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Decades on, bacterium's discovery feted as paragon of basic science
Date:9/12/2013

Award, an award aimed at celebrating "seemingly obscure studies that have led to major breakthroughs and resulted in significant societal impact."

Conferred by a gaggle of organizations the American Association for the Advancement of Science, the Association of American Universities, the Association of Public and Land-grant Universities, the Breakthrough Institute, the Progressive Policy Institute, the Science Coalition, the Task Force on American Innovation, and United for Medical Research the Golden Goose Award is given for federally-funded research that has led to "demonstrable, significant human and economic benefits."

The enzyme derived from the Thermus aquaticus bacterium powers polymerase chain reaction, or PCR. It is a technique used routinely to take trace amounts of DNA and amplify it for identification or study. The Taq polymerase is useful because it is stable at the high temperatures PCR requires to denature DNA and exponentially replicate target strands. The technology for which its inventor, Kary Mullis, was awarded the Nobel Prize is widely used in molecular biology, criminal forensics and medical diagnostics.

The Golden Goose Award was originally conceived by Congressman Jim Cooper of Tennessee to help educate members of Congress and the public about the value of basic scientific research. The name is a play on the Golden Fleece Awards, given by the late Wisconsin Sen. William Proxmire between 1975 and 1988, targeting specific federally funded research grants as examples of government waste.

"We've all read stories about the study with the wacky title, the research project from left field," Cooper says. "But off-the-wall science yields medical miracles. We can't abandon research funding only because we can't predict how the next miracle will happen."

Taq polymerase has gone on to be a workhorse molecule of science in good measure because Brock and Freeze deposited samples of the organism in t
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Contact: Tom Brock
tdbrock@charter.net
608-238-5050
University of Wisconsin-Madison
Source:Eurekalert

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