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Defending the genome
Date:12/22/2011

lusters and alter the architecture in a way that makes new piRNAs that can silence the resident elements."

"The bottom line on our study is when you introduce a single, new transposon it leads to a genetic crisis that activates all the transposons in the genome and compromises fertility in these hybrids," said Theurkauf. "Remarkably, what emerges at the other end is an organism with an altered genome architecture that functionally recharges the piRNA clusters so they more effectively silence transposons."


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Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Source:Eurekalert

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