Navigation Links
Dental pulp stem cells promote the survival and regeneration of retinal cells after injury
Date:7/7/2014

Researchers at the University of Birmingham, UK, led by Dr. Ben Scheven, Dr. Wendy Leadbeater and Ben Mead have discovered that stem cells isolated from the teeth, termed dental pulp stem cells (DPSC), can protect retinal ganglion cells (RGCs) from death following injury and promote regeneration of their axons along the optic nerve.

RGC loss is the leading cause of blindness and can arise through traumatic injury or degenerative diseases such as glaucoma. Neurotrophic factors (NTFs), which travel along the axon of a neuron to a cell body act as survival signals however, following injury or disease, this supply is lost and RGCs die. Supplementation of injured RGC with an alternative source of NTFs is paramount to protecting them from death.

The study, reported on Neural Regeneration Research (Vol. 9, No. 6, 2014), confirmed that DPSCs naturally express multiple NTFs which can supplement the lost supply of NTF and protect RGCs from death as well as promote regeneration of their axons. "Cell therapy is a promising treatment option as it provides a potentially limitless source of multiple growth factors for injured neurons", stressed first author Ben Mead. He also said "For clinical application, comparisons with other stem cells as well as development of safe delivery mechanisms are to be investigated in the future".


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert

Page: 1

Related biology news :

1. Transcendental experiences during meditation
2. GPS traffic maps for leatherback turtles show hotspots to prevent accidental fishing deaths
3. Penn Dental Medicine team identifies molecule critical to healing wounds
4. Flow restrictors may reduce young childrens accidental ingestion of liquid medications
5. CWRU dental researchers NIDCR grant targets oral bacteria and fetal death link
6. Surge in children accidentally eating marijuana-laced foods
7. Accidental discovery may lead to improved polymers
8. ACMG releases report on incidental findings in clinical exome and genome sequencing
9. Measuring mercury: Common test may overestimate exposure from dental amalgam fillings
10. 2 Cell Transplantation studies impact dental stem cell research for therapeutic purposes
11. Dental X-rays linked to common brain tumor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... May 23, 2017  Hunova, the first robotic gym for the rehabilitation ... officially launched in Genoa, Italy . The first 30 ... and the USA . The technology was developed and ... by the IIT spin-off Movendo Technology thanks to a 10 million euro ... Release, please click: ...
(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/18/2017)... 2017  Socionext Inc., a global expert in SoC-based imaging and ... the M820, which features the company,s hybrid codec technology. A demonstration ... Probe, Inc., will be showcased during the upcoming Medtec Japan at ... the Las Vegas Convention Center April 24-27. ... Click here for an ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... , ... October 11, 2017 , ... ComplianceOnline’s Medical Device ... on 7th and 8th June 2018 in San Francisco, CA. The Summit brings together ... as several distinguished CEOs, board directors and government officials from around the world to ...
(Date:10/11/2017)... 11, 2017  VMS BioMarketing, a leading provider of patient ... Clinical Nurse Educator (CNE) network, which will launch this week. ... among health care professionals to enhance the patient care experience ... and other health care professionals to help women who have ... ...
(Date:10/11/2017)... ... 2017 , ... Disappearing forests and increased emissions are the main causes of ... year. Especially those living in larger cities are affected by air pollution related diseases. ... most pollution-affected countries globally - decided to take action. , “I knew I had ...
(Date:10/11/2017)... ... October 11, 2017 , ... Singh Biotechnology today announced that ... SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B VHH13 ... cross the cell membrane and bind intracellular STAT3 and inhibit its function. Dysregulation ...
Breaking Biology Technology: