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Decreasing insulin resistance prevents obesity-related cardiovascular damage
Date:2/11/2009

be stopped. "Even if the blood glucose is normal at that moment, that tells you it has been high, that it's swinging," he says. The sugar-coated hemoglobin also can start sticking to blood vessel walls, a problem deletion of PTP1B also seems to fix. Hemoglobin is a protein and a binding receptor for sugar-modified proteins receptor for advanced glycation end products, or RAGE is up-regulated in obesity and down-regulated in mice missing PTP1B.


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Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
Source:Eurekalert

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