmed that DPSCs naturally express multiple NTFs which can supplement the lost supply of NTF and protect RGCs from death as well as promote regeneration of their axons. "Cell therapy is a promising treatment option as it provides a potentially limitless source of multiple growth factors for injured neurons", stressed first author Ben Mead. He also said "For clinical application, comparisons with other stem cells as well as development of safe delivery mechanisms are to be investigated in the future".


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert

Page: 1

Related biology news :

1. Transcendental experiences during meditation
2. GPS traffic maps for leatherback turtles show hotspots to prevent accidental fishing deaths
3. Penn Dental Medicine team identifies molecule critical to healing wounds
4. Flow restrictors may reduce young childrens accidental ingestion of liquid medications
5. CWRU dental researchers NIDCR grant targets oral bacteria and fetal death link
6. Surge in children accidentally eating marijuana-laced foods
7. Accidental discovery may lead to improved polymers
8. ACMG releases report on incidental findings in clinical exome and genome sequencing
9. Measuring mercury: Common test may overestimate exposure from dental amalgam fillings
10. 2 Cell Transplantation studies impact dental stem cell research for therapeutic purposes
11. Dental X-rays linked to common brain tumor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... 2017  On April 6-7, 2017, Sequencing.com will host ... hackathon at Microsoft,s headquarters in Redmond, ... on developing health and wellness apps that provide a ... Genome is the first hackathon for personal genomics ... companies in the genomics, tech and health industries are ...
(Date:3/29/2017)... March 29, 2017  higi, the health IT company ... North America , today announced a Series ... acquisition of EveryMove. The new investment and acquisition accelerates ... tools to transform population health activities through the collection ... higi collects and secures data today on ...
(Date:3/24/2017)... , March 24, 2017 The Controller General of ... Mr. Abdulla Algeen have received the prestigious international IAIR Award ... Continue Reading ... ... and Deputy Controller Abdulla Algeen (small picture on the right) have received ...
Breaking Biology News(10 mins):
(Date:8/10/2017)... (PRWEB) , ... August 09, 2017 , ... Okyanos Center ... take place at the Pelican Bay Hotel in Freeport, Grand Bahama on September 27, ... is required. , With oversight from the Ministry of Health’s National Stem Cell ...
(Date:8/10/2017)... ... August 10, 2017 , ... DrugDev and the ... to demonstrate how Good Clinical Practice (GCP) can be used throughout the site ... webinar will discuss the importance of GCP compliance, how sites are affected by GCP ...
(Date:8/10/2017)... ... August 10, 2017 , ... CNA ... outlet had initiated coverage on Next Group Holdings, Inc. and see's significant opportunity ... geared toward those that cannot engage in traditional banking services. According to industry ...
(Date:8/10/2017)... Wash., Aug. 10, 2017   BioLife Solutions , ... manufacturer and marketer of proprietary clinical grade cell and ... media ("BioLife" or the "Company"), today reported operational ... months ended June 30, 2017. Revenue from ... $2.6 million in the second quarter of 2017, an ...
Breaking Biology Technology: