Dartmouth researchers identify an important gene for a healthy, nutrit...( Dartmouth researchers identify an im...)

Dartmouth researchers identify an important gene for a healthy, nutritious plant.

The research paper, published with colleagues from Colorado State University and the University of South Carolina, appeared in the early online edition of the Proceedings of the National Academy of Science during the week of July 21.

"There's a lot of attention today on global food shortages," says Mary Lou Guerinot, the principal investigator on the study and one of the authors of the paper. "We've found a gene that is key for proper chloroplast function. This finding might some day help scientists develop plants that grow better and can serve as more nutritious food."

During photosynthesis, chloroplasts are the subcellular compartment used by plant cells to convert light energy to sugars, fueling the plant. This process in the chloroplasts requires iron, and up to 90 percent of the iron in leaf cells is located in chloroplasts. In this study, Guerinot and her colleagues provide molecular evidence that FRO7, a gene in the FRO family, is involved in chloroplast iron acquisition and is required for efficient photosynthesis. The FRO family is a group of proteins that transfers electrons from ferric iron (Fe3+) to reduce it to another kind of iron (Fe2+). This same lab showed that this process (reduction of iron) was essential for plants to take up iron into the roots from the soil in a study published in 1999 in Nature.

"We have now shown that an analogous process is required for proper chloroplast function," says Guerinot. "Moreover, without FRO7, plants sown in iron deficient soil died as young seedlings. Our findings are of particular interest because how iron gets into chloroplasts has not been well understood despite the significance of iron in chloroplasts."

Guerinot explains that one-third of the soil worldwide is iron deficient, so it is important to understand how plants acquire iron, allocate iron to different parts of
'/>"/>